AFRICA CARDIOVASCULAR JOURNAL OF AFRICA • SMC-PAFCIC Abstracts October 2022 38 affected and are only reported as case presentations in the literature. Clinical presentation we report a case of a 37 years old male patient, without any particular past medical history, who was admitted to our cardiology department for a non-complicated anterior STEMI. Coronary angiography has showed an aneurysmal left anterior descending coronary artery with a fresh thrombus floating in the proximal part and a TIMI3 flow. Etiological investigation did not reveal other atherothrombosis risk factors. Careful questioning and physical examination revealed bipolar ulcers (Oral and anal) with eye and oral dryness, and inflammatory arthralgias. Pathergy test performed was affirmative. Given this body of evidence, the diagnosis of angio-Behçet was retained. Conclusion: Coronary involvement in Behcet Syndrome is extremely uncommon and most of published cases reported acute myocardial infraction in a patient previously diagnosed with Behcet’s disease. Our case report sheds light on an important etiology of acute myocardial infraction in young patients without conventional risk factors atherosclerotic coronary artery disease. Submission ID: 1535 SEX-RELATED DIFFERENCES IN THE INCIDENCE AND PROGNOSIS OF HEART FAILURE WITH IMPAIRED EJECTION FRACTION: AN EXPERIENCE FROM THE UHC IBN ROCHD OF CASBLANCA, MOROCCO (ABOUT 4382 PATIENTS) R.HABBAL MOROCCO Background: Heart failure with reduced ejection fraction (HFrEF) is a fairly common pathology. Several observational studies suggest sexrelated differences in the incidence and prognosis of HFrEF, particularly in the setting of coronary artery disease. Women seem more likely to develop heart failure. Objective: To report the clinical, electrical, echocardiographic, etiological and therapeutic aspects of HFrEF in women versus men. Methods: Retrospective cross-sectional study carried out between March 2018 and March 2022 including all patients over the age of 30 with HFrEF followed in the heart failure therapeutic unit of our department. Data were collected in Excel and analyzed using SPSS 2.0. We studied the clinical, electrical, echocardiographic and etiological aspects of CHF in women compared to men. Results: 2526 women among 4382 HFrEF patients were included, the mean age of women was 62.78±10.31 years versus 62.45±10.15 years in men (P=0.068). 37.8% of women were diabetic vs 26.1% of men (P<0.001), 49.6% were hypertensive vs 32.7% (P<0.001),4% were smokers vs 42.5% (P<0.001). 9.2% had a history of stroke vs 10.6% (P=0.205), 25.8% had a history of myocardial infarction vs 32.6% (P<0.001),5.3% were in end-stage chronic renal failure vs 5.5% (P=0.822). HFrEF in females compared to males was due to ischemic heart disease in 50.6% versus 63.2% (P<0.001). Dyspnea in females compared to males was classified primarily as NYHA class II in 59.7% versus 57.3%. 12.8% of women had atrial fibrillation against 12.5% in men (P=0.860). The mean LVEF was 37.43±15.85% vs. 35.65±10.07% in men(P<0.001). No impact of sex on hospitalization for HF was observed (P=0.867) Conclusion: Myocardial infarction was significantly more frequent in women. This may be explained by a greater prevalence of risk factors for coronary atherosclerosis as well as by female sex. Submission ID: 1537 THE CHANGING FACE OF INFECTIVE ENDOCARDITIS OVER TIME: OVER 30 YEARS COMPARATIVE STUDY CHAWKI KHAWLA, MAAROUFI ANASS, MASCHELL MAHOUNGOU MACKONIA NOEL MOROCCO Introduction: Infective endocarditis (IE) is an evolving disease with a persistently high mortality and morbidity, it is a rare disease for which diagnosis and treatment continue to develop. The purpose of our work is to review our experience with IE and to analyze the evolution in its epidemiologic, clinical and microbiologic characteristics, as well as the outcomes. Methods: The aim of this study is to compare data from a retrospective study conducted in Ibn Rochd Hospital between January 1983 and December 1994, by Bennis and Al based on 157 cases of infectious endocarditis admitted which we referred to as Group A; and 122 cases of infective endocarditis according to Duke criteria admitted to the same center three decades after, from December 2013 to June 2022,which are referred as Group B. Results: Concerning the demographic profile:The mean age of the patients increased, with a mean of 40.3 years in the group B vs 27.5 years in the group A, with a male predominance (62.8% in group A vs 60.7% in group B) Infectious endocarditis secondary to rheumatic valvular heart disease has significantly decreased from 63% of patients in group A to 28.1% in group B. The valves most frequently involved were the mitral and aortic valves in both groups with an increase of mechanical prosthetic valve involvement with 10.4% in group B. A portal of entry was identified in 63%of patients in groupA vs 42% in group B, with a significant decrease of dental-related cases from 64% in group A to 28% in group B.Concerning the pathogens causing IE: In group A, blood cultures were positive in 42% of cases with a predominance of Staphylococci (30%) and coagulase-negative Staphylococci (25.7% of cases) whilst in group B blood cultures were positive in 32%of cases with a predominance of Staphylococci(38.6%) followed by Streptococci (21%) Echocardiography including the transesophageal approach is crucial in the diagnosis of IE by demonstrating specific lesions of IE (abscess or vegetations) in 73.2% of cases in group A and 84% in group B. The major complications of IE in groupA were congestive heart failure CHF (47.8%) or neurological lesions (11.5%) while in group B CHF was noted in 36.4% of cases and 8,3% of neurological lesions. The overall mortality in our series (Group B) was 16% vs 28.7% in group A mostly related to cardiogenic shock. Conclusion: IE remains a highly mortal disease,it’s epidemiology and management are continually changing. These changes should be considered at the time of decision-making in treatment of and prophylaxis for IE. Submission ID: 1539 CHALLENGING PERSISTENT LEFT SUPERIOR VENA CAVA FOR CARDIAC DEVICE IMPLANTATION : TWO CASE REPORTS AND LITERATURE REVIEW EL ASSILI HALA, ABDELILAH BEN EL MAKKI, JAMAL KHEYI, MERYEM BENNANI, HICHAM BOUZELMAT, AATIF BENYASS, ALI CHAIB MOROCCO Background: Persistent Left Superior Vena Cava (PLSVC) is the most common congenital abnormality of the thoracic venous system, it is usually MODERATED POSTER SESSION
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