AFRICA CARDIOVASCULAR JOURNAL OF AFRICA • SMC-PAFCIC Abstracts October 2022 66 Results: A total of 34 consecutive patients were included. The mean age was 64.9 ± 10 years. Diabetes was present in 64.7% of patients. Six percent of patients had left ventricular ejection fraction <40%. 97.1% of the patients had true bifurcation lesions. The majority of patients (92%) had low or intermediate SYNTAX Score I. The used techniques were T and protrusion (TAP) (64.7%), followed by DK-Crush (5.9%), Culotte (5.9%), T-stenting (5.9%) and other techniques (2.9%). Proximal optimization technique (POT) was performed in 100% of cases and final kissing balloon in 97.1% of cases. No hemodynamic assistance devices were used in our series. Immediate procedural success was of 100%. At a median follow-up of 13.5 months, target lesion failure (TLF) rate was 29.4% (10 patients) consisting of one cardiac death (1.3%) in relation with a sudden cardiac death considered as a sub-acute probable stent thrombosis and nine cases of in-stent restenosis requiring percutaneous reintervention in seven cases and surgical revascularization in two cases. The major adverse cardiac events (MACE) rate was 35.3% (11 patients) with two non-cardiac deaths in addition to previous described events. Conclusions: Despite initial procedural success in all patients, percutaneous coronary interventions in unprotected LM bifurcation lesions with 2-stents techniques were associated with high long-term rates of TLF and MACE in our population. Submission ID: 1746 TRANSCATHETER AORTIC VALVE IMPLANTATION: INITIAL EXPERIENCE AND ONE-YEAR OUTCOMES FROM A SINGLE INSTITUTE IN TUNISIA BOUDICHE SELIM, BOUSSEMA MOHAMED AMINE, JEBBERI ZEYNAB, YAAKOUBI WAEL, OUMAYA ZEINEB, BEN SALEM AMAL, FARHATI ABDELJELIL, OUALI SANA, MGHAIETH FATHIA, BEN HALIMA MANEL, MOURALI MOHAMED SAMI TUNISIA Background: Transcatheter aortic valve implantation (TAVI) is a novel method to treat selected high-risk patients with aortic stenosis. Implementation of this technique in developing countries is still very limited. This case series aims to report the results of a single center in Tunisia. Methods: Nine consecutive patients with symptomatic severe aortic valve stenosis were planned for transfemoral TAVI using standard procedures between July 2016 and June 2021. Patients were further followed by retrospective record review up to one year to assess efficacy and safety according to the Valve Academic Research Consortium 3 endpoints. Results: Patients had a mean age of 79 ± 5.6 years, two-thirds were women, and all had at least one major cardiovascular risk factor, except for a single case with stenotic degenerated prosthetic valve treated with valve-in-valve TAVI. Another case had a balloon aortic valvotomy for hemodynamic instability as a bridge to TAVI. The mean STS risk score was 7.80% ± 2.05. Eight patients out of nine were treated with self-expanding prosthetic valves while the remaining patient had a balloon-expandable prosthesis. Immediate procedural success was 77.8%. Procedural failure was due to severe aortic regurgitation and hemodynamic instability upon predilatation with subsequent death in one case, and valve embolization in the second case. At 30 days, device success and early safety endpoints reached 66.7% and 55.6% respectively, while clinical safety at one year dropped to 33.3%. Main adverse outcomes on follow-up comprised death due to intracranial hemorrhage and Pacemaker-lead infection, severe anemia, congestive heart failure and arrhythmia. Conclusion: Our case series albeit small, provides insight to both caregivers and policymakers in Tunisia to further extend the scope of application of TAVI in patients with severe aortic stenosis at high surgical risk. Submission ID: 1751 CARDIOVASCULAR MAGNETIC RESONANCE IN CARDIAC AMYLOIDOSIS MERYEM IBEN CHEKROUN, OUSSAMA SIDATY, DOGHMI NAWAL, CHERTI MOHAMMED MOROCCO Background: Cardiac amyloidosis can be diagnostically challenging. Cardiovascular magnetic resonance (CMR) can assess abnormal myocardial interstitium. Methods: It is a retrospective study, involving 40 patients, between January 2017 and December 2019, carried out in Cardiology department B. We included in our study all patients who underwent cardiac MRI in the presence of clinical symptoms and echocardiography signs of cardiac amyloidosis. Results: The average age of the patients was 65+/-12 with a male predominance (68%). Global late gadolinium enhancement was found in 62,5% in amyloid patients. All these patients had greater LV mass. Conclusion: In cardiac amyloidosis, CMR shows a characteristic pattern of global subendocardial late enhancement coupled with abnormal myocardial and blood-pool gadolinium kinetics. Cardiac MRI may proove to have value in diagnosis and treatment follow-up. Submission ID: 1752 NEUROLOGICAL EVENTS ARE STILL A SERIOUS COMPLICATION OF INFECTIVE ENDOCARDITIS HOUDHAYFA HERMASSI, MERIEMDRISSA, NEYROUZ BENGAGI, FAKHER JAOUEDI, MOSLEM BEN ABDALLAH, SYRINE AOUJI, HICHEM MTIMET, HABIBA DRISSA TUNISIA Introduction: Neurological complications constitute the second leading cause of death after hemodynamic complications in infective endocarditis (IE). Purpose: The aim of this work was to study the clinical, bacteriological, therapeutic and evolutionary aspects of these neurological complications. Methods: We conducted a retrospective study of 250 cases of IEs hospitalized between 1996 and 2021. We included cases of certain IE according to Dukes criteria. Neurological complications accounts for 88 patients (35%). Our population was divided into 2 groups: group 1 (IE with neurological complications) composed of 88 patients and group 2 (IE without neurological complications) including 162 patients. Characteristics of each groups were compared. MODERATED POSTER SESSION
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