{"id":5711,"date":"2026-09-11T08:12:47","date_gmt":"2026-09-11T06:12:47","guid":{"rendered":"https:\/\/cvja.co.za\/journal\/?p=5711"},"modified":"2026-09-11T08:12:47","modified_gmt":"2026-09-11T06:12:47","slug":"cvja-2026-014","status":"publish","type":"post","link":"https:\/\/cvja.co.za\/journal\/cvja-2026-014\/","title":{"rendered":"Neurological and neurocognitive outcomes of routine deep hypothermic circulatory arrest with open distal anastomosis in ascending aortic and aortic root aneurysm surgery"},"content":{"rendered":"
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\r\n \r\n \r\nMehmet Inanc Yesilkaya, Anil Karaagac, Gulbun Asuman Yuksel, Tolga Can, Yusuf Kagan Pocan, Ozan Erturk, Burak Bozkurt, Mehmet Kaplan\r\n<\/div> \r\n<\/div> \r\n
\r\n Copyright:<\/strong> Clinics Cardive Publishing (Pty) Ltd. publisher\r\n of Cardiovascular Journal of Africa.<\/div>\r\n
<\/div> \r\n
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\r\n Abstract \r\n <\/div> \r\n \r\n
\r\n \r\n \r\n \r\n This study aimed to evaluate postoperative neurological and neurocognitive changes in patients undergoing ascending aortic and aortic root aneurysm surgery using the deep hypothermic circulatory arrest technique with open distal anastomosis performed without cerebral perfusion. Thirty-six patients (83.3% male, n = 30; 16.7% female, n = 6) were included. Demographic, operative, and postoperative data were recorded. Each patient underwent the Mini-Mental State Examination (MMSE), the Oktem Verbal Memory Processes Test (OVMPT), and the Wechsler Memory Scale-Visual Reproduction Test (WMS-VR) before and one week after surgery. Cerebral oxygen saturation levels were continuously monitored using near-infrared spectroscopy. Postoperative OVMPT scores showed significant improvement (p < 0.001). No significant change was observed in the WMS-VR, while MMSE scores showed a slight but significant postoperative decline (p < 0.001). No associations were found between neurocognitive outcomes and operative variables. These findings indicate that this procedure can be performed with acceptable early neurological outcomes. \r\n\r\n
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\r\n \r\n Keywords:<\/strong> \r\n \r\n ascending aorta, aneurysm, deep hypothermia, circulatory arrest, neurocognitive function<\/strong> \r\n \r\n <\/div> \r\n \r\n
\r\n \r\n Submitted:<\/strong> November 12, 2025; \r\n Accepted:<\/strong> February 25, 2026; \r\n Published:<\/strong> September 11, 2026
\r\n Cardiovasc J Afr 2025; 37<\/b>: 325-331<\/em>\r\n
Volume 37, Issue 3<\/strong>
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\r\n DOI Citation Reference: dx.doi.org\/10.5830\/CVJA-2026-014 \r\n <\/div> \r\n \r\n
\r\n\r\n\r\nDepartment of Cardiovascular Surgery, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey, 34674\r\n\r\n<\/strong>
\r\nMehmet Inanc Yesilkaya
\r\nAnil Karaagac
\r\nTolga Can
\r\nYusuf Kagan Pocan
\r\nOzan Erturk
\r\nBurak Bozkurt
\r\nMehmet Kaplan\r\n

\r\n\r\nDepartment of Neurology, Istanbul Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey, 34674\r\n\r\n<\/strong>
\r\nGulbun Asuman Yuksel\r\n

\r\n\r\n\r\n [soshsc hide=\"logged\"]\r\n \r\n You need to be logged in to view and download<\/a> the full text PDF version. Register for a free account?<\/a><\/strong>

[\/soshsc]\r\n \r\n \r\n \r\n <\/div>\r\n \r\n<\/div>","protected":false},"excerpt":{"rendered":"

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