AFRICA CARDIOVASCULAR JOURNAL OF AFRICA • PAFCIC 2021 Abstracts December 2021 34 9 (75%) patients were on sinus rhythm. 25% (n=4) had severe dyspnea (NYHA III). There was a significant improvement of RV4CSL after PTMC (-20±4vs-23.9±4, p=0.036). The decrease of RVFWSL did not reach the statistical significance (-24±5vs-26.4±7, p=0.1). Interestingly, ∆RVFWSL was significantly correlated to ∆SVI (p=0.03). ∆RVFWSL and ∆RV4CSL did not correlate with ∆6MWD (p=0.6 and p=0.7 respectively). Conclusions: RV4CSL strain significantly improves after PTMC. This variation RVFWSL significantly correlates with the variation of SVI. Submission ID: 1138 INCIDENCE AND CLINICAL CHARACTERISTICS OF PATIENTS PRESENTING WITH MYOCARDIAL INFARCTION WITH NONOBSTRUCTIVE CORONARY ARTERIES (MINOCA) Nesrine Amdouni, Walid Jomaa, Ikram Chamtouri, Wajih Abdallah, Khaldoun ben Hamda, Faouzi Maatouk Cardiology B department of Fattouma Bourguiba University Hospital, Tunisia Background: Myocardial infarction (MI) with non-obstructive coronary arteries (MINOCA) is a heterogeneous entity often overlooked in contemporary medicine. Aim: To assess incidence and characteristics of MINOCA in a large cohort of patients admitted for myocardial infarction. Methods: A total of 1734 consecutive patients were retrospectively enrolled in the STEMI registry of the cardiology B department of Fattouma Bourguiba university hospital between January 1997 and December 2017. MINOCA was defined as a non-obstructive coronary artery disease and a lack of previous coronary revascularization. Clinical profile and prognosis of all patients were assessed. Results: The proportion of MINOCA patients among all myocardial infarction was 2.7%. The MINOCA patients were younger (age 47 ± 14.9 vs. 60.7 ± 12.4 years), more often males (87.2% vs. 78.7%) with significantly lower rates of diabetes mellitus (19.1% vs 36.4%, p=0.015), hypertension (10.6% vs 30.6%, p=0.003) , kidney disease (2.1% vs 7.8%, p=0.032) , peripheral artery disease (2.8% vs 8.3%, p=0.015) and previous MI (2.1% vs 11.1%, p=0.028) comparing to patients with obstructive coronary artery disease (CAD). History of smoking was more common in the MINOCA group. Typical chest pain at presentation was higher in MINOCA patients (98.6% vs 93,4%, p=0.046). MINOCA patients presented more frequently anterior ST- segment elevation. Allcause in-hospital and 5 years follow-up mortality rate was lower in the MINOCA patients ( 1.5% vs 9.6%, p<0.001 ; 7.6 vs 13.8%, p=0.036 respectively). Conclusion: MINOCA represents a challenging group of heterogeneous patients whose clinical characteristics contrast with classical cardiovascular risk factors. A search for etiology and eventual treatment provides a rich avenue for improving prognosis in patients with MINOCA. Submission ID: 1140 CLINICAL PRESENTATION, RISK FACTORS AND OUTECOMES IN WOMEN WITH ACUTE ST- ELEVATION MYOCARDIAL INFARCTION (STEMI) Nesrine Amdouni, Walid Jomaa, Ikram Chamtouri, Asma Ben Abdallah, Wajih Abdallah, Khaldoun ben Hamda, Faouzi Maatouk Cardiology B department of Fattouma Bourguiba University Hospital, Tunisia Background: Coronary artery disease is the leading cause of death in women. Women with ST-segment elevation myocardial infarctions continue to have worse outcomes compared with men despite advancements in therapies. Aim: To examine the clinical presentation, patient management , risk factors and inhospital outcomes of women with acute STEMI compared with men using data from a large STEMI registry from Fattouma Bourguiba University hospital. Methods: This retrospective study analyzed the data of 1734 patients admitted in Cardiology department of Fattouma Bourguiba University hospital between January 1997 and December 2017 diagnosed with STelevation myocardial infarction (STEMI). We recorded the baseline characteristics, comorbidities, treatment, complications, and mortality for all patients, and compared these data between female and male patients. Results: Of 1734 patients, there were 365 women (21%). The mean age in women was 64.8±11.8 years, which was significantly older than in men, 59.1±12.6 (p<.001). Women had more frequently diabetes mellitus, hypertension and anemia but were less current smokers comapred with men (all p<0.001). Fewer women had histories of previous coronary artery disease (p=0.012). Women had anterior STEMI in 55.3%. When primary percutaneous coronary intervention (PPCI) was performed, women had longer symptom-to-balloon time (6.4 ±9.2 vs.5.1 ±4.2 hours, p=0.045). When thrombolytic therapy was administrated, women had longer thrombolysis delay (4.7 ±3.2 vs. 3.9 ±3.3 hours, p=0.031). The mean duration of hospital stay was comparable between male and female (4.68 ± 3.47 vs. 4.65 ± 3.40 days, p=NS). The crude in-hospital mortality rate was significatively higher in women (13.4% vs. 8.3%, p=0.003). Conclusion: Mortality is higher in women with STEMI and can be explained by their older age ,unfavourable risk profile and longer symptom-to-balloon time. Correction of gaps in quality of care should be attempted to reduce the high morbidity and mortality of STEMI in our women. MODERATED POSTER SESSION 2 Submission ID: 1145 EPIDEMIOLOGICAL PROFILE AND BIOLOGICAL FACTORS PREDICTING IN-HOSPITAL MORTALITY IN INFECTIVE ENDOCARDITIS Nesrine Amdouni, Ikram Chamtouri, Asma Ben Abdallah, Chahrazed Abbes, Jomaa Walid, Wajih Abdallah, Khaldoun Ben Hamda, Faouzi Maatouk CARDIOLOGY DEPARTMENT B FATTOUMA BOURGUIBA HOSPITAL, Tunisia Introduction: Infective endocarditis (IE) is associated with high mortality. Evaluating the mortality rate and predictors of fatal events is important to identify modifiable factors and improve prognosis. Objective: Define the epidemiological profile and identify the biological factors predicting in-hospital mortality in patients with IE.
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