AFRICA CARDIOVASCULAR JOURNAL OF AFRICA • PAFCIC 2021 Abstracts December 2021 48 Submission ID: 1179 PREDICTORS OF RESIDUAL SHUNT AFTER PERCUTANEOUS CLOSURE OF THE PATENT DUCTUS ARTERIOSUS IN LOWER WEIGHT INFANTS dardouri safa, gribaa rim, ayoub meddeb, slim mehdi, ouanes sami, ben ali imen, el hraiech aymen, naffeti ilyes Sahloul Hospital, Tunisia Introduction: Patent ductus arteriosus (PDA) is one of the most common congenital heart disease. Transcatheter closure of small to moderate sized PDAs is an established procedure. Several complications can arise during this procedure including the residual shunt. Aim: The objectif of this study was to determine the frequency, and the predictive factors of the occurrence of immediate angiographic, and distant echocardiographic residual shunt, during the percutaneous PDA closure procedure, in children of low weight less than 6 kg. Materials and methods: It was a mono-center retrospective study, which has included 33 patients in lower weight less than 6 kg, hospitalized in the cardiology department of Sahloul hospital for percutaneous closure of their PDA. This was during the period from September 2003 to June 2021. Results: The mean age of patients during cardiac catheterization was 10.6 ± 5.4 months. A clear female predominance was noted with a sex ratio of 2.6. All patients were full-term newborn. Success rate of our procedure was 90.9% with 30 devices that were well deployed, and three cases of failure (9.1%). The ADO was the most deployed device with a percentage of 45.5% for ADOI and 21.2% for ADOII. At the angiographic check-up at the end of the procedure and after release of the device, a residual shunt was noted in 14 patients among the 30 patients who had successfully closed, ie in 46.7% of cases. It was in all cases insignificant. On echocardiographic check-up done systematically before the patient was discharged from the hospital, the residual shunt was still present in 7 of the 14 patients, and was always minimal. The multivariate analysis of the factors likely to increase the risk of residual shunt at the end of the procedure identified 4 parameters significantly correlated with this risk. An age of less than 6 months, a larger pulmonary diameter of the PDA, the presence of a pulmonary artery hypertension and a type C of PDA. Conclusion: Catheter-based PDA closure is the procedure of choice for ductal closure. Residual shunt should not be a deterrent to use of this method. Submission ID: 1213 MANAGEMENT OF ACUTE CORONARY SYNDROME WITHOUT ST-SEGMENT ELEVATION IN WOMEN MARIEM DRISSA, ASMA BRAHIM, ESSIA MOUSLI, HASSAN ABU NADA, HABIBA DRISSA LA RABTA HOSPITAL, TUNISIA Introduction: Despite the persistent perception that CAD is a man’s disease, it is often the most common cause of death in women, responsible for 7 times more deaths than breast cancer. Submission ID: 1222 PROGNOSIS OF PATIENTS CONSULTING FOR ACUTE CORONARY SYNDROME: ST-ELEVATION MYOCARDIAL INFARCTION (STEMI) BY GENDER AHMED BOUHLEL, ROUA CHOUIHI, MEHDI SLIM, BALKISS KHALAF, RIM YOUSSEF, HAKER YAACOUBI, HOUDA BEN SALAH, LOTFI BOUKADIDA, ASMA ZORGATI, RIADH BOUKEF Emergency department Sahloul Sousse, Tunisia Introduction: Cardiovascular disease is the leading cause of death in women. This excess mortality raises questions about possible specificities affecting the pathophysiology, diagnosis and prognosis Objective: To study the impact of on the prognosis of STEMI in the emergency room. Materials and methods: All emergency patients diagnosed with STEMI are included. We divided the patients into two groups according to sex: group I: group of men and group II: group of women. All demographic, clinical and biological characteristics of the patients are noted. Statistical analyzes are performed using SPSS18. Results: A predominance of men is observed in our population: 80.6% of the population are male and 19.6% are women. The outcome at one month is significantly different between the two groups in our study (p = 0.024). Indeed, all of the men benefited from coronary angioplasty, and PAC (coronary aorto bypass). The reconsultation rate is observed more among women. The MACE effects and mortality are observed in the group of women with still significant differences (0.02, 0.01 respectively). Intra-hospital mortality is observed in women more than men. While no significant difference between groups in mortality one month after admission to the emergency department. Conclusion: Although female patients have a higher cardiovascular risk profile and a reconsultation rate higher, no gender-based prognostic difference was seen in the emergency. MODERATED POSTER SESSION 3 Methods: We led a retrospective, observational and monocentric study including 200 patients (130men and 70 women) admitted for NSTE -ACS to our the cardiology department the university hospital la Rabta between January 2016 and December 2020. All epidemiological, clinical, therapeutic and prognostic data were compared in a gender perspective. Results: It was observed that women were more often hypertensive, sedentary, obese and with less smoking rates than men. Presentation and symptoms of coronary artery disease in women are often atypical and misleading. Despite their higher ischemic risk (64% for women versus 37% for men with high risk criteria) (p=0,01), women seem to benefit less of invasive strategy. Coronary angiography when performed often shows nonobstructive coronary disease (16% in women versus 6% in men) and a coronary revascularization is less frequently proposed in women (67% versus 85%) (p = 0,001). Conclusion: In spite of its importance and major impact, CAD in women is under-diagnosed and often associated to higher risk criteria than men. Yet, women remain undertreated with less adequate therapeutic strategies.
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