CARDIOVASCULAR JOURNAL OF AFRICA • SMC-PAFCIC Abstracts October 2022 27 AFRICA article is an updated review of the literature that has compiled the various clinical and electrical parameters that are significant in predicting rhythmic risk in individuals with ERS. Taken together, they allow to predict the malignancy of ER pattern with a certain reliability. Further research is however needed to develop concrete risk stratification algorithms and the therapeutic strategies taken in function of it. Clinical features 1. Men. 2. Young people. 3. A history of unexplained syncope, or a family history of SCD *. 4. Identified gene mutations. Electrocardiographic features 1. Inferolateral ER † location. 2. Horizontal or/and descending ST-segment. 3. Notching of the terminal part of the QRS complex. 4. J-point elevation of at least 2mm. 5. J waves of long duration, wide J angle. 6. low amplitude of T waves, and low T/R ratio. 7. Presence of Q waves and T waves inversion Association with other heart diseases 1. Association with coronary heart disease. 2. Association with another channelopathy. *SCD: Sudden cardiac death, † ER: Early repolarization Table 1 Summary of the various parameters associated with high arrhythmic risk in patients with early repolarization syndrome. Figure 1 ER aspects Figure 2 Duration and slope Submission ID: 1470 ASSESSMENT OF GLYCATED HEMOGLOBIN PREDICTIVITY IN THE SEVERITY OF CORONARY ARTERY DISEASE IN PATIENTS WITH OR WITHOUT DIABETES SLIM ABID, HICHEM DENGUIR, MOHAMED DERWICH, SAHAR KMIHA, RAHMA KALLEL, AHMED AL BATTRAOUI, HASAN AL ZAIN, MALAK TALLOUH TUNISIA Background: Diabetes mellitus (DM) has been identified for several years as a major risk factor for coronary artery disease (CAD) which is currently the leading cause of death worldwide. Prolonged hyperglycemia can weaken the artery walls and promotes the formation and the rupture of atherosclerotic plaques. Glycated hemoglobin (HbA1c), expressed as a percentage, is a function of blood sugar control over the previous two to three months. Generally, diabetes is controlled if the HbA1c level is less than or equal to 7%. Beyond that, the risk of developing long-term complications increases. Objective: Access the relationships between the HbA1c level in the blood and the severity of CAD in patients with or without diabetes undergoing coronary artery catheterization in an urban teaching hospital. Method: Across-sectional studywas conducted in theCardiologyDepartment of Gabes (Tunisia). Data were gathered from medical records of all patients who were recruited prior to cardiac catheterization for probable CAD between July (2021) and December (2021). The indications of cardiac catheterization were in accordance with international recommendations Results: A total of 208 patients were included in the study. Mean age was 63.1±12.04 years. Of the total 64.9% (135) were males, 32.7% (68) were diabetic, 53.4% (111) were hypertensives, 40.4% (84) were smokers and 31.3% (65) were dyslipidemia. First, we tested the normality of distribution of SYNTAX score and HbA1c revealed negative concluding to using Spearman test to study the correlation between these two variable. We found that CAD severity by SYNTAX score as well as number of vessels involved was weakly related to level of HbA1c using Spearman Correlation test. Increase in HbA1c level was moderately correlated with disease severity and higher SYNTAX score (p-value =0.006) with a correlation coefficient equal to 0.206. A moderate increase was noted in the mean number of diseased vessels as HbA1c level increases. Gender Smoking, hypertension and dyslipidemia did not show significant difference, however Age, was found to be an independent predictor of severity of CAD by SYNTAX score (p=0.02). Conclusions: From this clinical study, we can conclude that a moderate correlation exists between level of HbA1c and severity of CAD by SYNTAX score as well as number of vessels involved in diabetics and non-diabetics and HbA1c is a simply measured and reliable marker to predict the severity of CAD. MODERATED POSTER SESSION
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