AFRICA CARDIOVASCULAR JOURNAL OF AFRICA • PAFCIC 2021 Abstracts December 2021 60 Submission ID: 1147 STENT THROMBOSIS AND TYPES OF CORONARY STENTS Fares Azaeiz, Ahmed Mlik, Rym Hentati, Rym Ben Romdhane, Sofien Zayid, Kaouthar Bachraoui, Rami Tlili, Youssef Ben Ameur University hospital Mongi Slim, Tunisia Background: Stent thrombosis is a serious complication with an increased mortality rate of 40% and major sequelae of MI in approximately 80% of survivors who remain at risk for frequent recurrence. The objective of our study is to analyze stent thrombosis and to identify the types of coronary stents favoring its occurrence according to local expertise. Methods: This was a single-center retrospective study conducted at the cardiology department of Mongi Slim University Hospital La Marsa over a seven-year period from January 2013 to December 2019. we recruited 50 patients who were victims of stent thrombosis and an equivalent number of patients hospitalized in the same department and who did not develop a stent thrombosis during the first 3 years after the implantation of an endocoronary prosthesis. Our work includes a comparative section of case-control. Results: Regarding the type of stents used in case group, 35 bare metal stents (57,4%) were implanted, whereas 19 second-generation drug eluting stents (31,2%), 5 biodegradable-polymer drug eluting stents (8,3%), only one first-generation active drug eluting stent (1,6%) and just one polymer-free drug eluting stent were implanted. Furthermore, 27 bare metal stents (38,2%) were implanted in the control group, 19 second-generation drug eluting stents (49,1%), 7 biodegradable-polymer drug eluting stents (12,7%), and no firstgeneration active drug eluting stent or polymer-free drug eluting stent were implanted. We observed a predominant use of the polymer “Everolimus” in both groups, with an incidence of 65% in the case group and 69% in the control group. Bare metal stents were clearly predominant in cases group that reached a statistically significant threshold with univariate analysis (p=0.04) and thus correlated with the occurrence of stent thrombosis There was also a preponderance of second-generation drug eluting stents in control groupe. Although close (P=0.08), the threshold of significance is not reached with the univariate study. Conclusion: we insist on the need to generalize the use of drug-eluting-stents in the treatment of coronary diseases in order to remedy this deadly pathology. Submission ID: 1149 THE RISE OF TRANSRADIAL ARTERY ACCESS FOR PERCUTANEOUS CORONARY INTERVENTION Fekih Romdhane Ahmed, Ghariani Anis, Ben Abdessalem Mohamed Aymen, Ben Ameur Zied, Ammar Fares, Saoudi Wassim, Mahdhaoui Abdallah, Jeridi Gouider UHC Farhat Hached, Tunisia Introduction Percutaneous coronary intervention (PCI) is associated with both ischaemic and bleeding complications. Transradial access (TRA) route has been proven to reduce bleeding risk. It has become recently the standard approach. Our aim was to investigate the trend in adoption of transradial access at our institution. Materials and Methods It was a retrospective study conducted in the cardiology department of Farhat Hached university hospital centre. From February 2014 to May 2021, patients who underwent a catheterization procedure were enrolled. The population was divided in two groups according MODERATED POSTER SESSION 4 to the admission period: first group from February 2014 to February 2015 and second group: from January 2020 to May 2021. In each group, initial coronary access route was evaluated. Results A total of 1440 patients underwent a coronary catheterization procedure. The first group consisted of 848 patients and the second group consisted of 592 patients. Baseline characteristics were similar in both groups. Transfemoral coronary access (TFA) was used in 52.9% in the first group against 1.7% in the second group (p<0.001). TRA was used in 46.8% in the first group against 98.3% in the second group (p<0.001). The percentage of success of the initial access route in 2014-2015 was 90% vs 93.8% in 2020-2021 (p value not significant). Conclusion Trans radial artery access for coronary catheterization at our institution steadily increased to over 98% of cases in a period of six years, representing the evolution of a major trend in interventional cardiology. Submission ID: 1160 TRANSCATHETER AORTIC VALVE REPLACEMENT FOR DEGENERATIVE BIOPROSTHETIC SURGICAL VALVESINTERVENTION Mariem Drissa, Essia Chahnez Mousli, Cyrine Aouiji La Rabta, Tunisia Background: Transcatheter aortic valve-in-valve implantation is an emerging therapeutic alternative for patientswith a failed surgical bioprosthesis and may obviate the need for reoperation especially in this type of population with high operative risk. We evaluated the clinical results of this technique on a patient case with degenerative bioprosthetic stenosis treated with transcatheter valve-in-valve (ViV) implantation. Case report: A 70-year-old woman underwent isolated aortic valve replacement (AVR) in 1995 for nonrheumatic aortic stenosis with a bioprosthesis. During 2013 she became increasingly dyspneic and was found to have severe aortic stenosis (AS) with moderate aortic regurgitation (AR). Her biologist test showed severe thrombocytemia, and given her resultant high operative risk score (logistic EuroSCORE 19%), she was referred for TAVI. A post-procedure echocardiogram the next day showed normal functioning of the valve, with a peak flow velocity of 2.7 m/s across it, a residual mean gradient of 19.5 mmhg and trivial aortic regurgitation. At one year of follow up, the patient was asymptomatic (stage I of the NYHA) with a maintained haemodynamic profile of the valve. Conclusion: We have confirmed the feasibility of TAVI in degenerative bioprostheses which gives results similar to TAVI on native valve. Long-term follow up of these patients is required to demonstrate ongoing benefits and limitations of this technique. Submission ID: 1170 THE PHARMACOLOGIC MANAGEMENT OF HEART FAILURE WITH REDUCED EJECTION FRACTION IN A TUNISIAN DEPARTMENT Drissa Mariem, Essia chahnez Mousli, Cyrine Aouji La Rabta, Tunisia Background: Chronic congestive heart failure is a common condition that, if untreated, markedly impairs the quality of life and is associated with
RkJQdWJsaXNoZXIy NDIzNzc=