CARDIOVASCULAR JOURNAL OF AFRICA • PAFCIC 2021 Abstracts December 2021 51 AFRICA MODERATED POSTER SESSION 4 circumflex ostia dissection; hopefully treated with stenting. To cap it all, we realized that the LAD stent was also missing. Having a careful second look to the material retrieved previously, we discovered the LAD stent attached to the diagonal’s. A second attempt to stent the LAD led to a small dissection of the LM ostia. We decided to stop the procedure at this point as the patient was stabilized. Submission ID: 1007 STUDY OF RIGHT VENTRICULAR REMODELING AFTER PERCUTANEOUS MITRAL VALVE CLIPPING IN PATIENTS WITH SEVERE FUNCTIONAL MITRAL REGURGITATION Osama Rifaie, Reda Abulatta, Hesham Naem, Osama Alamoodi, Khaled Alkhashab, Tamer Ragab, Ibrahim nosseir Ainshams university, Egypt Background: Percutaneousmitral valve clipping (PMVC) is being used successfully in the management of severe functional mitral regurgitation (MR) in patients with high surgical risk. However, the impact of (PMVC) on right ventricular volumes and functions is not clear. Aim: The aim of the present study was to assess the impact of (PMVC) (in both short and long terms) on right ventricular (RV) volumes and functions using trans-thoracic echocardiography. Methods: The study population included 37 patients with severe (MR), and congestive heart failure who were at high surgical risk. The mean age was 61±14 years, 9 (24.3%) were males. (PMVC) was successfully done for all patients. All had clinical and echocardiographic follow up at 6 and 12-months post (PMVC). Results: MR showed significant improvement after (PMVC). MR was less than grade II in 29(78%) of patients at 6months and persisted at 12months (P = 0.008). Similarly, tricuspid regurgitation (TR) showed marked improvement. Severe (TR) was seen in 29 patients (78%) before), but was seen only in 7 patients (18.9%) after (PMVC) (P=0.004). Left ventricular ejection fraction (LVEF) improved from 32.63±13.35% at base line to 36.31±13.28 % and 34%at 6 months (P=0.003) This was maintained at 12 months (35.38±91%) .RV end diastolic volume (RVDV) decreased from 58±20.8 ml to 50.9±20.7ml and 52.9±31.9ml at 6 months and one year after (PMVC) respectively (P=0.001). RV end systolic volume (RVSV) decreased from 39.9±16.9ml to 32.4±20.4ml and 32.4±20.4ml at 6 months and one year respectively (P=0.004).RV ejection fraction(RVEF) increased from 34.1±9.9% to 42.3±12.8% at 6 months((P=0.001)and 45±18.3% at one year respectively. Tricuspid annulus plane systolic excursion(TAPSE) increased from 1.7±0.57cm to 2.0±0.7cm and 1.9±0.6cm at 6 months and one year respectively. (P=0.001). RV longitudinal systolic function by tissue Doppler imaging (TDI) increased from 10.5±2.3cm/s to13.9±3cm/s and 12.2±2.cm/s at 6months and one year respectively. Peak systolic pulmonary artery pressure (PASP). Dropped from 50.4±13.9mmHg to 42.7±13.6mmHg and 42.3±13.3 mmHg at 6 months and one year respectively. Conclusion: (PMVC) induced a significant reverse remodeling of RV by decreasing both (RVDV) and (RVSV). Moreover, it improved (TDI) as well as (RVEF), probably due to decrease in MR and (PSAP). This was maintained up to one year. Submission ID: 1082 SEX DIFFERENCES IN CLINICAL AND ANGIOGRAPHIC CHARACTERISTICS IN ACUTE CORONARY SYNDROME PATIENTS IN DAKAR NDAO Serigne Cheikh Tidiane, KA Mame Madjiguène, MBOUP Waly Niang, DIA Khadidiatou, MINGOU Joseph Salvador, FALL Pape Diadie, MBOUP Mouhamadou Chérif HOPITAL PRINCIPAL DAKAR, SENEGAL Background Coronary artery disease (CAD) is in relentless progression, along with the adoption of western lifestyle in sub-Saharan Africa. In Senegal, the prevalence of acute coronary syndrome (ACS) rose from 5% to 12% in Dakar during the last 20 years. That increase was observed in both women and men, and according to current data, the former pay the heaviest price in terms of mortality compared to men. In this study, we aim to retrospectively assess the clinical characteristics and angiographic profile of ACS in women compared to men in a tertiary care center in Dakar. Methods In this study were retrospectively analyzed and compared data between men and women among 133 patients who underwent coronary angiogram for ACS in 2 tertiary centers from February of 2019 to January 2020. Results A total of 133 patients were included in our study with 97 men (72.9%). The mean age was 58 ± 13.6 years, women were older than men (61.4 ±14.3 years vs 56.6 ±13.5 years (p=0.07). Hypertension, sedentary lifestyle and obesity were significantly more frequent in women (69.4%, 52.7% and 19.4%) when compared to men (38.8%, 25.7% and 6.19%) respectively, (p=0.001; 0.002 and 0.03). Smoking was in contrast less frequent in women (2.8%) versus 44.3% in men, (p<0.001. The mean time from diagnosis to coronary angiography was not statistically different regardless of the presentation mode. On coronary angiogram, single vessel disease was most common (36.1% of men vs 33.3% of women) followed by triple vessel disease (24.7% vs 19.4% respectively). The left anterior descending artery was the most commonly affected vessel (84.4% of men vs. 61.1% of women) in both sexes followed by the left circumflex artery. The left main stem was diseased similarly in both genders (around 8%). The majority of patients had low SYNTAX score but more often women than men (97.2% vs 92.78%, p=0.04). Among all the patients, 65 (48.9%) underwent PCI with no statistical difference between men and women. Conclusion In our study, women with ACS were older, had more cardiovascular risk factors but less angiographic extent of disease than men.
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