{"id":5048,"date":"2025-08-05T11:35:44","date_gmt":"2025-08-05T09:35:44","guid":{"rendered":"https:\/\/cvja.co.za\/journal\/?p=5048"},"modified":"2025-08-05T11:35:44","modified_gmt":"2025-08-05T09:35:44","slug":"cvja-2025-006","status":"publish","type":"post","link":"https:\/\/cvja.co.za\/journal\/cvja-2025-006\/","title":{"rendered":"Is there a relationship between the index of electrophysiological balance and newly diagnosed atrial fibrillation in ischemic stroke patients?"},"content":{"rendered":"
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\r\n \r\n \r\n\r\nBayram Ba\u011f\u0131rtan, Song\u00fcl Usalp, \u00d6nder Demir\u00f6z, Ali Bayraktar, Behzat \u00d6zdemir, Kanber \u00d6cal Karabay \r\n <\/div> \r\n<\/div> \r\n
\r\n Copyright:<\/strong> Clinics Cardive Publishing (Pty) Ltd. publisher\r\n of Cardiovascular Journal of Africa.<\/div>\r\n
<\/div> \r\n
\r\n
\r\n Abstract \r\n <\/div> \r\n \r\n
\r\n \r\n \r\n \r\n \r\n Objective:<\/strong> \r\n \r\n The objective of this study was to investigate the association between the index of electrophysiological balance (iCEB) and ischaemic stroke (IS) and newly diagnosed atrial fibrillation (AF). AF is an independent risk factor for stroke. Study design: This is an observational study. Place and duration of the study: The study was conducted at the institution where the authors are employed (\u015eehit Prof Dr \u0130lhan Varank Training and Research Hospital, Istanbul, between 1 October 2021 and 1 April 2022). \r\n
\r\n \r\n Methodology:<\/strong> \r\n \r\n We included 452 patients in this study diagnosed with IS. The patients participating in the research were separated into two categories: patients with and without AF on rhythm holter. Both groups were balanced in point of clinical, demographic, and echocardiographic features. iCEB was described and evaluated as the proportion of QT to QRS (QT\/QRS); and ciCEB (QTc\/QRS). A p-value under 0.05 was noted as significant. \r\n
\r\n\t\t\t\t\r\n\t\t\t\tResults:<\/strong> \r\n \r\n The mean old of the participants in the AF group (n = 250) was 72.4 \u00b1 9.5 years but the control group (n = 202) was 62.1 \u00b1 12.6) years (p < 0.001). Both groups were similar in point of demographic and clinical features. CHA2DS2-VASC score (5.2 \u00b1 1.5 vs 4.3 \u00b1 1.3, p < 0.001), QT duration (412.3 \u00b1 48.1 vs 404.5 \u00b1 41.5 ms, p = 0.029), cQT duration (456.3\r\n35.4 vs 441.9 \u00b1 33.2 ms, p = 0.017), iCEB (4.4 \u00b1 0.7 vs 4.1 \u00b1 0.6 ms, p = 0.007), ciCEB (4.9 \u00b1 0.8 vs 4.6 \u00b1 0.4 ms, p = 0.005) were higher in the AF group. Multivariable analyses confirmed that only age (OR: 1.075, 95%CI [1.058-1.107], p < 0.001) and the iCEB (OR:1.781, 95%CI [1.128- 2.812], p = 0.013) are potential independent risk factors for AF events with ischaemic stroke patients. \r\n
\r\n \r\n \r\n Conclusion:<\/strong> \r\n \r\n The study concluded with the finding that iCEB and ciCEB values were elevated in patients who presented with IS and AF events detected on rhythm Holter. Concurrently, these patients exhibited higher CHA2DS2-VASc scores and advanced age. Furthermore, the iCEB parameter was found to be a valuable predictor of AF in patients with ischaemic stroke and normal sinus rhythm. \r\n
\r\n\r\n \r\n <\/div> \r\n <\/div> \r\n \r\n \r\n
\r\n \r\n Keywords:<\/strong> \r\n \r\n ischaemic stroke, atrial fibrillation, electrocardiography arrhythmia<\/strong> \r\n \r\n <\/div> \r\n \r\n
\r\n \r\n Submitted:<\/strong> November 23, 2024; \r\n Accepted:<\/strong> March 5, 2025; \r\n Published:<\/strong> June 30, 2025
\r\n Cardiovasc J Afr 2025; 36<\/b>: 96-101<\/em>\r\n
Volume 36, Issue 2<\/strong>
\r\n <\/div> \r\n \r\n
\r\n DOI Citation Reference: dx.doi.org\/10.5830\/CVJA-2025-006 \r\n <\/div> \r\n \r\n\t\t\t\t
\r\n \r\n Department of Cardiology, Sancaktepe Sehit Professor Doctor Ilhan Varank Training and Research Hospital, Istanbul, Turkey\r\n<\/strong>
\r\n\t\t\t\tBayram Ba\u011f\u0131rtan
\r\n\u00d6nder Demir\u00f6z
\r\nAli Bayraktar
\r\nBehzat \u00d6zdemir
\r\nKanber \u00d6cal Karabay\r\n

\r\n\r\n Department of Cardiology, University of Health Sciences Kosuyolu Training and Research Hospital, \u0130stanbul, Turkey\r\n\r\n<\/strong>
\r\nSong\u00fcl Usalp\r\n\r\n

\r\n \r\n\r\n [soshsc hide=\"logged\"]\r\n You need to be logged in to view and download<\/a> the full text PDF version. Register for a free account?<\/a><\/strong>

[\/soshsc]\r\n \r\n \r\n \r\n <\/div>\r\n \r\n<\/div>","protected":false},"excerpt":{"rendered":"

The objective of this study was to investigate the association between the index of electrophysiological balance (iCEB) and ischaemic stroke (IS) and newly diagnosed atrial fibrillation (AF). AF is an independent risk factor for stroke. Study design: This is an observational study. 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