AFRICA CARDIOVASCULAR JOURNAL OF AFRICA • SMC-PAFCIC Abstracts October 2022 26 Clinically - Heart failure was found in 26% of cases. - Stroke in 8% of cases, of which 6% were ischemic and 3.6% hemorrhagic. - Mycotic aneurysm found in 2.7% of cases Staphylococcus was the most common germ in 4.5% of cases, followed by streptococcus in 3.6%. At the ETT: - vegetations were most commonly found on the mitral valve in 35% of cases followed by the aortic in 23.6% and then the tricuspid in 6.3%. - Perivalvular abscesses were found in 10.9% followed by cord rupture in 9% and fistula in 6.3%. - Disinsertion of the prosthesis was found in 2.7% of cases, resulting in 1.8% of stenotic prostheses and 0.9% of leaking prostheses. Valve replacement was performed in 18% of our patients, i.e. 82% were treated medically alone and death was found in 16.3% of our patients. Conclusion: Our work has enabled us to observe that IE continues to affect a young population with rheumatic valve disease and congenital pathology, but also haemodialysis catheter users, although staphylococcus and streptococcus are co-predominant. Submission ID: 1448 TYPE 2 DIABETICS PRESUMED TO BE NORMOTENSIVE: MASKED HYPERTENSION, URINARY ALBUMIN EXCRETION RATE AND ECHOCARDIOGRAPHIC SCREENING SARA ABOURADI, HANANE CHOUKRANI, ANASS MAAROUFI, KHAWLA CHAWKI, GHALI BENOUNA, RACHIDA HABBAL MOROCCO Introduction: Hypertension is a major risk factor for the development and progression of chronic complications of type 2 diabetes . Masked hypertension has been reported to affect 2–26% of the population. Objective: To analyze the impact of masked hypertension in type 2 diabetic patients with regard to microvascular complications (including microalbuminuria) and echocardiographic parameters. Methods: We conducted a cross-sectional study on 130 normotensive and type 2 diabetic patients. Microalbuminuria assay, echocardiography and ambulatory blood pressure monitoring (ABPM) were performed. The inclusion criteria were a diagnosis of type 2 diabetes (> 10 years no previous episode of ketoacidosis or documented ketonuria, and assessed blood pressure <140/90 mmHg on at least two occasions. Patients with creatinine >15 g/dl, other renal disease, cardiac arrhythmia, or orthostatic hypotension were excluded. χ2 tests were used to compare clinical and laboratory data. Results: The main age was: 46+/- 12 years old , Sex ratio=1.2, 42% of patients were smoker 43% have masked hypertension and the mean HbA1c was 7.8 ± 2.0%. Nocturnal systolic blood pressure was higher in patients with masked hypertension than in the normotensive group (138.8 ± 5.5 vs 125 ± 8.4 mmHg, p = 0.002). Albiminuria was also increased in the masked hypertensive group (22 microg/min [2.5-1.5] vs 8.1 microg/min [1.0-0.22], p=0.001), as well as the thicknesses of the interventricular septum (1.1 +/- 0.10 vs 0.84 ± 0.9 cm, p = 0.015) and of the posterior wall (0.12 ± 0.8 vs 0.90 ± 0.10 cm, p=0.005). Conclusion: Type 2 diabetic patients with masked hypertension have higher prevalence of elevated micro and macroalbuminuria, and ventricular wall enlargement compared to normotensive patients. Evaluation of normotensive type 2 diabetic patients with 24-h ABPM, appears to be important in identifying this high-risk group. Submission ID: 1452 PROGNOSTIC VALUE OF DIASTOLIC DYSFUNCTION IN ACUTE MYOCARDIAL INFARCTION: A PROSPECTIVE STUDY SARA ABOURADI, ANASS MAAROUFI, HANANE CHOUKRANI, KHAWLA CHAWKI, SOUKAINA ZAGDAN, SALIM ARROUS, GHALI BENOUNA, RACHIDA HABBAL MOROCCO Introduction: During acute myocardial ischemia, left ventricular (LV) systolic dysfunction is sometimes associated with diastolic dysfunction that can sometimes precede the latter. Development of doppler echocardiography techniques has allowed the non-invasive measurement of LV diastolic filling, which correlates well with other measures of LV filling. Aim: The aim of our study was to demonstrate the prognostic value of diastolic dysfunction in the acute phase of acute coronary syndrome. Methodology: We prospectively included 123 patients admitted to the cardiology intensive care unit of Ibn Rochd Hospital in Casablanca between december 2021 and July 2022 , for acute coronary syndrome with or without persistent ST segment elevation. All patients had Doppler echocardiography within the first four days of admission. Results: The average age of our patients was 60.27 ± 12.35 years [28-85]. There was a slight male predominance (54.7% of the population). More than two-thirds of the patients were smokers (76.36%). Onequarter were hypertensive (23.63%), nearly half were diabetic (50.9%), and one quarter of our population had dyslipidemia. Coronary inheritance was found in 7.27% of our patients. Nine patients (16.36%) patients had high LVFP. Elevation of LVFP was a predictor of mortality (p = 0.01) and occurrence of major cardiovascular events at 6 months of follow-up (p = 0.001) Conclusion: The study of diastolic function and especially the evaluation of the LVFP at the acute phase of acute coronary syndrome allows to refine the stratification of patients admitted for an acute coronary syndrome and to identify a group of high risk patients to benefit from more intensive treatment. Submission ID: 1455 SUDDEN CARDIAC DEATH RISK STRATIFICATION OF THE EARLY REPOLARIZATION SYNDROME: AN UPDATED REVIEW OF THE LITERATURE MOHAMMED EL-AZRAK, CHARMAKE DARAR, MOHAMMED BOUTAYBI, NOHA EL OUAFI, ZAKARIA BAZID MOROCCO Background: Early repolarization syndrome (ERS), once thought to be innocuous, has now been shown to be responsible, in part, for ventricular arrythmias and sudden cardiac death occurrence, especially in young, male patients. The biggest challenge for the clinician is figuring out how to identify the patients who are most at risk for arrhythmias, so that they can adopt a preventive or secondary treatment approach, either of which is still poorly defined. This MODERATED POSTER SESSION
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