{"id":5412,"date":"2026-03-06T13:42:50","date_gmt":"2026-03-06T11:42:50","guid":{"rendered":"https:\/\/cvja.co.za\/journal\/?p=5412"},"modified":"2026-03-06T13:42:50","modified_gmt":"2026-03-06T11:42:50","slug":"cvja-2025-095","status":"publish","type":"post","link":"https:\/\/cvja.co.za\/journal\/cvja-2025-095\/","title":{"rendered":"Analysis of the value of stress echocardiography in latent left ventricular outflow tract obstruction in non-hypertrophic cardiomyopathy"},"content":{"rendered":"
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\r\n \r\n \r\nYing Zhou, Luping Long, Yan Jiang, Jun Xu, Bin Shen\r\n<\/div> \r\n<\/div> \r\n
\r\n Copyright:<\/strong> Clinics Cardive Publishing (Pty) Ltd. publisher\r\n of Cardiovascular Journal of Africa.<\/div>\r\n
<\/div> \r\n
\r\n
\r\n Abstract \r\n <\/div> \r\n \r\n
\r\n \r\n \r\n \r\n \r\n\r\nThe accurate diagnosis of latent left ventricular outflow tract obstruction (LVOTO) in non-hypertrophic cardiomyopathy (NHCM) is crucial for treatment selection. This study evaluates the diagnostic value of stress echocardiography (SE) in detecting LVOTO in NHCM patients. We retrospectively analysed SE data from 33 NHCM patients with latent LVOTO and 35 NHCM patients without LVOTO, collected between January 2021 and July 2025. Key echocardiographic findings showed significantly greater posterior mitral leaflet length (1.97 \u00b1 0.21 cm vs 1.38 \u00b1 0.43 cm), anterior mitral leaflet length (2.68 \u00b1 0.70 cm vs 2.16 \u00b1 0.60 cm), and mitral valve coaptation length (1.04 \u00b1 0.17 cm vs 0.51 \u00b1 0.22 cm) in the latent LVOTO group. The peak systolic flow velocity (4.75 \u00b1 1.35 m\/s vs 1.92 \u00b1 0.75 m\/s) and pressure gradient (91.08 \u00b1 10.36 mmHg vs 16.36 \u00b1 5.68 mmHg) were significantly higher in the latent LVOTO group. SE is an effective tool for diagnosing latent LVOTO in NHCM, enhancing clinical decision-making.\r\n
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\r\n \r\n Keywords:<\/strong> \r\n \r\n Echocardiography, Non-hypertrophic cardiomyopathy, Latent left ventricular outflow tract obstruction, Exercise stress, Pharmacological stress<\/strong> \r\n \r\n <\/div> \r\n \r\n
\r\n \r\n Submitted:<\/strong> September 13, 2024; \r\n Accepted:<\/strong> October 20, 2025; \r\n Published:<\/strong> March 6, 2026
\r\n Cardiovasc J Afr 2025; 37<\/b>: 62-68<\/em>\r\n
Volume 37, Issue 1<\/strong>
\r\n <\/div> \r\n \r\n
\r\n DOI Citation Reference: dx.doi.org\/10.5830\/CVJA-2025-095 \r\n <\/div> \r\n \r\n
\r\n\r\n\r\nDepartment of Ultrasound, Chongqing Kangxin Hospital, Chongqing, 400025, China\r\n<\/strong>
\r\nYing Zhou
\r\nLuping Long
\r\nYan Jiang
\r\nJun Xu
\r\nBin Shen\r\n\r\n

\r\n \r\n\r\n [soshsc hide=\"logged\"]\r\n You need to be logged in to view and download<\/a> the full text PDF version. Register for a free account?<\/a><\/strong>

[\/soshsc]\r\n \r\n \r\n \r\n <\/div>\r\n \r\n<\/div>","protected":false},"excerpt":{"rendered":"

The accurate diagnosis of latent left ventricular outflow tract obstruction (LVOTO) in non-hypertrophic cardiomyopathy (NHCM) is crucial for treatment selection. 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