{"id":5272,"date":"2025-11-19T11:59:59","date_gmt":"2025-11-19T09:59:59","guid":{"rendered":"https:\/\/cvja.co.za\/journal\/?p=5272"},"modified":"2026-05-05T14:26:46","modified_gmt":"2026-05-05T12:26:46","slug":"cvja-2025-060","status":"publish","type":"post","link":"https:\/\/cvja.co.za\/journal\/cvja-2025-060\/","title":{"rendered":"Hypertension treatment practices and outcomes at health community centres in urban Soweto, South Africa"},"content":{"rendered":"
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\r\n \r\n \r\nKudakwashe Nyamupangedengu, David Twesigomwe, Andrew K. May, Neil Martinson, Ziyaad Waja, Raadhiya Osman, Collen Masimirembwa, Mich\u00e8le Ramsay\r\n<\/div> \r\n<\/div> \r\n
\r\n Copyright:<\/strong> Clinics Cardive Publishing (Pty) Ltd. publisher\r\n of Cardiovascular Journal of Africa.<\/div>\r\n
<\/div> \r\n
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\r\n Abstract \r\n <\/div> \r\n \r\n
\r\n \r\n \r\n \r\n \r\nIn this study, we explored hypertension (HT) management in urban Soweto, South Africa, involving 364 participants from primary healthcare clinics. At baseline, 40% of participants were prescribed one drug, and 53% were given two drugs. Thiazide diuretics and calcium channel blockers were most prescribed at baseline. Blood pressure (BP) control at the first follow-up was achieved by 50% of those on single- drug therapy and 52% of those on two-drug therapy. Men showed higher rates of uncontrolled BP (60%) compared to women (42%). Significant factors influencing BP reduction included age, sex, waist circumference, and treatment clinic. In this study, single and combination therapies yielded similar outcomes in BP control. The study suggests that HT treatment approaches varied between clinics, potentially due to comorbidities and continuity of care challenges. Further research is needed to identify best practices across different South African settings, considering drug availability and cost.\r\n
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\r\n \r\n Keywords:<\/strong> \r\n \r\n hypertension (HT), blood pressure (BP) control, urban Soweto, South Africa, primary healthcare clinics, single- drug therapy, combination therapy, thiazide diuretic, calcium channel blocker<\/strong> \r\n \r\n <\/div> \r\n \r\n
\r\n \r\n Submitted:<\/strong> August 26, 2024; \r\n Accepted:<\/strong> December 10, 2024; \r\n Published:<\/strong> November 19, 2025
\r\n Cardiovasc J Afr 2025; 36<\/b>: 427-437<\/em>\r\n
Volume 36, Issue 4<\/strong>
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\r\n DOI Citation Reference: dx.doi.org\/10.5830\/CVJA-2025-060 \r\n <\/div> \r\n \r\n
\r\n\r\nSydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa \r\n\r\n<\/strong>
\r\nKudakwashe Nyamupangedengu
\r\nMich\u00e8le Ramsay
\r\nDavid Twesigomwe\r\n\r\n

\r\n\r\nDivision of Human Genetics, National Health Laboratory Services and School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa\r\n\r\n<\/strong>
\r\nKudakwashe Nyamupangedengu\r\n\r\n

\r\n\r\nDepartment of Biomolecular Sciences, School of Life Science, Pharmacy, and Chemistry, Kingston University London, London, United Kingdom\r\n\r\n<\/strong>
\r\nAndrew K. May\r\n\r\n

\r\n\r\nPerinatal HIV Research Unit (PHRU), University of the Witwatersrand, Johannesburg, South Africa\r\n\r\n<\/strong>
\r\nRaadhiya Osman\r\nZiyaad Waja\r\nNeil Martinson\r\n

\r\n\r\nAfrican Institute of Biomedical Science & Technology, Wilkins Hospital, Harare, Zimbabwe\r\n\r\n<\/strong>
\r\nCollen Masimirembwa\r\n\r\n

\r\n \r\n\r\n [soshsc hide=\"logged\"]\r\n You need to be logged in to view and download<\/a> the full text PDF version. Register for a free account?<\/a><\/strong>

[\/soshsc]\r\n \r\n \r\n \r\n <\/div>\r\n \r\n<\/div>","protected":false},"excerpt":{"rendered":"

In this study, we explored hypertension (HT) management in urban Soweto, South Africa, involving 364 participants from primary healthcare clinics. 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