{"id":5077,"date":"2025-09-03T10:12:03","date_gmt":"2025-09-03T08:12:03","guid":{"rendered":"https:\/\/cvja.co.za\/journal\/?p=5077"},"modified":"2026-05-05T13:24:14","modified_gmt":"2026-05-05T11:24:14","slug":"cvja-2025-034","status":"publish","type":"post","link":"https:\/\/cvja.co.za\/journal\/cvja-2025-034\/","title":{"rendered":"Effect of cancer on long-term survival after cardiac surgery"},"content":{"rendered":"
\r\n
\r\n
\r\n \r\n \r\nAksoy Tamer, Arslan Ahmet Hulisi, Ustunsoy Hasim \r\n <\/div> \r\n<\/div> \r\n
\r\n Copyright:<\/strong> Clinics Cardive Publishing (Pty) Ltd. publisher\r\n of Cardiovascular Journal of Africa.<\/div>\r\n
<\/div> \r\n
\r\n
\r\n Abstract \r\n <\/div> \r\n \r\n
\r\n \r\n \r\n \r\n \r\n Background:<\/strong> \r\n \r\n The prevalence of patients requiring cardiac surgery with concurrent active cancer or a history of cancer is rising. This study aimed to evaluate the differences in post- cardiac surgery long-term survival between these patients and those without cancer and to identify the factors influencing survival. \r\n
\r\n \r\n Methods:<\/strong> \r\n \r\n This retrospective study included 38 patients with active cancer or a history of cancer (Group 1) and 45 patients without cancer (Group 2) who underwent cardiac surgery. Demographical and perioperative clinical data of the patients were retrieved from electronic patient records. Patients\/relatives were contacted by phone to check their survival status. \r\n
\r\n\t\t\t\t\r\n\t\t\t\tResults:<\/strong> \r\n \r\n Postoperative in-hospital mortality was 5.3% (2\/38) and 0.0% (0\/45) in the Group 1 and Group 2, respectively (p = 0.207). The mean survival was significantly shorter for Group 1 when compared to Group 2 (93.6 \u00b1 11.6 [95% CI, 70.8- 116.4] vs. 156.8\u00b19.7 months [95% CI, 137.7-175.9], p<0.001). Multivariate analysis identified the presence of cancer (HR: 7.7, 95% CI: 1.6-36.8, p = 0.010), hospitalisation longer than one week (HR: 4.2, 95% CI: 1.2-14.9, p = 0.028), and fresh frozen plasma need (HR: 7.0, 95% CI: 1.8-27.5, p = 0.006) as significant independent predictors of worse survival outcome. \r\n
\r\n \r\n \r\n Conclusion:<\/strong> \r\n \r\n Patients with a history of cancer or active cancer can be operated with acceptable risk. The findings of this study suggest that cancer affects long-term survival after cardiac surgery, primarily due to cancer progression. It emphasises the need for a multidisciplinary approach to balance benefits of cardiac surgery with the prognosis of cancer and underlines the importance of future research for better clinical decision- making in these patients. \r\n
\r\n\r\n \r\n <\/div> \r\n <\/div> \r\n \r\n \r\n
\r\n \r\n Keywords:<\/strong> \r\n \r\n cardiac surgery, cancer, survival<\/strong> \r\n \r\n <\/div> \r\n \r\n
\r\n \r\n Submitted:<\/strong> June 3, 2024; \r\n Accepted:<\/strong> February 25, 2025; \r\n Published:<\/strong> September 3, 2025
\r\n Cardiovasc J Afr 2025; 36<\/b>: 250-255<\/em>\r\n
Volume 36, Issue 3<\/strong>
\r\n <\/div> \r\n \r\n
\r\n DOI Citation Reference: dx.doi.org\/10.5830\/CVJA-2025-034 \r\n <\/div> \r\n \r\n\t\t\t\t
\r\n \r\n Department of Anaesthesiology and Reanimation, Anadolu Medical Center, Kocaeli, Turkey\r\n<\/strong>
\r\n\t\t\t\tAksoy Tamer\r\n

\r\n\r\n Department of Cardiovascular Surgery, Anadolu Medical Center, Kocaeli, Turkey\r\n\r\n<\/strong>
\r\nArslan Ahmet Hulisi
\r\nUstunsoy Hasim\r\n\r\n

\r\n \r\n\r\n [soshsc hide=\"logged\"]\r\n You need to be logged in to view and download<\/a> the full text PDF version. Register for a free account?<\/a><\/strong>

[\/soshsc]\r\n \r\n \r\n \r\n <\/div>\r\n \r\n<\/div>","protected":false},"excerpt":{"rendered":"

The prevalence of patients requiring cardiac surgery with concurrent active cancer or a history of cancer is rising. This study aimed to evaluate the differences in post- cardiac surgery long-term survival between these patients and those without cancer and to identify the factors influencing survival.<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[44,107],"tags":[],"class_list":["post-5077","post","type-post","status-publish","format-standard","hentry","category-cardiovascular-topics","category-volume-36-issue-3"],"yoast_head":"\nEffect of cancer on long-term survival after cardiac surgery - Cardiovascular Journal of Africa<\/title>\n<meta name=\"description\" content=\"The prevalence of patients requiring cardiac surgery with concurrent active cancer or a history of cancer is rising. This study aimed to evaluate the differences in post- cardiac surgery long-term survival between these patients and those without cancer and to identify the factors influencing survival.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cvja.co.za\/journal\/cvja-2025-034\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Effect of cancer on long-term survival after cardiac surgery - Cardiovascular Journal of Africa\" \/>\n<meta property=\"og:description\" content=\"The prevalence of patients requiring cardiac surgery with concurrent active cancer or a history of cancer is rising. This study aimed to evaluate the differences in post- cardiac surgery long-term survival between these patients and those without cancer and to identify the factors influencing survival.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cvja.co.za\/journal\/cvja-2025-034\/\" \/>\n<meta property=\"og:site_name\" content=\"Cardiovascular Journal of Africa\" \/>\n<meta property=\"article:published_time\" content=\"2025-09-03T08:12:03+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-05-05T11:24:14+00:00\" \/>\n<meta name=\"author\" content=\"Jaco Moolman\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jaco Moolman\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/cvja.co.za\/journal\/cvja-2025-034\/\",\"url\":\"https:\/\/cvja.co.za\/journal\/cvja-2025-034\/\",\"name\":\"Effect of cancer on long-term survival after cardiac surgery - Cardiovascular Journal of Africa\",\"isPartOf\":{\"@id\":\"https:\/\/cvja.co.za\/journal\/#website\"},\"datePublished\":\"2025-09-03T08:12:03+00:00\",\"dateModified\":\"2026-05-05T11:24:14+00:00\",\"author\":{\"@id\":\"https:\/\/cvja.co.za\/journal\/#\/schema\/person\/6bf8a30a039e93fd8112db707affb920\"},\"description\":\"The prevalence of patients requiring cardiac surgery with concurrent active cancer or a history of cancer is rising. This study aimed to evaluate the differences in post- cardiac surgery long-term survival between these patients and those without cancer and to identify the factors influencing survival.\",\"breadcrumb\":{\"@id\":\"https:\/\/cvja.co.za\/journal\/cvja-2025-034\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/cvja.co.za\/journal\/cvja-2025-034\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/cvja.co.za\/journal\/cvja-2025-034\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/cvja.co.za\/journal\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Effect of cancer on long-term survival after cardiac surgery\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/cvja.co.za\/journal\/#website\",\"url\":\"https:\/\/cvja.co.za\/journal\/\",\"name\":\"Cardiovascular Journal of Africa\",\"description\":\"The Cardiovascular Journal of Africa is a peer-reviewed medical journal publishing leading research in cardiovascular health across Africa since 1990\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/cvja.co.za\/journal\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/cvja.co.za\/journal\/#\/schema\/person\/6bf8a30a039e93fd8112db707affb920\",\"name\":\"Jaco Moolman\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/cvja.co.za\/journal\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/454c6719ed785bfd40e036ca3c3ac3347c56b4a99902df8beb62d882b1e6967f?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/454c6719ed785bfd40e036ca3c3ac3347c56b4a99902df8beb62d882b1e6967f?s=96&d=mm&r=g\",\"caption\":\"Jaco Moolman\"},\"url\":\"https:\/\/cvja.co.za\/journal\/author\/jacodesignconnection-co-za\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Effect of cancer on long-term survival after cardiac surgery - Cardiovascular Journal of Africa","description":"The prevalence of patients requiring cardiac surgery with concurrent active cancer or a history of cancer is rising. This study aimed to evaluate the differences in post- cardiac surgery long-term survival between these patients and those without cancer and to identify the factors influencing survival.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/cvja.co.za\/journal\/cvja-2025-034\/","og_locale":"en_US","og_type":"article","og_title":"Effect of cancer on long-term survival after cardiac surgery - Cardiovascular Journal of Africa","og_description":"The prevalence of patients requiring cardiac surgery with concurrent active cancer or a history of cancer is rising. This study aimed to evaluate the differences in post- cardiac surgery long-term survival between these patients and those without cancer and to identify the factors influencing survival.","og_url":"https:\/\/cvja.co.za\/journal\/cvja-2025-034\/","og_site_name":"Cardiovascular Journal of Africa","article_published_time":"2025-09-03T08:12:03+00:00","article_modified_time":"2026-05-05T11:24:14+00:00","author":"Jaco Moolman","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jaco Moolman","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/cvja.co.za\/journal\/cvja-2025-034\/","url":"https:\/\/cvja.co.za\/journal\/cvja-2025-034\/","name":"Effect of cancer on long-term survival after cardiac surgery - Cardiovascular Journal of Africa","isPartOf":{"@id":"https:\/\/cvja.co.za\/journal\/#website"},"datePublished":"2025-09-03T08:12:03+00:00","dateModified":"2026-05-05T11:24:14+00:00","author":{"@id":"https:\/\/cvja.co.za\/journal\/#\/schema\/person\/6bf8a30a039e93fd8112db707affb920"},"description":"The prevalence of patients requiring cardiac surgery with concurrent active cancer or a history of cancer is rising. This study aimed to evaluate the differences in post- cardiac surgery long-term survival between these patients and those without cancer and to identify the factors influencing survival.","breadcrumb":{"@id":"https:\/\/cvja.co.za\/journal\/cvja-2025-034\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/cvja.co.za\/journal\/cvja-2025-034\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/cvja.co.za\/journal\/cvja-2025-034\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/cvja.co.za\/journal\/"},{"@type":"ListItem","position":2,"name":"Effect of cancer on long-term survival after cardiac surgery"}]},{"@type":"WebSite","@id":"https:\/\/cvja.co.za\/journal\/#website","url":"https:\/\/cvja.co.za\/journal\/","name":"Cardiovascular Journal of Africa","description":"The Cardiovascular Journal of Africa is a peer-reviewed medical journal publishing leading research in cardiovascular health across Africa since 1990","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/cvja.co.za\/journal\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/cvja.co.za\/journal\/#\/schema\/person\/6bf8a30a039e93fd8112db707affb920","name":"Jaco Moolman","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/cvja.co.za\/journal\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/454c6719ed785bfd40e036ca3c3ac3347c56b4a99902df8beb62d882b1e6967f?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/454c6719ed785bfd40e036ca3c3ac3347c56b4a99902df8beb62d882b1e6967f?s=96&d=mm&r=g","caption":"Jaco Moolman"},"url":"https:\/\/cvja.co.za\/journal\/author\/jacodesignconnection-co-za\/"}]}},"_links":{"self":[{"href":"https:\/\/cvja.co.za\/journal\/wp-json\/wp\/v2\/posts\/5077","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cvja.co.za\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cvja.co.za\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cvja.co.za\/journal\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/cvja.co.za\/journal\/wp-json\/wp\/v2\/comments?post=5077"}],"version-history":[{"count":1,"href":"https:\/\/cvja.co.za\/journal\/wp-json\/wp\/v2\/posts\/5077\/revisions"}],"predecessor-version":[{"id":5485,"href":"https:\/\/cvja.co.za\/journal\/wp-json\/wp\/v2\/posts\/5077\/revisions\/5485"}],"wp:attachment":[{"href":"https:\/\/cvja.co.za\/journal\/wp-json\/wp\/v2\/media?parent=5077"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cvja.co.za\/journal\/wp-json\/wp\/v2\/categories?post=5077"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cvja.co.za\/journal\/wp-json\/wp\/v2\/tags?post=5077"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}