{"id":5033,"date":"2025-07-29T14:29:58","date_gmt":"2025-07-29T12:29:58","guid":{"rendered":"https:\/\/cvja.co.za\/journal\/?p=5033"},"modified":"2025-07-29T14:29:58","modified_gmt":"2025-07-29T12:29:58","slug":"cvja-2025-007","status":"publish","type":"post","link":"https:\/\/cvja.co.za\/journal\/cvja-2025-007\/","title":{"rendered":"Early and mid-term outcomes of patients undergoing cardiac surgery for infective endocarditis"},"content":{"rendered":"
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\r\n \r\n \r\nMuhammet Selim Ya\u015far, Emre K\u00fclahcio\u011flu, Ay\u015fe Nur Do\u011fmu\u015f, Ay\u015fe Yasemin Tezer-Tek\u00e7e, \u015eeref Alp K\u00fc\u00e7\u00fcker \r\n <\/div> \r\n<\/div> \r\n
\r\n Copyright:<\/strong> Clinics Cardive Publishing (Pty) Ltd. publisher\r\n of Cardiovascular Journal of Africa.<\/div>\r\n
<\/div> \r\n
\r\n
\r\n Abstract \r\n <\/div> \r\n \r\n
\r\n \r\n \r\n \r\n \r\n Aim:<\/strong> \r\n \r\n Infective endocarditis remains a serious condition with a high mortality rate. However, surgical treatment of infective endocarditis still raises some questions despite the researches. This study aimed to analyse the early- and mid-term outcomes of patients with infective endocarditis who required surgical treatment and to identify perioperative risk factors for mortality and morbidity. \r\n
\r\n \r\n Methods:<\/strong> \r\n \r\n Between April 2019 and January 2024, 70 patients who were diagnosed with infective endocarditis according to the Modified Duke criteria and underwent cardiac surgery in our clinic, retrospectively. \r\n
\r\n\t\t\t\t\r\n\t\t\t\tResults:<\/strong> \r\n \r\n The results showed that in the preoperative period, older age, previous surgery\/intervention, and chronic renal failure were associated with higher mortality in the postoperative period. Long cross-clamp and cardiopulmonary bypass times increased the mortality as the complexity of the intraoperative case increased. Patients requiring postoperative mechanical and inotropic support had a worse prognosis (p<0.05). \r\n
\r\n \r\n \r\n Conclusion:<\/strong> \r\n \r\n The present study identified potential genetic markers increasing susceptibility\/risk of MI in the study population. Our study provides a platform for future large scale genetic studies and identifying individuals who at risk of developing MI. The present study emphasise the development of treatments strategies based on genetic make- up of individual. \r\n
\r\n\t\t\t\t\r\n\t\t\t\t Glossary of Abbreviations:<\/strong> \r\n \r\n IE: Infective Endocarditis, CT: Computed Tomography, CABG: Coronary Artery Bypass Grafting, AVR: Aortic Valve Replacement, MVR: Mitral Valve Replacement, TVR: Tricuspid Valve Replacement, PVR: Pulmonary Valve Replacement, MBVP: Mitral Balloon Valvuloplasty, ECMO: Extracorporeal Membrane Oxygenation, IABP: Intraaortic Balloon Pump, MAIF: Mitral-aortic intervalvular fibrosa, CPB: Cardiopulmonary Bypass, CPR: Cardiopulmonary Resuscitation. \r\n
\r\n\r\n \r\n <\/div> \r\n <\/div> \r\n \r\n \r\n
\r\n \r\n Keywords:<\/strong> \r\n \r\n Infective Endocarditis, Cardiac surgery<\/strong> \r\n \r\n <\/div> \r\n \r\n
\r\n \r\n Submitted:<\/strong> November 29, 2024; \r\n Accepted:<\/strong> January 30, 2025; \r\n Published:<\/strong> June 30, 2025
\r\n Cardiovasc J Afr 2025; 36<\/b>: 102-109<\/em>\r\n
Volume 36, Issue 2<\/strong>
\r\n <\/div> \r\n \r\n
\r\n DOI Citation Reference: dx.doi.org\/10.5830\/CVJA-2025-007 \r\n <\/div> \r\n \r\n\t\t\t\t
\r\n \r\n Mardin Education and Research Hospital, M.D. Department of Cardiovascular Surgery, Mardin, Turkey\r\n<\/strong>
\r\n\t\t\t\tMuhammet Selim Ya\u015far, M.D.\r\n

\r\n\r\n Kilis Prof. Dr. Alaeddin Yava\u015fca State Hospital, M.D. Department of Cardiovascular Surgery, Kilis, Turkey \r\n\r\n<\/strong>
\r\n\t\t\t\tEmre K\u00fclahcio\u011flu, M.D.\r\n\r\n

\r\n\r\n Ankara Bilkent City Hospital, Department of Cardiovascular Surgery, Ankara, Turkey\r\n\r\n<\/strong>
\r\n\t\t\t\tAy\u015fe Nur Do\u011fmu\u015f, M.D.
\r\n\u015eeref Alp K\u00fc\u00e7\u00fcker, M.D.\r\n

\r\n\r\n Ankara Bilkent City Hospital, Department of Infectious Diseases and Clinical Microbiology, Ankara, Turkey\r\n \r\n<\/strong>
\r\n\t\t\t\tAy\u015fe Yasemin Tezer-Tek\u00e7e, M.D.\r\n
\r\n \r\n\r\n
\r\n\r\n [soshsc hide=\"logged\"]\r\n You need to be logged in to view and download<\/a> the full text PDF version. Register for a free account?<\/a><\/strong>

[\/soshsc]\r\n \r\n \r\n \r\n <\/div>\r\n \r\n<\/div>","protected":false},"excerpt":{"rendered":"

Infective endocarditis remains a serious condition with a high mortality rate. However, surgical treatment of infective endocarditis still raises some questions despite the researches. 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