{"id":4953,"date":"2025-06-30T14:10:11","date_gmt":"2025-06-30T12:10:11","guid":{"rendered":"https:\/\/cvja.co.za\/journal\/?p=4953"},"modified":"2025-07-01T16:55:40","modified_gmt":"2025-07-01T14:55:40","slug":"cvja-2025-021","status":"publish","type":"post","link":"https:\/\/cvja.co.za\/journal\/cvja-2025-021\/","title":{"rendered":"Platelet-to-Haemoglobin Ratio Predicts the Development of Left Ventricular Apical Thrombus"},"content":{"rendered":"
\r\n
\r\n
\r\n \r\n Engin Alg\u00fcl, Nail Burak \u00d6zbeyaz, Haluk Furkan S\u00b8 ahan, Faruk Ayd\u0131ny\u0131lmaz, Hamza Sunman, Tolga Han Efe, \u00d6zcan \u00d6zdemir \r\n <\/div> \r\n<\/div> \r\n
\r\n Copyright:<\/strong> Clinics Cardive Publishing (Pty) Ltd. publisher\r\n of Cardiovascular Journal of Africa.<\/div>\r\n
<\/div> \r\n
\r\n
\r\n Abstract \r\n <\/div> \r\n \r\n
\r\n \r\n \r\n \r\n \r\n Objective:<\/strong> \r\n \r\n Apical thrombus (AT) is a severe complication in myocardial infarction (MI), increasing the risk of thromboembolic events. Platelet-to-haemoglobin ratio (PHR) is a novel, inexpensive predictor of cardiovascular outcomes. This study explores the association between PHR and AT in MI patients. \r\n
\r\n \r\n Materials & methods:<\/strong> \r\n \r\n This retrospective study included 690 anterior MI patients (314 patients with AT and 376 patients without AT as a control group). Blood samples were analysed to calculate PHR, and echocardiographic evaluations identified AT. Logistic regression and ROC analysis determined independent predictors and the optimal PHR cut-off value for AT. \r\n
\r\n \r\n Results:<\/strong> \r\n \r\n PHRwas significantly higher in theAT group (2.03\u00b1 0.64 vs. 1.85\u00b10.50; p<0.001). Multivariate analysis identified PHR, proximal LAD lesions, and lower LVEF as independent predictors. The PHR cut-off of 1.88 showed 69.3% sensitivity and 68.4% specificity. \r\n
\r\n \r\n Conclusion:<\/strong> \r\n \r\n PHR is a simple, accessible marker for predicting AT inMI patients. Its use may improve early risk stratification and clinical outcomes. \r\n
\r\n \r\n <\/div> \r\n <\/div> \r\n \r\n \r\n
\r\n \r\n Keywords:<\/strong> \r\n \r\n apical thrombus, myocardial infarction, platelet-tohaemoglobin ratio<\/strong> \r\n \r\n <\/div> \r\n \r\n
\r\n \r\n Submitted:<\/strong> May 18, 2024; \r\n Accepted:<\/strong> December 9, 2024; \r\n Published:<\/strong> June 30, 2025
\r\n Cardiovasc J Afr 2025; 36<\/b>: 191-195<\/em>\r\n
Volume 36, Issue 2<\/strong>
\r\n <\/div> \r\n \r\n
\r\n DOI Citation Reference: dx.doi.org\/10.5830\/CVJA-2025-021 \r\n <\/div> \r\n \r\n
\r\n \r\n Etlik City Hospital, Department of Cardiology, Ankara, Turkey<\/strong>
\r\n \r\n Engin Alg\u00fcl
\r\nHaluk Furkan Sahan
\r\nHamza Sunman
\r\nTolga Han Efe
\r\n\u00d6zcan \u00d6zdemir
\r\nLezelle Botes, DTech, PhD
\r\n \r\n \r\n \r\n \r\n <\/div> \r\n \r\n
\r\n \r\n Ankara University, Department of Cardiology, Ankara, Turkey<\/strong>
\r\n \r\n Nail Burak \u00d6zbeyaz
\r\n \r\n <\/div> \r\n \r\n
\r\n \r\n University of Health Sciences, Erzurum Education and Research Hospital, Department of Cardiology, Erzurum, Turkey<\/strong>
\r\n \r\n Faruk Ayd\u0131ny\u0131lmaz

\r\n\r\n [soshsc hide=\"logged\"]\r\n You need to be logged in to view and download<\/a> the full text PDF version. Register for a free account?<\/a><\/strong>

[\/soshsc]\r\n \r\n \r\n \r\n <\/div>\r\n \r\n<\/div>","protected":false},"excerpt":{"rendered":"

Apical thrombus (AT) is a severe complication in myocardial infarction (MI), increasing the risk of thromboembolic events. Platelet-to-haemoglobin ratio (PHR) is a novel, inexpensive predictor of cardiovascular outcomes. This study explores the association between PHR and AT in MI patients. This retrospective study included 690 anterior MI patients (314 patients with AT and 376 patients without AT as a control group). <\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[44,101],"tags":[],"class_list":["post-4953","post","type-post","status-publish","format-standard","hentry","category-cardiovascular-topics","category-volume-36-issue-2"],"yoast_head":"\nPlatelet-to-Haemoglobin Ratio Predicts the Development of Left Ventricular Apical Thrombus - Cardiovascular Journal of Africa<\/title>\n<meta name=\"description\" content=\"Apical thrombus (AT) is a severe complication in myocardial infarction (MI), increasing the risk of thromboembolic events.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cvja.co.za\/journal\/cvja-2025-021\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Platelet-to-Haemoglobin Ratio Predicts the Development of Left Ventricular Apical Thrombus - 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