CARDIOVASCULAR JOURNAL OF AFRICA: VOLUME 15, ISSUE 2, MARCH 2004
  1. Title: The South African Lipid Guidelines : is there a need for an update? : editorial
    Authors: Raal, F.J.; Schamroth, C.; Klug, E.; Mills, P.
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.53-54
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  2. Title: New developments in pharmacotherapy : editorial
    Authors: Thompson, Gilbert R.
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.56-58
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  3. Title: Letter to the editor
    Authors: Bertrand, Edmond
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.58
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  4. Title: Facets of the metabolic syndrome in Dahl hypertensive rats : cardiovascular topics
    Authors: Channa, M.L.; Somova, L.; Nadar, A.
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.61-63
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    Abstract: We recently established that the Dahl salt-sensitive rat, a model for genetic salt-sensitive hypertension, was insulin resistant. This study was undertaken to evaluate whether other features of the metabolic syndrome developed in this animal model.
    Two groups of 16 Dahl salt-sensitive (DSS) rats and their controls, Dahl salt-resistant (DSR) rats were used. For eight weeks, half of each group was fed a standard diet with low sodium content (85 mmol Na/kg diet) while the remainder was fed a high-sodium diet (340 mmol Na/kg diet). Weekly systolic and diastolic blood pressures were measured for all animals. At the end of eight weeks, the urinary Na+/K+ ratio, fasting blood glucose, plasma uric acid and blood lipids were determined for all animals. The same parameters were measured in two additional matched weanling DSS and DSR groups of eight animals each.
    Adult DSS rats became hypertensive, with the DSS high-salt group exhibiting both genetic hypertension and the pressor effects of a high-salt diet. The DSS highsalt and weanling groups exhibited a lowered urinary Na+/K+ ratio, indicative of greater sodium retention, when compared to their respective DSR groups (p < 0.05). No strain differences were observed in the uric acid levels. However a high-salt diet in both DSS and DSR groups elevated uric acid levels. Weanling and DSS high-salt groups showed increased total plasma cholesterol when compared to their corresponding DSR groups (p < 0.05). In addition, the DSS high-salt group also had both increased total plasma cholesterol and high-density lipoprotein (HDL) cholesterol when compared to the DSS low-salt group (p < 0.05). No significant differences in blood glucose and plasma insulin were observed in the adult groups. The weanling DSS group showed a marked hyperinsulinaemia, suggesting that DSS rats were possibly insulin resistant even before hypertension was fully established. This could indicate that insulin resistance and hypertension may be inherited as separate traits that develop in a parallel but independent manner.
     
  5. Title: Supraventricular tachycardia in children : cardiovascular topics
    Authors: Van der Merwe, D.M.; Van der Merwe, P.L.
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.64-69
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    Abstract: The mechanisms causing different supraventricular tachycardias can be identified with the aid of the 12-lead ECG using Tipple's approach. The main aims of this retrospective study were to use the 12-lead ECG to determine the underlying mechanisms of supraventricular arrhythmias and to evaluate the effectiveness of the treatment modalities used.
    Forty-one patients were included in the study. The main findings were: nine of the 41 patients had atrial tachycardias while junctional tachycardia occurred in 32/41 of our patients. The underlying mechanisms causing the junctional tachycardias were: AVNRT (n = 21), AVRT (n = 10) and JET (n = 1). Of the 10 patients presenting with AVRT, eight were less than one year old. AVNRT occurred more often in the older age group (>1 year of age). Fifteen of the 41 patients had spontaneous cessation of their supraventricular tachycardia.
    The drug most commonly used during the acute and long-term phases was digoxin. Amiodarone was used in six patients with an 80% success rate. In the early 80s verapamil was used in five patients with a 100% success rate. It is important to note that verapamil is no longer used in children due to its side effects. Lately, adenosine phosphate is the drug of choice in most supraventricular tachycardias.
    The management of supraventricular tachycardias in paediatric practice is mainly based on clinical studies and individual experience. Care must therefore be taken to choose medication regimens that are likely to be effective with the minimum risk of potentiating abnormal haemodynamics or conduction.
     
  6. Title: High-dose atorvastatin therapy is required for significant improvement of endothelial function in heterozygous familial hypercholesterolaemic patients : cardiovascular topics
    Authors: Susan L. Brown,; Raal, Frederick J.; Panz, Vanessa R.; Stevens, Belinda A.; Veller, Martin G.
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.70-75
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    Abstract: This study evaluated endothelial dysfunction (ED) by measuring flow-mediated vasodilation (FMD) and for six months documented changes in ED, LDL-C levels and serum concentrations of inflammatory markers with high- and low-dose atorvastatin therapy. In 23 heterozygous familial hypercholesterolaemic (FH) patients, FMD, LDL-C and inflammatory markers (sVCAM-1, sICAM-1, E-selectin and highly sensitive C-reactive protein) were measured at baseline (untreated) and on atorvastatin 20 and 80 mg/day. In untreated patients, FMD was significantly reduced (mean + SD = 3.09 + 0.91%) compared with 10 normocholesterolaemic controls (8.71 + 2.41%; p < 0.01). FMD improved non-significantly with atorvastatin 20 mg/day (5.60 + 1.17%), but showed a significant improvement (8.54 + 1.11%; p < 0.01) with atorvastatin 80 mg/day. LDL-C decreased markedly (-42.4%; p < 0.0001) on 20 mg/day and decreased further (-48.6%; p < 0.05) on 80 mg/day. FMD improvement, however, did not correlate with LDL-C reduction. No significant changes occurred in any inflammatory markers. We concluded that ED was present in untreated FH patients and improved significantly on high-dose atorvastatin. There was no correlation between the changes in FMD and LDL-C, suggesting either a LDLC- independent effect on ED, or that a marked reduction in LDL-C is required to normalise ED in FH.
     
  7. Title: The William Nelson ECG Quiz
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.75, 80
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  8. Title: Effectiveness of single detachable COOK(R) coils in closure of the patent ductus arteriosus : cardiovascular topics
    Authors: Brown, Stephen; Bruwer, Andre; Al-Zaghal, Ahmed; Claassens, Antoinette
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.76-80
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    Abstract: Objective: To assess the efficacy and safety of single detachable coils in the closure of PDAs.
    Methods: Review of cases in which a single detachable coil was implanted. The diameter of the ampulla was used to select coil size. Diameters of the PDA, ampulla and residual shunts were measured.
    Results: There were 36 patients with a mean minimal ductal diameter of 2.2 + 0.6 mm. Immediately after implantation, 46% of the patients had residual shunts and after 24 hours, only 28%. A final spontaneous closure rate of 94% was observed after 21 months. There was a significant (p < 0.01) difference when minimal PDA diameter of those who had complete closure within 24 hours (median: 2 mm, interquartile range: 1.7-2.3 mm) was compared to those with a residual shunt (median: 2.5 mm, interquartile range: 2.3-3.2 mm). Negligible complications were experienced.
    Conclusion: Single Cook detachable coils are effective for PDA closure with a low complication rate if properly selected. There is a high rate of spontaneous closure of trivial residual shunts. In patients with a minimal ductal diameter > 2 mm and a residual shunt, more coils may be considered.
     
  9. Title: Transoesophageal atrial pacing stress echocardiography in coronary artery disease : role, principles and methodology : review article
    Authors: Goldberg, L.; Hagies, P.; Grigorov, V.
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.81-87
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    Abstract: This article reviews the physiology and methodology of transoesophageal atrial pacing stress echocardiography (TAPSE) and clarifies its place among the other stress modalities.
    TAPSE correlates well with myocardial perfusion stress scintigraphy and coronary angiography and is a simple and safe diagnostic option for patients with suspected or known CAD, including those with recent myocardial infarction. Furthermore, the results of TAPSE have prognostic significance in patients with uncomplicated MI.
    Although, it is a highly feasible and safe technique, the cardiologist should be directly involved in the procedure and the personnel must be well trained in a large number of tests, as for any other stress echocardiographic modalities.
     
  10. Title: Individualising heart failure patients to b-blocker therapy : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.88, 91
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  11. Title: Eprosartan dual action offers clinical benefit for elderly and overweight hypertensives : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.91-92
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  12. Title: Lipitor stops progression of plaque build-up in arteries : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.92
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  13. Title: Policosanol versus atorvastatin effective in cholesterol lowering and increased HDL-C levels : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.94
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  14. Title: CHARM shows improvement in NYHA functional class with candesartan : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.96-97
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  15. Title: Perindopril protects diabetics with coronary disease from cardiovascular death and heart attacks : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.98
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  16. Title: Cardio news
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.99-100
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The role of C-reactive protein:albumin ratio and neutrophil:lymphocyte ratio in predicting coronary artery disease

Published: 26 March 2024
 
Evaluation of cardiac function in paediatric Wilson’s disease patients with advanced echocardiographic modalities (strain and strain rate echocardiography)

Published: 26 March 2024
 
Comprehensive ABC (HbA1c, blood pressure, LDL-C) control and cardiovascular disease risk in patients with type 2 diabetes mellitus and major depressive disorder in a South African managed healthcare organisation

Published: 25 March 2024
 
The predictive value of triglyceride–glucose index for assessing the severity and MACE of premature coronary artery disease

Published: 21 February 2024
 
Obesity is associated with long-term outcome of catheter ablation of atrial fibrillation in patients with dilated cardiomyopathy

Published: 20 February 2024
 
Successful surgical treatment of left ventricular free wall rupture

Published: 19 February 2024
 
Correlation of osteopontin hormone with TIMI score and cardiac markers in patients with acute coronary syndrome presenting with chest pain

Published: 16 February 2024
 
Delayed diagnosis of cardiac amyloidosis in a West African octogenarian

Published: 12 February 2024
 
Impact of COVID-19 on cardiac surgery outcomes

Published: 12 February 2024
 
Percutaneous coronary intervention facilities in Nigeria

Published: 12 February 2024
 
Association of ratios of monocyte/high-density lipoprotein cholesterol and neutrophil/high-density lipoprotein cholesterol with atherosclerotic plaque type on coronary computed tomography

Published: 26 January 2024
 
Assessment of Tp–Te interval in patients with cardiac AL amyloidosis

Published: 15 January 2024
 
Association between Pfizer-BioNTech mRNA vaccine and myocardial infarction: clinical and angiographic insights

Published: 13 December 2023
 
Investigation of the effects of ellagic, vanillic and rosmarinic acid on reperfusion-induced renal injury

Published: 29 November 2023
 
A novel method that can be used in both the diagnosis and treatment of peripheral arterial disease in diabetics: vibration-mediated dilation

Published: 29 November 2023
 
Predictive values of stress hyperglycaemia and glycosylated haemoglobin on admission for long-term recovery of cardiac function in patients with acute myocardial infarction after primary percutaneous coronary intervention

Published: 22 November 2023
 
The relationship between epicardial adipose tissue and choroidal vascularity index in patients with hypertension

Published: 20 November 2023
 
Improving cardiac function of angiotensin receptor/neprilysin inhibitor in patients with acute myocardial infarction: a systematic review and meta-analysis

Published: 17 November 2023
 
Ultrasonographic assessment and clinical outcomes after deployment of a suture-mediated femoral vascular closure device

Published: 16 November 2023
 
Correlation between carotid intima–media thickness and patient outcomes in coronary artery disease in central South Africa

Published: 16 November 2023
 
Contemporary risk factors associated with ischaemic heart disease in central South Africa: a single-centre study

Published: 06 November 2023
 
Comparison of early postoperative results in patients with and without diabetes with low ejection fraction and normal serum creatinine values who underwent coronary artery bypass operation

Published: 27 October 2023
 
Coronary artery bypass grafting in a patient with situs inversus totalis

Published: 20 October 2023
 
Correlation between maternally expressed gene 3 expression and heart rate variability in heart failure patients with ventricular arrhythmia

Published: 06 October 2023
 
A novel U-shaped relationship between serum klotho and abdominal aortic calcification in the general population

Published: 05 October 2023
 
Echocardiographic multiparameter assessment for patients with heart failure with preserved ejection fraction and atrial fibrillation

Published: 04 October 2023
 
Relationship between adiponectin and copeptin levels with long-term cardiovascular mortality in ST-segment elevation myocardial infarction after percutaneous coronary intervention

Published: 04 October 2023
 
Six months of resistance training improves heart rate variability in the elderly

Published: 27 September 2023
 
Association between serum α-klotho level and the prevalence of heart failure in the general population

Published: 27 September 2023
 
The assessment of thoracal approaches in the treatment of aortic coarctation

Published: 15 September 2023
 
Point-of-care testing compared to gold-standard laboratory methods in the measurement of serum lipids

Published: 31 August 2023
 
Outcomes of single-ventricle physiology in central South Africa

Published: 25 August 2023
 
Comparison of serum lipoprotein(a) levels in young and middle-aged patients presenting for the first time with ST-elevation myocardial infarction: a single-centre study

Published: 25 August 2023
 
The value of measured partial oxygen pressure during pulmonary vein closure and the relationship with the diameter of the closed vein in patients with cryoablation

Published: 17 August 2023
 
Paying more attention to arterial hypertension, dyslipidaemia, women and the rural environment in our ongoing fight against cardiovascular diseases and their risk factors

Published: 17 August 2023
 
The relationship between serum osteoprotegerin levels and right atrial and ventricular speckle-tracking measurements in essential hypertension patients with normal left ventricular systolic function

Published: 27 July 2023
 
The association between CHA2DS2-VASc score and aortic valve sclerosis

Published: 26 July 2023
 
Oxidative metabolism of neutrophils in acute coronary syndrome

Published: 25 July 2023
 
Yield of family screening in dilated cardiomyopathy within low-income setting: Tanzanian experience

Published: 25 July 2023
 
Study of the mechanism of Shexiang Baoxin pill-mediated angiogenesis in acute myocardial infarction

Published: 04 July 2023
 
Effects of intravenous sodium thiosulfate on vascular calcification in dialysis patients with end-stage renal disease: a systematic review and meta-analysis

Published: 03 July 2023
 
Right ventricular function in treatment-naïve human immunodeficiency virus-infected patients

Published: 03 July 2023
 
Changes in blood pressure after catheter-based renal denervation in South Africa

Published: 28 June 2023
 
Effect of insulin resistance on left ventricular remodelling in essential hypertensives: a cross-sectional study

Published: 21 June 2023
 
Impact of the COVID-19 pandemic on cardiology fellowship training in a sub-Saharan African training centre: an African perspective

Published: 19 June 2023
 
The effects on clinical outcomes of administering medications together or separately in prolonged dual antiplatelet therapy after peripheral revascularisation

Published: 19 June 2023
 
Empagliflozin significantly prevents QTc prolongation due to amitriptyline intoxication

Published: 07 June 2023
 
Is the transradial approach associated with decreased acute kidney injury following percutaneous coronary intervention in patients not complicated by major bleeding and haemodynamic disturbance?

Published: 05 June 2023
 
Effect of lactate levels on extubation time in coronary artery bypass grafting surgery

Published: 05 June 2023
 
Evaluation of clinical results of esmarch bandage application in giant saphenous vein closure during endovenous glue ablation

Published: 03 June 2023
 
Right atrial strain in a normal adult African population according to age

Published: 02 June 2023
 
Long-term experience of the modified David V re-implantation technique for valve-sparing aortic root replacement

Published: 01 June 2023
 
Pre-eclampsia: does cardiac function differ in HIV-positive and -negative women?

Published: 11 May 2023
 
Systemic immune–inflammation index, and neutrophilto-lymphocyte and platelet-to-lymphocyte ratios can predict clinical outcomes in patients with acute coronary syndrome

Published: 05 May 2023
 
A strategy to improve adherence to guidelinedirected medical therapy (GDMT) and the role of the multidisciplinary team in a heart-failure programme

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Association between apelin-12 and creatine kinase-MB, depending on success of reperfusion in STEMI patients

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Investigation of left ventricular changes according to valve type in patients with surgical replacement due to isolated aortic stenosis

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Assessment value of the modified early warning score for long-term prognosis of older patients with chronic heart failure

Published: 28 April 2023
 
A cross-sectional study of the spectrum, aetiology and clinical characteristics of adult mitral valve disease at Chris Hani Baragwanath Academic Hospital

Published: 26 April 2023
 
Identification and treatment of asymptomatic central venous catheter thrombosis after TAVI

Published: 24 April 2023
 
Surgical experience in adults with Ebstein’s anomaly: long-term results

Published: 24 March 2023
 
Effect of different priming fluids on extravascular lung water, cell integrity and oxidative stress in cardiopulmonary bypass surgery

Published: 06 March 2023
 
Calcified right ventricular fibroma in an adult

Published: 03 March 2023
 
Arterial stiffness assessment in obese black South African patients

Published: 13 February 2023
 
Clinical characteristics, diagnostic methods and results of surgically treated histologically benign cardiac myxomas

Published:07 February 2023
 
Characteristics and immediate outcomes of patients who underwent percutaneous balloon mitral valvuloplasty at the Jakaya Kikwete Cardiac Institute, Tanzania

Published:06 February 2023
 
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