{"id":4398,"date":"2025-04-29T14:13:54","date_gmt":"2025-04-29T12:13:54","guid":{"rendered":"https:\/\/cvja.co.za\/journal\/?p=4398"},"modified":"2025-06-09T18:24:45","modified_gmt":"2025-06-09T16:24:45","slug":"cvja-2024-005","status":"publish","type":"post","link":"https:\/\/cvja.co.za\/journal\/cvja-2024-005\/","title":{"rendered":"The temporal relationship between body composition and cardiometabolic profiles in an HIV-infected (on antiretroviral therapy) versus HIV-free Western Cape study population"},"content":{"rendered":"
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\r\n \r\n Yushra Dinnie, Frans Everson, Festus M Kamau, Ingrid Webster, Boipelo Kgokane, Patrick De Boever, Nandu Goswami, Hans Strijdom \r\n <\/div> \r\n<\/div> \r\n
\r\n Copyright:<\/strong> Clinics Cardive Publishing (Pty) Ltd. publisher\r\n of Cardiovascular Journal of Africa.<\/div>\r\n
<\/div> \r\n
\r\n
\r\n Abstract \r\n <\/div> \r\n \r\n
\r\n \r\n \r\n \r\n \r\n \r\n Cardiovascular risk is a health concern in people living with HIV\/AIDS (PLWH). This longitudinal study (baseline vs 36 months) aimed to investigate the relationship between body composition and markers of cardiovascular risk in a South African study population [HIV free, n = 22 vs HIV positive on antiretroviral therapy (HIV+ART), n = 73)]. Health questionnaires, anthropometric measurements, biochemical analyses and flow-mediated dilation were performed. Linear mixedmodel statistical analyses were applied. The HIV+ART vs the HIV-free groups were independently associated with body mass index (BMI) [\u20134.92 (\u20137.99 to \u20131.84), p = 0.002] and waist circumference [\u201310.5 (\u201317.2 to \u20133.77), p = 0.003]. ART duration was associated with BMI [2.60 (0.57\u20134.62), p = 0.013], waist circumference [3.83 (0.03\u20137.63), p = 0.048] and highdensity lipoprotein cholesterol [20.18 (2.37\u201341.09), p = 0.025]. The data showed that intricate relationships existed in this study population between HIV, ART, body composition and cardiometabolic variables. There is a need for more research investigating cardiovascular risk in PLWH, particularly in the context of changes in body composition measures. \r\n
\r\n \r\n <\/div> \r\n <\/div> \r\n \r\n \r\n
\r\n \r\n Keywords:<\/strong> \r\n \r\n body composition, body mass index, waist circumference, HIV\/AIDS, cardiovascular risk, antiretroviral therapy<\/strong> \r\n \r\n <\/div> \r\n \r\n
\r\n \r\n Submitted:<\/strong> October 15, 2023; \r\n Accepted:<\/strong> February 20, 2024; \r\n Published Online First:<\/strong> April 05, 2024; \r\n Published:<\/strong> December 15, 2024 \r\n
\r\n Cardiovasc J Afr 2024; 35<\/b>: 416-424<\/em>\r\n
Volume 35, Issue 4<\/strong>
\r\n \r\n <\/div> \r\n \r\n
\r\n DOI Citation Reference: dx.doi.org\/10.5830\/CVJA-2024-005 \r\n <\/div> \r\n \r\n
\r\n \r\n Centre for Cardio-metabolic Research in Africa, Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa\r\n<\/strong>
\r\n \r\n Yushra Dinnie, BSc Hons
\r\nFrans Everson, PhD
\r\nFestus M Kamau, MD, PhD
\r\nIngrid Webster, PhD
\r\nBoipelo Kgokane, MSc
\r\nHans Strijdom, MD, PhD
\r\n \r\n <\/div> \r\n \r\n
\r\n \r\n Centre for Environmental Sciences, Hasselt University, Diepenbeek; Antwerp University Hospital, Edegem, Belgium<\/strong>
\r\n \r\n Patrick De Boever, PhD
\r\n \r\n <\/div> \r\n \r\n
\r\n \r\n Division of Physiology, Otto Loewi Research Center of Vascular Biology, Immunity and Inflammation, Medical University of Graz, Graz, Austria; and College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates<\/strong>
\r\n \r\n Nandu Goswami, MD, PhD

\r\n [soshsc hide=\"logged\"]\r\n You need to be logged in to view and download<\/a> the full text PDF version. Register for a free account?<\/a><\/strong>

[\/soshsc]\r\n \r\n \r\n \r\n <\/div>\r\n \r\n<\/div>","protected":false},"excerpt":{"rendered":"

Cardiovascular risk is a health concern in people living with HIV\/AIDS (PLWH). This longitudinal study (baseline vs 36 months) aimed to investigate the relationship between body composition and markers of cardiovascular risk in a South African study population [HIV free, n = 22 vs HIV positive on antiretroviral therapy (HIV+ART), n = 73)]. Health questionnaires, anthropometric measurements, biochemical analyses and flow-mediated dilation were performed.<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[44,95],"tags":[],"class_list":["post-4398","post","type-post","status-publish","format-standard","hentry","category-cardiovascular-topics","category-volume-35-issue-4"],"yoast_head":"\nThe temporal relationship between body composition and cardiometabolic profiles in an HIV-infected (on antiretroviral therapy) versus HIV-free Western Cape study population - Cardiovascular Journal of Africa<\/title>\n<meta name=\"description\" content=\"Cardiovascular risk is a health concern in people living with HIV\/AIDS (PLWH). 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