{"id":5383,"date":"2026-02-20T11:09:37","date_gmt":"2026-02-20T09:09:37","guid":{"rendered":"https:\/\/cvja.co.za\/journal\/?p=5383"},"modified":"2026-02-20T11:17:47","modified_gmt":"2026-02-20T09:17:47","slug":"cvja-2025-098","status":"publish","type":"post","link":"https:\/\/cvja.co.za\/journal\/cvja-2025-098\/","title":{"rendered":"Correlates of serum thiamine levels among acute decompensated heart failure patients"},"content":{"rendered":"
\r\n
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\r\n \r\n \r\nBusayo O. Oguntola, Rasaq A. Adebayo, Suraj A. Ogunyemi, Tewogbade A. Adedeji, Stephen O. Oguntola, Olumide A. Akinyele, Obafemi S. Adesanya, Anthony O. Akintomide\r\n<\/div> \r\n<\/div> \r\n
\r\n Copyright:<\/strong> Clinics Cardive Publishing (Pty) Ltd. publisher\r\n of Cardiovascular Journal of Africa.<\/div>\r\n
<\/div> \r\n
\r\n
\r\n Abstract \r\n <\/div> \r\n \r\n
\r\n \r\n \r\n \r\n \r\n\r\n Background:<\/strong> \r\n \r\nAcute decompensated heart failure (ADHF) contributes adversely to health-related outcomes. Anorexia, early satiety, high metabolic rates, malnutrition, advanced age, and diuretic use characterise ADHF. This necessitated evaluating the correlates of low serum thiamine levels among ADHF patients in our facility.
\r\n\r\n Methods:<\/strong> \r\n \r\nThis was a case-control study. One hundred and ten participants (55 AHF patients with 55 age and sex-matched healthy controls) were recruited consecutively. All participants had a physical examination, resting 12-lead ECG, 2D transthoracic echocardiography and baseline laboratory investigations and serum thiamine. Data analysis was done using STATA 13.1.\r\n
\r\n \r\n Results:<\/strong> \r\nThe mean age of the study population was 45 (\u00b1 13.7) years. The mean serum thiamine levels among the ADHF and controls were 116.7 \u00b1 31.6 nmol\/L and 124.4 \u00b1 29.8 nmol\/L, respectively. Male gender, resting ECG QRS duration, and serum NT-proBNP independently predicted serum thiamine levels.\r\n
\r\n \r\n \r\n Conclusion:<\/strong> \r\n \r\nIn this study, male gender, NT-proBNP and QRS duration independently predicted serum thiamine levels.\r\n
\r\n \r\n\r\n \r\n <\/div> \r\n <\/div> \r\n \r\n \r\n
\r\n \r\n Keywords:<\/strong> \r\n \r\n serum thiamine, acute decompensated heart failure, acute heart failure<\/strong> \r\n \r\n <\/div> \r\n \r\n
\r\n \r\n Submitted:<\/strong> January 4, 2025; \r\n Accepted:<\/strong> September 18, 2025; \r\n Published:<\/strong> February 20, 2026
\r\n Cardiovasc J Afr 2025; 37<\/b>: 10-16<\/em>\r\n
Volume 37, Issue 1<\/strong>
\r\n <\/div> \r\n \r\n
\r\n DOI Citation Reference: dx.doi.org\/10.5830\/CVJA-2025-098 \r\n <\/div> \r\n \r\n
\r\n\r\n\r\nDepartment of Internal Medicine, ABUAD Multisystem Hospital, Afe Babalola University, Ado-Ekiti, 360101, Nigeria.\r\n<\/strong>
\r\nBusayo O. Oguntola
\r\nStephen O. Oguntola\r\n\r\n

\r\n\r\nCardiology Unit, Department of Internal Medicine, Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Osun State.\r\n<\/strong>
\r\nRasaq A. Adebayo
\r\nSuraj A. Ogunyemi
\r\nOlumide A. Akinyele
\r\nAnthony O. Akintomide\r\n\r\n

\r\n\r\nDepartment of Chemical Pathology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife.\r\n<\/strong>
\r\nTewogbade A. Adedeji\r\n\r\n

\r\n\r\nAcute and General Medicine, West Cumberland Hospital, Homewood Road, Whitehaven, CA28 8JG, United Kingdom\r\n<\/strong>
\r\nObafemi S. Adesanya\r\n\r\n

\r\n \r\n\r\n [soshsc hide=\"logged\"]\r\n You need to be logged in to view and download<\/a> the full text PDF version. Register for a free account?<\/a><\/strong>

[\/soshsc]\r\n \r\n \r\n \r\n <\/div>\r\n \r\n<\/div>","protected":false},"excerpt":{"rendered":"

Acute decompensated heart failure (ADHF) contributes adversely to health-related outcomes. Anorexia, early satiety, high metabolic rates, malnutrition, advanced age, and diuretic use characterise ADHF. This necessitated evaluating the correlates of low serum thiamine levels among ADHF patients in our facility.<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[44,109],"tags":[],"class_list":["post-5383","post","type-post","status-publish","format-standard","hentry","category-cardiovascular-topics","category-volume-37-issue-1"],"yoast_head":"\nCorrelates of serum thiamine levels among acute decompensated heart failure patients - Cardiovascular Journal of Africa<\/title>\n<meta name=\"description\" content=\"Acute decompensated heart failure (ADHF) contributes adversely to health-related outcomes. 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