CARDIOVASCULAR JOURNAL OF AFRICA: VOLUME 15, ISSUE 2, MARCH 2004
  1. Title: The South African Lipid Guidelines : is there a need for an update? : editorial
    Authors: Raal, F.J.; Schamroth, C.; Klug, E.; Mills, P.
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.53-54
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
     
  2. Title: New developments in pharmacotherapy : editorial
    Authors: Thompson, Gilbert R.
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.56-58
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
     
  3. Title: Letter to the editor
    Authors: Bertrand, Edmond
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.58
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
     
  4. Title: Facets of the metabolic syndrome in Dahl hypertensive rats : cardiovascular topics
    Authors: Channa, M.L.; Somova, L.; Nadar, A.
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.61-63
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
    Abstract: We recently established that the Dahl salt-sensitive rat, a model for genetic salt-sensitive hypertension, was insulin resistant. This study was undertaken to evaluate whether other features of the metabolic syndrome developed in this animal model.
    Two groups of 16 Dahl salt-sensitive (DSS) rats and their controls, Dahl salt-resistant (DSR) rats were used. For eight weeks, half of each group was fed a standard diet with low sodium content (85 mmol Na/kg diet) while the remainder was fed a high-sodium diet (340 mmol Na/kg diet). Weekly systolic and diastolic blood pressures were measured for all animals. At the end of eight weeks, the urinary Na+/K+ ratio, fasting blood glucose, plasma uric acid and blood lipids were determined for all animals. The same parameters were measured in two additional matched weanling DSS and DSR groups of eight animals each.
    Adult DSS rats became hypertensive, with the DSS high-salt group exhibiting both genetic hypertension and the pressor effects of a high-salt diet. The DSS highsalt and weanling groups exhibited a lowered urinary Na+/K+ ratio, indicative of greater sodium retention, when compared to their respective DSR groups (p < 0.05). No strain differences were observed in the uric acid levels. However a high-salt diet in both DSS and DSR groups elevated uric acid levels. Weanling and DSS high-salt groups showed increased total plasma cholesterol when compared to their corresponding DSR groups (p < 0.05). In addition, the DSS high-salt group also had both increased total plasma cholesterol and high-density lipoprotein (HDL) cholesterol when compared to the DSS low-salt group (p < 0.05). No significant differences in blood glucose and plasma insulin were observed in the adult groups. The weanling DSS group showed a marked hyperinsulinaemia, suggesting that DSS rats were possibly insulin resistant even before hypertension was fully established. This could indicate that insulin resistance and hypertension may be inherited as separate traits that develop in a parallel but independent manner.
     
  5. Title: Supraventricular tachycardia in children : cardiovascular topics
    Authors: Van der Merwe, D.M.; Van der Merwe, P.L.
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.64-69
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
    Abstract: The mechanisms causing different supraventricular tachycardias can be identified with the aid of the 12-lead ECG using Tipple's approach. The main aims of this retrospective study were to use the 12-lead ECG to determine the underlying mechanisms of supraventricular arrhythmias and to evaluate the effectiveness of the treatment modalities used.
    Forty-one patients were included in the study. The main findings were: nine of the 41 patients had atrial tachycardias while junctional tachycardia occurred in 32/41 of our patients. The underlying mechanisms causing the junctional tachycardias were: AVNRT (n = 21), AVRT (n = 10) and JET (n = 1). Of the 10 patients presenting with AVRT, eight were less than one year old. AVNRT occurred more often in the older age group (>1 year of age). Fifteen of the 41 patients had spontaneous cessation of their supraventricular tachycardia.
    The drug most commonly used during the acute and long-term phases was digoxin. Amiodarone was used in six patients with an 80% success rate. In the early 80s verapamil was used in five patients with a 100% success rate. It is important to note that verapamil is no longer used in children due to its side effects. Lately, adenosine phosphate is the drug of choice in most supraventricular tachycardias.
    The management of supraventricular tachycardias in paediatric practice is mainly based on clinical studies and individual experience. Care must therefore be taken to choose medication regimens that are likely to be effective with the minimum risk of potentiating abnormal haemodynamics or conduction.
     
  6. Title: High-dose atorvastatin therapy is required for significant improvement of endothelial function in heterozygous familial hypercholesterolaemic patients : cardiovascular topics
    Authors: Susan L. Brown,; Raal, Frederick J.; Panz, Vanessa R.; Stevens, Belinda A.; Veller, Martin G.
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.70-75
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
    Abstract: This study evaluated endothelial dysfunction (ED) by measuring flow-mediated vasodilation (FMD) and for six months documented changes in ED, LDL-C levels and serum concentrations of inflammatory markers with high- and low-dose atorvastatin therapy. In 23 heterozygous familial hypercholesterolaemic (FH) patients, FMD, LDL-C and inflammatory markers (sVCAM-1, sICAM-1, E-selectin and highly sensitive C-reactive protein) were measured at baseline (untreated) and on atorvastatin 20 and 80 mg/day. In untreated patients, FMD was significantly reduced (mean + SD = 3.09 + 0.91%) compared with 10 normocholesterolaemic controls (8.71 + 2.41%; p < 0.01). FMD improved non-significantly with atorvastatin 20 mg/day (5.60 + 1.17%), but showed a significant improvement (8.54 + 1.11%; p < 0.01) with atorvastatin 80 mg/day. LDL-C decreased markedly (-42.4%; p < 0.0001) on 20 mg/day and decreased further (-48.6%; p < 0.05) on 80 mg/day. FMD improvement, however, did not correlate with LDL-C reduction. No significant changes occurred in any inflammatory markers. We concluded that ED was present in untreated FH patients and improved significantly on high-dose atorvastatin. There was no correlation between the changes in FMD and LDL-C, suggesting either a LDLC- independent effect on ED, or that a marked reduction in LDL-C is required to normalise ED in FH.
     
  7. Title: The William Nelson ECG Quiz
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.75, 80
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
     
  8. Title: Effectiveness of single detachable COOK(R) coils in closure of the patent ductus arteriosus : cardiovascular topics
    Authors: Brown, Stephen; Bruwer, Andre; Al-Zaghal, Ahmed; Claassens, Antoinette
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.76-80
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
    Abstract: Objective: To assess the efficacy and safety of single detachable coils in the closure of PDAs.
    Methods: Review of cases in which a single detachable coil was implanted. The diameter of the ampulla was used to select coil size. Diameters of the PDA, ampulla and residual shunts were measured.
    Results: There were 36 patients with a mean minimal ductal diameter of 2.2 + 0.6 mm. Immediately after implantation, 46% of the patients had residual shunts and after 24 hours, only 28%. A final spontaneous closure rate of 94% was observed after 21 months. There was a significant (p < 0.01) difference when minimal PDA diameter of those who had complete closure within 24 hours (median: 2 mm, interquartile range: 1.7-2.3 mm) was compared to those with a residual shunt (median: 2.5 mm, interquartile range: 2.3-3.2 mm). Negligible complications were experienced.
    Conclusion: Single Cook detachable coils are effective for PDA closure with a low complication rate if properly selected. There is a high rate of spontaneous closure of trivial residual shunts. In patients with a minimal ductal diameter > 2 mm and a residual shunt, more coils may be considered.
     
  9. Title: Transoesophageal atrial pacing stress echocardiography in coronary artery disease : role, principles and methodology : review article
    Authors: Goldberg, L.; Hagies, P.; Grigorov, V.
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.81-87
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
    Abstract: This article reviews the physiology and methodology of transoesophageal atrial pacing stress echocardiography (TAPSE) and clarifies its place among the other stress modalities.
    TAPSE correlates well with myocardial perfusion stress scintigraphy and coronary angiography and is a simple and safe diagnostic option for patients with suspected or known CAD, including those with recent myocardial infarction. Furthermore, the results of TAPSE have prognostic significance in patients with uncomplicated MI.
    Although, it is a highly feasible and safe technique, the cardiologist should be directly involved in the procedure and the personnel must be well trained in a large number of tests, as for any other stress echocardiographic modalities.
     
  10. Title: Individualising heart failure patients to b-blocker therapy : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.88, 91
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
     
  11. Title: Eprosartan dual action offers clinical benefit for elderly and overweight hypertensives : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.91-92
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
     
  12. Title: Lipitor stops progression of plaque build-up in arteries : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.92
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
     
  13. Title: Policosanol versus atorvastatin effective in cholesterol lowering and increased HDL-C levels : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.94
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
     
  14. Title: CHARM shows improvement in NYHA functional class with candesartan : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.96-97
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
     
  15. Title: Perindopril protects diabetics with coronary disease from cardiovascular death and heart attacks : drug trends in cardiology
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.98
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
     
  16. Title: Cardio news
    From: Cardiovascular Journal of South Africa, Vol 15, Issue 2, Mar / Apr
    Published: 2004
    Pages: p.99-100
    Full text: Click here to order
    Full text: Click here to read online (Login Required)
Prevalence and predictive value of electrocardiographic abnormalities in pulmonary hypertension: evidence from the Pan-African Pulmonary Hypertension Cohort (PAPUCO) study

Published: 11 October 2017
 
 
Unusually aggressive immature neo-intimal hyperplasia causing in-stent restenosis

Published: 10 October 2017
 
 
Cardiac diastolic function after recovery from pre-eclampsia

Published: 31 August 2017
 
 
The effect of iloprost and sildenafil, alone and in combination, on myocardial ischaemia and nitric oxide and irisin levels

Published: 31 August 2017
 
 
The aetiology of cardiovascular disease: a role for mitochondrial DNA?

Published: 25 August 2017
 
 
The effect of lifestyle interventions on maternal body composition during pregnancy in developing countries: a systematic review

Published: 24 August 2017
 
 
Red cell distribution width is correlated with extensive coronary artery disease in patients with diabetes mellitus

Published: 23 August 2017
 
 
A survey of non-communicable diseases and their risk factors among university employees: a single institutional study

Published: 15 August 2017
 
 
A comparative study on the cardiac morphology and vertical jump height of adolescent black South African male and female amateur competitive footballers

Published: 15 August 2017
 
 
Efficacy of cardiac magnetic resonance imaging in a sub-aortic aneurysm case

Published: 29 June 2017
 
 
A preliminary review of warfarin toxicity in a tertiary hospital in Cape Town, South Africa

Published: 21 June 2017
 
 
Effects of age on systemic inflamatory response syndrome and results of coronary bypass surgery

Published: 23 May 2017
 
 
Clinical profile, management and outcomes of patients with pulmonary embolism: a retrospective tertiary centre study in Angola

Published: 17 May 2017
 
 
Role of melatonin in glucose uptake by cardiomyocytes from insulin-resistant Wistar rats

Published: 17 May 2017
 
 
Atorvastatin inhibits cholesterol-induced caspase-3 cleavage through down-regulation of p38 and up-regulation of Bcl-2 in the rat carotid artery

Published: 10 May 2017
 
 
Relationship between coronary tortuosity and plateletcrit coronary tortuosity and plateletcrit

Published: 26 April 2017
 
 
Electrocardiographic abnormalities in treatment-naïve HIV subjects in south-east Nigeria

Published: 24 March 2017
 
 
Medication adherence among cardiac patients in Khartoum State, Sudan: a cross-sectional study

Published: 24 March 2017
 
 
Prevalence of rheumatic valvular heart disease in Rwandan school children: echocardiographic evaluation using the World Heart Federation criteria

Published: 1 March 2017
 
 
Factors affecting interest in cardiothoracic surgery among junior surgical residents in Nigeria

Published: 1 March 2017
 
 
New World’s old disease: cardiac hydatid disease and surgical principles

Published: 20 February 2017
 
 
Right ventricular strain as predictor of pulmonary complications in patients with femur fracture

Published: 01 February 2017
 
 
Atrial myxoma: a rare cause of hemiplegia in children

Published: 09 December 2016
 
 
Click here for more information on our Online First Publication Service »
ABOUT CVJA

Editorial Board
CVJA Info
Conference Calendar
Contact Us
JOURNAL ARTICLES

Current Issue
Online First Articles
Article Search
Journal Archive
Older Journal Archive
For the Patient
SERVICES

Log onto Sabinet
Submit Manuscript
Article Search
Subscribe to Journal (RSA)
Subscribe to Journal (Other)
Register for Editors’ Choice
Copyright Clearance
Why Should I Publish?
Register for Content Alerts
INFORMATION

Instructions for Authors
Submit Manuscript
Advertising Rates Card
Reviewers Information
MEDIA RESOURCES

Read Journal Online
Article Search
Chronic Heart Failure Guide
Video Archive
Follow us on Twitter
All Rights Reserved 2017 © Clinics Cardive Publishing (Pty) Ltd.
The content on this website is intended for healthcare professionals unless stated otherwise.

Advertisements on this website do not constitute a guarantee or endorsement by the journal or publisher of the quality or value
of such products or of the claims made for it by its manufacturer.

Website Development by Design Connection.