{"id":4389,"date":"2025-04-29T12:18:18","date_gmt":"2025-04-29T10:18:18","guid":{"rendered":"https:\/\/cvja.co.za\/journal\/?p=4389"},"modified":"2025-06-09T18:28:28","modified_gmt":"2025-06-09T16:28:28","slug":"cvja-2023-060","status":"publish","type":"post","link":"https:\/\/cvja.co.za\/journal\/cvja-2023-060\/","title":{"rendered":"The predictive value of triglyceride\u2013glucose index for assessing the severity and MACE of premature coronary artery disease"},"content":{"rendered":"    <div id=\"article\">                                                                                                                        \r\n        <div id=\"title-container\">                                                                                                    \r\n        <div id=\"authors-title\">                                                                                                            \r\n        <!--Aurthors under Title-->                                                                                                            \r\n            Ling Yang, Yu Peng, Zheng Zhang\r\n                                                                                                            \r\n        <\/div>        \r\n<\/div>                                                                                                                            \r\n            <div id=\"copyright\">\r\n        <strong>Copyright:<\/strong> Clinics Cardive Publishing (Pty) Ltd. publisher\r\n        of Cardiovascular Journal of Africa.<\/div>\r\n    <div style=\"clear: both;\"><\/div>                                                                                                                                \r\n        <div id=\"article-abstract\">                                                                                                            \r\n            <div id=\"abstract-title\">                                                                                                        \r\n                    Abstract                                                                                                                \r\n                <\/div>                                                                                                                        \r\n                                                                                                                                \r\n            <div id=\"abstract-content\">                                                                                                        \r\n            <!--Content of Abstract Article-->                                                                                                \r\n            <!--<strong>\"Abstract titles\":<\/strong>-->                                                                                        \r\n            <!--<br\/> at the end of each section!!-->                                                                                        \r\n                                                                                                                                            \r\n        <strong>Objective:<\/strong>                                                                                                    \r\n                                                                                                                                                    \r\n        The aim of this study was to investigate the predictive value of the triglyceride\u2013glucose (TyG) index to assess the severity and major adverse cardiovascular events (MACE) of patients in hospital with premature coronary artery disease (PCAD).                                                                                                                    \r\n                <br \/>                                                                                                                            \r\n                                                                                                                                                \r\n        <strong>Methods:<\/strong>                                                                                                    \r\n                                                                                                                                                    \r\n        A total of 300 patients with PCAD, diagnosed by coronary angiography (CAG), were enrolled in this study. According to the tertiles of TyG index, the 300 patients were divided into a T1 (n = 100), T2 (n = 100) and T3 group (n = 100). According to the presence or absence of MACE, the 300 patients were divided into a MACE (n = 80) and a non-MACE group (n = 220). The patients\u2019 clinical data were compared between the groups, the relationship between TyG index and the severity of PCAD and MACE were analysed through multivariable logistic regression analysis, and their predictive value was detected using receiver operating characteristic (ROC) curves.                                                                                                                    \r\n                <br \/>                                                                                                                            \r\n                                                                                                                                                \r\n        <strong>Results:<\/strong>                                                                                                    \r\n                                                                                                                                                    \r\n        Multivariable logistic regression analysis showed that the TyG index was an independent risk factor for the severity of PCAD and MACE. The area under the ROC curve was 0.833 and 0.807, respectively (all p &lt; 0.05).\r\n                                                                                                                    \r\n                <br \/>                                                                                                                            \r\n                                                                                                                                                \r\n        <strong>Conclusion:<\/strong>                                                                                                    \r\n                                                                                                                                                    \r\n         The TyG index was independently associated with the severity of PCAD and MACE, and had a good predictive value.                                                                                                                    \r\n                <br \/>                                                                                                                            \r\n                                                                                                                                                \r\n            <\/div>                                                                                                                            \r\n        <\/div>                                                                                                                                    \r\n                                                                                                                                        \r\n                                                                                                                                                \r\n        <div id=\"keywords\">                                                                                                                    \r\n                                                                                                                                            \r\n            <strong>Keywords:<\/strong>                                                                                                        \r\n                                                                                                                                            \r\n            <strong>premature coronary artery disease, triglyceride\u2013glucose index, severity, major adverse cardiovascular events<\/strong>                                                                                                                                                                                                                    \r\n                                                                                                                                                \r\n        <\/div>                                                                                                                                    \r\n                                                                                                                                                \r\n    <div id=\"publish-info\">                                                                                                                    \r\n                                                                                                                                \r\n    <strong>Submitted:<\/strong> September 10, 2023;<!--Month day, year; -->    \r\n    <strong>Accepted:<\/strong> November 8, 2023;<!--Month day, year; -->        \r\n    <strong>Published Online First:<\/strong> February 21, 2024;<!--Month day, year; -->                                                                        \r\n    <strong>Published:<\/strong> December 15, 2024<!--Month day, year; -->                                                                                                                            <br \/>                                                            \r\n        <em>Cardiovasc J Afr 2024; <b>35<\/b>: 356-361<!--pg no. till pg no. \"eg. 4-7\"--><\/em>\r\n        <br \/><strong>Volume 35, Issue 4<\/strong> <br \/>    \r\n                                                                        \r\n        <\/div>                                                                                                                            \r\n                                                                                                                                        \r\n    <div id=\"DOI\">                                                                                                                    \r\n            DOI Citation Reference: dx.doi.org\/10.5830\/CVJA-2023-060<!--DOI number-->                                                                \r\n        <\/div>                                                                                                                            \r\n                    \r\n            <div id=\"author-affiliation\">                                                                                                \r\n                                                                                                                                        \r\n                <strong>The First Clinical Medicine School of Lanzhou University, Lanzhou, China<\/strong>    <br \/>                                                                                \r\n                                                                                                                                        \r\n                \r\nLing Yang, MMed<br \/>    \r\n                                                                                                                                        \r\n            <\/div>                                                                                                                        \r\n                                                                                                                                                                                                                                                                                                                                                                                                    \r\n            <div id=\"author-affiliation\">                                                                                                \r\n                                                                                                                                        \r\n                <strong>The Heart Center of the First Hospital of Lanzhou University, and the Key Laboratory of Cardiovascular Diseases of Gansu Province, Lanzhou, China\r\n<\/strong>    <br \/>                                                                            \r\n                                                                                                                                        \r\nYu Peng, MD<br \/>\r\nZheng Zhang, MD<br \/><br \/>\r\n                [soshsc hide=\"logged\"]\r\n                <strong>You need to be <a style=\"color: #c80c44;\" href=\"https:\/\/cvja.co.za\/journal\/member-login\/\" target=\"_blank\" rel=\"noopener\">logged in to view and download<\/a> the full text PDF version. <a style=\"color: #c80c44;\" href=\"https:\/\/cvja.co.za\/journal\/register\/\" target=\"_blank\" rel=\"noopener\">Register for a free account?<\/a><\/strong> <br \/><br \/>[\/soshsc]\r\n                \r\n                \r\n                \r\n                <\/div>\r\n    \r\n<\/div>","protected":false},"excerpt":{"rendered":"<p>The aim of this study was to investigate the predictive value of the triglyceride\u2013glucose (TyG) index to assess the severity and major adverse cardiovascular events (MACE) of patients in hospital with premature coronary artery disease (PCAD).  A total of 300 patients with PCAD, diagnosed by coronary angiography (CAG), were enrolled in this study.<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[44,95],"tags":[],"class_list":["post-4389","post","type-post","status-publish","format-standard","hentry","category-cardiovascular-topics","category-volume-35-issue-4"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The predictive value of triglyceride\u2013glucose index for assessing the severity and MACE of premature coronary artery disease - Cardiovascular Journal of Africa<\/title>\n<meta name=\"description\" content=\"The aim of this study was to investigate the predictive value of the triglyceride\u2013glucose (TyG) index to assess the severity and major adverse cardiovascular events (MACE) of patients in hospital with premature coronary artery disease (PCAD).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cvja.co.za\/journal\/cvja-2023-060\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The predictive value of triglyceride\u2013glucose index for assessing the severity and MACE of premature coronary artery disease - 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