{"id":5167,"date":"2025-10-09T09:09:42","date_gmt":"2025-10-09T07:09:42","guid":{"rendered":"https:\/\/cvja.co.za\/journal\/?p=5167"},"modified":"2026-05-14T11:31:29","modified_gmt":"2026-05-14T09:31:29","slug":"cvja-2025-059","status":"publish","type":"post","link":"https:\/\/cvja.co.za\/journal\/cvja-2025-059\/","title":{"rendered":"Delta perfusion rate predicts the development of adverse outcome in cardiopulmonary bypass patients"},"content":{"rendered":"
\r\n
\r\n
\r\n \r\n \r\nBi\u015far Ama\u00e7, Mustafa Abanoz, Mesut Engin \r\n <\/div> \r\n<\/div> \r\n
\r\n Copyright:<\/strong> Clinics Cardive Publishing (Pty) Ltd. publisher\r\n of Cardiovascular Journal of Africa.<\/div>\r\n
<\/div> \r\n
\r\n
\r\n Abstract \r\n <\/div> \r\n \r\n
\r\n \r\n \r\n \r\n \r\n Introduction:<\/strong> \r\n \r\nDespite the advances in CPB, various complications may occur. Prediction and anticipation of these undesirable outcomes is of great importance. For this reason, various markers have been tried to be determined. \r\n
\r\n \r\n Objective:<\/strong> \r\n \r\nThe aim of this retrospective study was to evaluate whether the delta perfusion ratio, i.e. (v-a)CO2\/(a- v)O2 ratio, and other perfusion markers are good indices for predicting adverse postoperative outcomes in patients undergoing cardiac surgery with CPB. \r\n
\r\n \r\n Methods:<\/strong> \r\n \r\nThis study retrospectively included data from 169 adult patients aged 20 to 85 years who underwent consecutive CPB-guided isolated CABG surgery after applying exclusion criteria. Perfusion indices were compared between patients with and without adverse outcomes after CPB. \r\n
\r\n \r\n Results:<\/strong> \r\nThere was a statistically significant correlation between the (v-a)CO2\/(a-v)O2 ratio at CPB output and ICU admission (p<0.001; p = 0.004, respectively); Scv02 and CO2 deficit after ACC and at CPB output and adverse outcomes after CPB (p = 0.010; p = 0.007; p = 0.000; p = 0.008, respectively). In ROC curve analysis, the cut- off value for CPB output (v-a)CO2\/(a-v)O2 value was 2.27 (67.9% sensitivity, 65.9% specificity). The cut-off value for ICU entry (v-a)CO2\/(a-v)O2 value was 2.6 (62.6% sensitivity, 73.3% specificity).\r\n
\r\n \r\n \r\n Conclusion:<\/strong> \r\n \r\nThere was a statistically significant correlation between the (v-a)CO2\/(a-v)O2 ratio after CPB and at ICU admission, ScvO2 and CO2 deficit after ACC and after CPB and adverse outcomes after CPB. Therefore, we think that these are reliable perfusion indices in CPB-guided cardiac surgery. \r\n
\r\n\r\n \r\n <\/div> \r\n <\/div> \r\n \r\n \r\n
\r\n \r\n Keywords:<\/strong> \r\n \r\n Cardiopulmonary Bypass, Perfusion Indices, Veno arterial Carbon Dioxide Difference, Arterial venous Oxygen Difference, Delta Perfusion Rate<\/strong> \r\n \r\n <\/div> \r\n \r\n
\r\n \r\n Submitted:<\/strong> October 21, 2024; \r\n Accepted:<\/strong> October 29, 2024; \r\n Published:<\/strong> September 26, 2025
\r\n Cardiovasc J Afr 2025; 36<\/b>: 424-429<\/em>\r\n
Volume 36, Issue 3<\/strong>
\r\n <\/div> \r\n \r\n
\r\n DOI Citation Reference: dx.doi.org\/10.5830\/CVJA-2025-059 \r\n <\/div> \r\n \r\n
\r\n \r\n Department of Perfusion, Faculty of Health Sciences, Harran University, Sanliurfa, Turkey\r\n<\/strong>
\r\nBi\u015far Ama\u00e7\r\n

\r\n\r\n Department of Cardiovascular Surgery, Sanliurfa Mehmet Akif Inan Training and Research Hospital, University of Health Sciences, Sanliurfa, Turkey\r\n<\/strong>
\r\nMustafa Abanoz\r\n

\r\n\r\n Department of Cardiovascular Surgery, Bursa Yuksek Ihtisas Training and Research Hospital, University of Health Sciences, Bursa, Turkey\r\n\r\n<\/strong>
\r\nMesut Engin\r\n\r\n

\r\n \r\n\r\n [soshsc hide=\"logged\"]\r\n You need to be logged in to view and download<\/a> the full text PDF version. Register for a free account?<\/a><\/strong>

[\/soshsc]\r\n \r\n \r\n \r\n <\/div>\r\n \r\n<\/div>","protected":false},"excerpt":{"rendered":"

Despite the advances in CPB, various complications may occur. Prediction and anticipation of these undesirable outcomes is of great importance. For this reason, various markers have been tried to be determined. <\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[44,107],"tags":[],"class_list":["post-5167","post","type-post","status-publish","format-standard","hentry","category-cardiovascular-topics","category-volume-36-issue-3"],"yoast_head":"\nDelta perfusion rate predicts the development of adverse outcome in cardiopulmonary bypass patients - Cardiovascular Journal of Africa<\/title>\n<meta name=\"description\" content=\"Despite the advances in CPB, various complications may occur. 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