{"id":5608,"date":"2026-06-12T09:07:51","date_gmt":"2026-06-12T07:07:51","guid":{"rendered":"https:\/\/cvja.co.za\/journal\/?p=5608"},"modified":"2026-06-12T09:09:03","modified_gmt":"2026-06-12T07:09:03","slug":"cvja-2026-001","status":"publish","type":"post","link":"https:\/\/cvja.co.za\/journal\/cvja-2026-001\/","title":{"rendered":"The relationship between symptomatic lower extremity peripheral artery disease with carotid artery stenosis and ischemic stroke"},"content":{"rendered":"
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\r\n \r\n \r\nHasan H\u00fcseyin K\u0131r, Mehmet I\u015f\u0131k, \u00d6mer Tanyeli, Mukaddes R\u00fcveydao\u011flu Ceran, Ali Vasfi A\u011flarc\u0131, Muhammet Talha Ceran, Hasan H\u00fcseyin Kozak\r\n<\/div> \r\n<\/div> \r\n
\r\n Copyright:<\/strong> Clinics Cardive Publishing (Pty) Ltd. publisher\r\n of Cardiovascular Journal of Africa.<\/div>\r\n
<\/div> \r\n
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\r\n Abstract \r\n <\/div> \r\n \r\n
\r\n \r\n \r\n \r\n \r\n\r\n Objective:<\/strong> \r\n \r\nThe aim of this study was to investigate the prevalence of carotid artery stenosis (CAS) in peripheral artery disease (PAD) patients requiring surgical or interventional procedures, to examine the clinical relationship between CAS and PAD, and to determine the characteristics of ischemic stroke developing within a one-year postoperative period.\r\n
\r\n\r\n Methods:<\/strong> \r\n \r\nBetween August 2020 and January 2024, Doppler ultrasonography was performed to image the carotid arteries in patients diagnosed with PAD who underwent interventional procedures or surgical operations (Fontaine classification stage 2B and above). A total of 108 patients who continued follow-up were prospectively monitored for cerebrovascular events for 1 year.\r\n
\r\n \r\n Results:<\/strong> \r\nA near-significant association was observed between claudication distance and history of stroke (p = 0.08). Another near-significant association was found between claudication distance and National Institutes of Health Stroke Scale (NIHS) scores in patients who had a stroke (p = 0.07). A positive correlation (p < 0.01) was found between a history of stroke with severe CAS and NIHSS scores.\r\n
\r\n \r\n \r\n Conclusions:<\/strong> \r\n \r\nIn our study, we found that the prevalence of CAS was higher in PAD patients compared to the general population, and that they had a significant risk of cerebrovascular events during follow-up. Our study supports other studies recommending routine carotid ultrasound in patients diagnosed with PAD. The use of simple clinical measures such as claudication distance in cerebrovascular risk assessment may be beneficial in developing early diagnosis and treatment strategies in clinical practice.\r\n
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\r\n \r\n Submitted:<\/strong> October 30, 2025; \r\n Accepted:<\/strong> December 17, 2025; \r\n Published:<\/strong> June 12, 2026
\r\n Cardiovasc J Afr 2025; 37<\/b>: 234-238<\/em>\r\n
Volume 37, Issue 2<\/strong>
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\r\n DOI Citation Reference: dx.doi.org\/10.5830\/CVJA-2026-001 \r\n <\/div> \r\n \r\n
\r\n\r\n\r\nNecmettin Erbakan University, Faculty of Medicine, Neurology Clinic, Konya, Turkey\r\n\r\n<\/strong>
\r\nHasan H\u00fcseyin K\u0131r
\r\nMukaddes R\u00fcveydao\u011flu Ceran
\r\nHasan H\u00fcseyin Kozak\r\n

\r\n\r\nNecmettin Erbakan University, Faculty of Medicine, Cardiovascular Surgery Clinic, Konya, Turkey\r\n\r\n<\/strong>
\r\nMehmet I\u015f\u0131k
\r\n\u00d6mer Tanyeli
\r\nMuhammet Talha Ceran\r\n

\r\n\r\nKastamonu University, Faculty of Medicine, Department of Biostatistics, Kastamonu, Turkey\r\n\r\n<\/strong>
\r\nAli Vasfi A\u011flarc\u0131\r\n\r\n

\r\n \r\n\r\n [soshsc hide=\"logged\"]\r\n You need to be logged in to view and download<\/a> the full text PDF version. Register for a free account?<\/a><\/strong>

[\/soshsc]\r\n \r\n \r\n \r\n <\/div>\r\n \r\n<\/div>","protected":false},"excerpt":{"rendered":"

The aim of this study was to investigate the prevalence of carotid artery stenosis (CAS) in peripheral artery disease (PAD) patients requiring surgical or interventional procedures, to examine the clinical relationship between CAS and PAD, and to determine the characteristics of ischemic stroke developing within a one-year postoperative period.<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[44,110],"tags":[],"class_list":["post-5608","post","type-post","status-publish","format-standard","hentry","category-cardiovascular-topics","category-volume-37-issue-2"],"yoast_head":"\nThe relationship between symptomatic lower extremity peripheral artery disease with carotid artery stenosis and ischemic stroke - 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