17767
S5 LYRICA
®
25 mg, 75 mg and 150 mg capsules. (Reg. No’s: A39/2.5/0264, 0266, 0268). Each hard capsule contains 25 mg, 75 mg, or 150 mg of pregabalin respectively.
LICENCE HOLDER:
Pfizer
Laboratories (Pty) Ltd. Reg. No. 1954/000781/07. P O Box 783720, Sandton, 2146. Tel. No.: 0860 PFIZER (734937). Please refer to detailed package insert for full prescribing information (PI Ref 02/02/10).
06/LYR/08/11/JA.
LYRICA
®
- early and sustained
relief in the
treatment of
Neuropathic Pain
*5,6,7
Early onset - reduction of
pain within first week
5,6
Sustained pain relief
7
Simple BD dosing
*
South African Registration:
- Diabetic Peripheral Neuropathy
- Postherpetic neuralgia
International Guidelines:
1. US: Postherpetic neuralgia
2. Canada: Chronic Neuropathic Pain
3,4. EU: Neuropathic Pain
References: 1.
Dubinksy RM, Kabbani H, El-Chami Z, Boutwell C, Ali H. Practice Parameter: Treatment of postherpetic neuralgia – An evidence-based report of the Quality Standards Subcommittee of
the American Academy of Neurology.
Neurology
2004;
63
:959-965.
2.
Moulin DE, Clark AJ, Gilron I, Ware MA, Watson CPN, Sessle BJ,
et al.
Pharmacological management of chronic neuropathic pain
- Consensus statement and guidelines from the Canadian Pain Society.
Pain Res Manage
2007;
12
(1):13-21.
3.
Attal N, Cruccu G, Haanpää M, Hansson P, Jensen TS, Nurmikko T,
et al.
EFNS guidelines
on pharmacological treatment of neuropathic pain.
Eur J Neurol
2006;
13
:1153-1169.
4.
Dworkin RH, O’Connor AB, Backonja M, Farrar JT, Finnerup NB, Jensen TS,
et al.
Pharmacologic management of
neuropathic pain: Evidence-based recommendations.
Pain
2007;
132
:237-251.
5.
Freeman R, Durso-DeCruz E, Emir B. Efficacy, safety, and tolerability of pregabalin treatment for painful diabetic peripheral
neuropathy: findings from seven randomised, controlled trials across a range of doses.
Diabetes Care
2008;
31
(7):1448-1454.
6.
Sabatowski R, Gálvez R, Cherry DA, Jacquot F, Vincent E, Maisonobe P,
et
al.
The 1008-045 Study Group. Pregabalin reduces pain and improves sleep and mood disturbances in patients with post-herpetic neuralgia: results of a randomized, placebo-controlled trial:
Pain
2004;
109
:26-35.
7.
Stacey BR, Dworkin RH, Murphy K, Sharma U, Emir B, Griesing T. Pregabalin in the Treatment of Refractory Neuropathic Pain: Results of a 15-Month Open-Label Trial.
Pain Med
Mar 11,
2008. [Epub ahead of print].
