Editors
Acting Editor in Chief
(South Africa)
Prof PA Brink
Assistant Editor
Prof JAMES KER (JUN)
Regional Editor
DR A Dzudie
Regional Editor (Kenya)
Dr F Bukachi
Regional Editor (South Africa)
PROF R DELPORT
Editorial Board
prof PA Brink
Experimental & Laboratory
Cardiology
PROF R DELPORT
Chemical Pathology
PROF MR ESSOP
Haemodynamics, Heart Failure
& Valvular Heart Disease
DR OB FAMILONI
Clinical Cardiology
DR V GRIGOROV
Invasive Cardiology & Heart
Failure
PROF J KER (SEN)
Hypertension, Cardiomyopathy,
Cardiovascular Physiology
DR J LAWRENSON
Paediatric Heart Disease
PROF A LOCHNER
Biochemistry/Laboratory
Science
PROF BM MAYOSI
Chronic Rheumatic Heart
Disease
DR MT MPE
Cardiomyopathy
PROF DP NAIDOO
Echocardiography
PROF B RAYNER
Hypertension/Society
PROF MM SATHEKGE
Nuclear Medicine/Society
PROF YK SEEDAT
Diabetes & Hypertension
PROF H DU T THERON
Invasive Cardiology
International
Advisory Board
PROF DAVID CELEMAJER
Australia (Clinical Cardiology)
PROF KEITH COPELIN FERDINAND
USA (General Cardiology)
DR SAMUEL KINGUE
Cameroon (General Cardiology)
DR GEORGE A MENSAH
USA (General Cardiology)
PROF WILLIAM NELSON
USA (Electrocardiology)
DR ULRICH VON OPPEL
Wales (Cardiovascular Surgery)
PROF PETER SCHWARTZ
Italy (Dysrhythmias)
PROF ERNST VON SCHWARZ
USA (Interventional Cardiology)
ISSN 1995-1892 (print)
ISSN 1680-0745 (online)
Cardiovascular Journal of Africa
CONTENTS
INDEXED AT SCISEARCH (SCI), PUBMED, PUBMED CENTRAL AND SABINET
Vol 25, No 1, JANUARY/FEBRUARY 2014
SUBJECT Editors
Nuclear Medicine and Imaging
DR MM SATHEKGE
Heart Failure
Dr g visagie
Paediatric
dr s brown
Renal Hypertension
dr brian rayner
Surgical
dr f aziz
Adult Surgery
dr j rossouw
Epidemiology and
Preventionist
dr ap kengne
Editorial
3 From the economics of TAVI and the pathophysiology of heart and vessel disease to
metabolic disease in Africa and the developing world
PA Brink
Cardiovascular Topics
4 Vascular calcification is not associated with increased ambulatory central aortic
systolic pressure in prevalent dialysis patients
RJ Freercks • CR Swanepoel • KL Turest-Swartz • HRO Carrara • SEI Moosa • AS Lachman •
BL Rayner
9 Endothelial function and germ-line ACE I/D, eNOS and PAI-1 gene profiles in patients
with coronary slow flow in the Canakkale population: multiple thrombophilic gene
profiles in coronary slow flow
E Gazi • A Temız • B Altun • A Barutcu • F Silan • Y Colkesen • O Ozdemir
15 Atrial electromechanical coupling intervals in pregnant subjects
B Altun • H Tasolar • E Gazi • AC Gungor • A Uysal • A Temiz • A Barutcu • G Acar •
Y Colkesen • U Ozturk • M Akkoyun
21 An analysis of real-world cost-effectiveness of TAVI in South Africa
TA Mabin • P Candolfi
27 Prevalence of the metabolic syndrome and determination of optimal cut-off values of
waist circumference in university employees from Angola
P Magalhães • DP Capingana • JG Mill
34 Echocardiographic estimation of left ventricular filling pressures in patients with mitral
valve stenosis
R Sattarzadeh • A Tavoosi • P Tajik