AFRICA CARDIOVASCULAR JOURNAL OF AFRICA • PAFCIC 2021 Abstracts December 2021 28 Submission ID: 999 CLINICAL, ELECTRICAL AND ANGIOGRAPHIC CHARACTERISTICS OF YOUNG PATIENTS WITH ACUTE MYOCARDIAL INFARCTION Allouche Emna, Neji Syrine, Ghariani Anis, Aissa MS., Ben jemaa H., Béji M., Ouachtati W., Ben Abdessalem Mohamed Aymen, Ben Ahmed Habib, Bezdah Leila, UHC Charles Nicolle, Tunisia. UHC Farhat Hached, Tunisia Background: Myocardial infarction’s prevalence among the young adults is increasing day by day. The aim of our study was to assess the clinical, electrical and angiographic characteristics of young patients Submission ID: 1004 ENDOCORONARY STENT THROMBOSIS: IN-HOSPITAL MORTALITY AND ITS PREDICTORS Fadwa Omri, Mejdi Ben Messaoud, Skander Bouchnag, Ammar Dhouibi, Mahdi Boussaada, Nidhal Bouchahda, Marouen Mahjoub, Majed Hassine, Fethi Betbout, Habib Gamra Introduction: Stent thrombosis (ST) isa relatively infrequent event after percutaneous coronary intervention, though it remains one of the most feared complications given the associated morbidity and mortality. Materials and methods: It’s a monocentric, retrospective, descriptive and analytic study including 40 patients hospitalized for angiographically definite ST in the Cardiology « A » Department of Fattouma Bourguiba University Hospital, during the period between January 1st 2013 and November 30th 2019. Objectives: The objective of our study was to specify the incidence and the predictors of in-hospital mortality related to ST. Results: In-hospital mortality occured in 25% of cases. The incidence of in-hospital mortality was higher in the case of early ST (28.6%) compared to late and very late ST (21.0%), with no significant difference (p = 0.707). During the years of study, in-hospital mortality was fluctuated. This variation is statistically significant (p = 0.001). The independent predictors of this mortality were: cardiopulmonary arrest at admission (p = 0.015), femoral approach (p = 0.007), diseased coronary distality (p = 0.015), pre- (p = 0.014) and post-procedural (p <0.001) TIMI 0 flow, use of adrenalin (p <0.001) and intubation (p<0.001). Conclusion: ST is a rare complication of PCI in our current practice, but is associated with a heavy in-hospital mortality. A better understanding and management of ST in our context are necessary to improve its prognosis. MODERATED POSTER SESSION 2 Submission ID: 990 CONGENITAL STRUCTURAL HEART DISEASES ASSOCIATED WITH CORONARY ABNORMALITIES Houssem Thabet, Marwen Kacem, Rym Gribaa, Ayoub Meddeb, Mehdi Slim, Hela Kaddour, Saeb Ben Saad, Sameh Ben Farhat, Sami Ouannes, Imen Ben Ali, Aymen Hraiech, Elyes Neffati Cardiology department, Sahloul university hospital, Sousse, Tunisia BACKGROUND: The anomalies of the coronary arteries are very varied and rare; they can concern the birth, the course or the termination of the coronary arteries. These coronary abnormalities can be isolated or associated with structural congenital heart diseases (CHD). AIM: The aim of this work was to describe patients with CHD and coronary abnormalities, their clinical and evolutionary particularities. MATERIAL AND METHOD: Between 1998 and 2017, 10 patients with a coronary anomaly of birth or path associated with CHD were collected. Were retrospectively analyzed: the circumstances of discovery, the ECG, the chest X-ray, data from the TTE, the coronary angiography, as well as the longterm follow-up. RESULTS: 10 patients with a coronary anomaly of birth or path associated with CHD were collected. The mean age of discovery of coronary anomalies was 14 months (ranging from 1 day to 4 years). We noted a male predominance (8 boys). All the circumstances in which coronary anomalies were discovered were fortuitous during an angiogram performed for diagnostic or therapeutic purposes of the associated underlying heart disease. Conotronic heart diseases was the most common.Tetralogy of Fallot was the most common CHD (4 children), followed by VSD (in 3 children), complex heart disease in 2 children and simple TGV in one child. All the children had an aortic coronary connection defect of which 4 had an abnormal birth from the opposite sinus, 3 had a left coronary artery from the posterior non-coronary sinus, 2 children had an LAD which originated from the right coronary, and multiple ostium cases. 3 patients had an anomaly of the proximal coronary path of which 2 had an interaortico-pulmonary path and one child had a retro-aortic path. At TTE, LVEF was conserved in 9 cases. The diagnosis of birth defects and coronary artery disease were confirmed by angiography in all cases. A CCT has only been performed in one child. The mean duration of follow-up was 6 years. All CHD were treated. Coronary anomalies were respected, and we decided to monitor patients. Long-term follow-up showed that only one child had NYHA stage II dyspnea(the one who had a complex heart disease: single ventricle with malposed vessels and pulmonary stenosis).The other children were asymptomatic. CONCLUSION: Coronary birth anomalies are varied. In our work, the birth defect of the opposite sinus was the most observed.Conotronic heart disease was the most associated with coronary anomalies. with acute myocardial infarction and to describe the prevalence of in-hospital complications. Methods: From January 2014 to May 2017, we retrospectively studied data of patients with acute myocardial infarction younger than 45 years old in the department of cardiology of Charles Nicolle hospital of Tunis. Results: We enrolled 108 patients in the study. The prevalence of myocardial infarction in young patients was 8.5%. The mean age was 39.5 ± 5.5 years with a sex-ratio of 11. The most frequent cardiovascular risk factors were smoking (88%) and dyslipidaemia (51.9%). We reported 75 cases of ST segment elevation myocardial infarction. Primary angioplasty was performed in 41.3% of cases while lytic therapy was administered for the rest of the patients. It was successful in 75% of cases. Among 33 patients who presented with non-ST segment elevation myocardial infarction, percutaneous coronary angioplasty was performed in 60.6% of patients while 15.2% have undergone coronary artery bypass surgery and 24.2% received medical treatment only. In-hospital complications occurred in 39.8% of cases. In-hospital mortality was 1.9 %. Conclusion: Acute myocardial infarction in the young represents a serious health problem. Primary preventive measures aimed at preventing our youth from adopting tobacco use and developing dyslipidemia should be implemented to delay and even to avoid the onset of coronary artery disease.
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