{"id":5258,"date":"2025-10-27T11:20:00","date_gmt":"2025-10-27T09:20:00","guid":{"rendered":"https:\/\/cvja.co.za\/journal\/?p=5258"},"modified":"2026-05-05T14:31:57","modified_gmt":"2026-05-05T12:31:57","slug":"cvja-2025-074","status":"publish","type":"post","link":"https:\/\/cvja.co.za\/journal\/cvja-2025-074\/","title":{"rendered":"Prevalence of occlusive myocardial infarction in patients diagnosed with non-ST-elevation myocardial infarction at a single private facility in Cape Town, South Africa"},"content":{"rendered":"
\r\n
\r\n
\r\n \r\n \r\nElmari Schoeman, Ibrahim D\u2019Andrea, Willem Stassen\r\n <\/div> \r\n<\/div> \r\n
\r\n Copyright:<\/strong> Clinics Cardive Publishing (Pty) Ltd. publisher\r\n of Cardiovascular Journal of Africa.<\/div>\r\n
<\/div> \r\n
\r\n
\r\n Abstract \r\n <\/div> \r\n \r\n
\r\n \r\n \r\n \r\n \r\n Background:<\/strong> \r\n \r\nST-elevation myocardial infarction (STEMI) is associated with acute coronary occlusion, while non-ST- elevation myocardial infarction (NSTEMI) is often associated with partial occlusion. However, 25.5% of NSTEMIS involve complete occlusion, impacting mortality and major adverse cardiovascular events (MACE). The occlusive myocardial infarction (OMI) vs. non-occlusive myocardial infarction (NOMI) paradigm aims to improve acute myocardial infarction (AMI) identification.
\r\n \r\n Objective:<\/strong> \r\n \r\nTo examine OMI prevalence among NSTEMIS in a Cape Town emergency centre in 2019 and evaluate cardiac troponin I (cTnI) levels, angiography rates, thrombolysis in myocardial infarction (TIMI) flow grades, and door-to- angiogram times.\r\n
\r\n\r\n Methods:<\/strong> \r\n \r\nA retrospective cross-sectional study of 31 NSTEMI patients using descriptive statistics, Chi-square tests, and Mann-Whitney U tests.\r\n
\r\n \r\n Results:<\/strong> \r\nOMI was identified in 83.9% (n = 26) of NSTEMIS. Significant cTnI levels (median 1450 ng\/L, p = 0.001) and a median door-to-angiogram time of 34 hours were observed. \r\n
\r\n \r\n \r\n Conclusion:<\/strong> \r\n \r\nThe high OMI prevalence underscores the need for revised diagnostic and management strategies. Further multi-centre research is needed to validate findings and evaluate whether early OMI identification improves outcomes.\r\n
\r\n \r\n\r\n \r\n <\/div> \r\n <\/div> \r\n \r\n \r\n
\r\n \r\n Keywords:<\/strong> \r\n \r\n occlusive myocardial infarction, myocardial infarction, non-ST-elevation myocardial infarction, acute coronary syndrome<\/strong> \r\n \r\n <\/div> \r\n \r\n
\r\n \r\n Submitted:<\/strong> January 2, 2025; \r\n Accepted:<\/strong> May 12, 2025; \r\n Published:<\/strong> October 27, 2025
\r\n Cardiovasc J Afr 2025; 36<\/b>: 515-522<\/em>\r\n
Volume 36, Issue 4<\/strong>
\r\n <\/div> \r\n \r\n
\r\n DOI Citation Reference: dx.doi.org\/10.5830\/CVJA-2025-074 \r\n <\/div> \r\n \r\n
\r\n\r\nDivision of Emergency Medicine, University of Cape Town, South Africa\r\n<\/strong>
\r\nElmari Schoeman\r\nIbrahim D\u2019Andrea\r\nWillem Stassen\r\n\r\n

\r\n \r\n\r\n [soshsc hide=\"logged\"]\r\n You need to be logged in to view and download<\/a> the full text PDF version. Register for a free account?<\/a><\/strong>

[\/soshsc]\r\n \r\n \r\n \r\n <\/div>\r\n \r\n<\/div>","protected":false},"excerpt":{"rendered":"

ST-elevation myocardial infarction (STEMI) is associated with acute coronary occlusion, while non-ST- elevation myocardial infarction (NSTEMI) is often associated with partial occlusion. However, 25.5% of NSTEMIS involve complete occlusion, impacting mortality and major adverse cardiovascular events (MACE). The occlusive myocardial infarction (OMI) vs. non-occlusive myocardial infarction (NOMI) paradigm aims to improve acute myocardial infarction (AMI) identification.<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[44,108],"tags":[],"class_list":["post-5258","post","type-post","status-publish","format-standard","hentry","category-cardiovascular-topics","category-volume-36-issue-4"],"yoast_head":"\nPrevalence of occlusive myocardial infarction in patients diagnosed with non-ST-elevation myocardial infarction at a single private facility in Cape Town, South Africa - Cardiovascular Journal of Africa<\/title>\n<meta name=\"description\" content=\"ST-elevation myocardial infarction (STEMI) is associated with acute coronary occlusion, while non-ST- elevation myocardial infarction (NSTEMI) is often associated with partial occlusion. 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