| FROM THE EDITOR'S DESK | 7 |
| CARDIOVASCULAR TOPICS | 8 |
| The design and development of a stented tissue mitral and aortic heart valve replacement for human implantation | 8 |
| Prognostic role of Helicobacter pylori infection in acute coronary syndrome: a prospective cohort study | 13 |
| The clinical, electrocardiographic and echocardiographic characteristics and long-term outcome of patients with tachycardia-induced cardiomyopathy | 18 |
| The value of serum tumour markers in the prediction of aetiology and follow up of patients with pericardial effusion | 25 |
| Prevalence of residual left ventricular structural changes after one year of antihypertensive treatment in patients of African descent: role of 24-hour pulse pressure | 29 |
| The role of angiogenic, anti-angiogenic and vasoactive factors in pre-eclamptic African women: early- versus late-onset pre-eclampsia | 35 |
| REVIEW ARTICLE | 42 |
| YOUR LIFE AND YOUR HEART | 52 |
| DRUG TRENDS | 50 |
| CASE REPORTS | 63 |
| Iatrogenic hydropneumopericardium | 63 |
| Spontaneous coronary artery dissection associated with Leriche syndrome | 65 |
| Multiple gene polymorphisms predisposing to the prothrombotic state in an adolescent with acute myocardial infarction | 68 |
| Very late thrombosis of a paclitaxel-eluting stent after 72 months in a patient on dual anti-platelet therapy | 71 |
| Post-infarction myocardial rupture: a case of pericardial tamponade salvaged by auto-blood transfusion | 74 |
| Heart failure and cardiogenic shock associated with the | 76 |