CARDIOVASCULAR JOURNAL OF AFRICA • SMC-PAFCIC Abstracts October 2022 61 AFRICA Results: 99 patients with IE were collected during the study period. The mean age was 42 years. Complications were observed in 41 patients: cardiac in 61% of patients, embolic in 31% of patients, infectious in 12% of patients, renal in 29% of patients and neurological in 17% of patients. Sixty-eight of the patients (69.3%) underwent surgery: 30 as an emergency and 38 as a delayed operation. The overall mortality was 20%. The analytical study concluded that: the location of endocarditis on mitral prosthesis, persistent fever and duration of antibiotic therapy were independent risk factors for mortality. Conclusion: Infective endocarditis is a serious condition. Her prognoses remain poor. Thus, a multidisciplinary approach should be considered for optimal care and management of patients with the aim of improving their survival. Submission ID: 1723 TREATMENT OF CORONARY BIFURCATION LESIONS WITH TWO-STENT TECHNIQUES: SHORT- AND LONG-TERM OUTCOME IN A NORTH AFRICAN REFERRAL HOSPITAL AMAL BEN SALEM, SELIM BOUDICHE, ZEINEB OUMAYA, ZEINEB JABBARI, MANEL BEN HALIMA, SANA OUALI, FATHIA MGHAITH, MOHAMED SAMI MOURALI TUNISIA Introduction: Angioplasty of coronary bifurcation lesions using 2-stent techniques represent 5% of percutaneous coronary interventions and constitute a real challenge in interventional cardiology. Few data are available in Tunisia regarding this complex strategy. Objective: The aim of this study was to evaluate the immediate and long-term results of these patients. Method: This was a monocentric retrospective observational study including 80 patients who underwent bifurcation lesion angioplasty using twostent technique between January 2014 to June 2020 after excluding the use of bare-metal stents and treatment of intra-stent restenosis. The primary endpoint was target lesion failure (TLF) and to identify possible TLF predictive factors. Secondary endpoint was MACE. A minimum follow-up of 12 months was required. Results: The mean age was 61.4±11 years. The sex ratio was 3. Diabetes was present in 66,3% of patients. Lesions treated were related to distal left main artery bifurcation in 40% and were in relation with a true bifurcation lesion in 93.8% of cases. The indication for 2-stent technique was elective in 85% of cases. Most used technique was T and protrusion in 61.2% of cases. Proximal optimization technique and final kissing balloon were performed in 82.5% and 86.3% of procedures respectively. A procedural success was achieved in all cases. After a median follow-up of 13.5 months [5–35], TLF rate was 18.8%, mainly related to secondary revascularizations (17.5%). Definite and probable stent thrombosis rate was 3.8%. TLF predictive factors were bifurcation angle >90° (p=0.001; OR=21.42 [3.3–60]), side branch reference vessel diameter ≤2.5mm (p=0.005, OR=11.23 [2.07–50.7]), main branch lesion length ≥25mm (p=0.002; OR=6.50 [1.9–21.19]), and main branch severe calcifications (p=0.019; OR=3.98 [1.28–12.63]). Conclusion: Two-stent techniques for treatment of coronary bifurcation lesions represent complex situations associated with increased rate of long-term adverse events despite initial procedural success in all patients. Careful patient selection and rigorous optimization technique could improve long-term outcomes. Submission ID: 1725 DRUG-ELUTING VERSUS BARE-METAL STENTS: IS IT A MATTER OF VESSEL SIZE? SKANDER BOUCHNAG, MOHAMED MEHDI BOUSSAADA, MOHAMED MAJED HASSINE, NIDHAL BOUCHEHDA, MEJDI BEN MESSAOUD, MARWEN MAHJOUB, FETHI BETBOUT, HABIB GAMRA TUNISIA Background: Although drug-eluting stents (DES) for percutaneous coronary intervention have dramatically reduced the incidence of in-stent restenosis. Aim: This study sought to evaluate the safety and effectiveness of drugeluting stents (DES) compared to bare-metal stents (BMS) for patients with large coronary vessels ≥ 3.5 mm. Methods: This is a retrospective comparative study conducted in the cardiology A department of the university hospital Fattouma Bourguiba in Monastir. A total of 77 consecutive patients (80 lesions) who underwent, between October 2003 and March 2014, successful DES implantation were compared to 73 consecutive patients (84 lesions) who were treated with BMS in large coronary vessels ≥ 3.5 mm. MODERATED POSTER SESSION
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