AFRICA CARDIOVASCULAR JOURNAL OF AFRICA • SMC-PAFCIC Abstracts October 2022 68 Methods: We carried out a study in the hemodialysis units of Marrakech’s Mohammed VI University Hospital, Morocco, over a six-month period in 2020, we consecutively recruited consenting adult patients on maintenance hemodialysis for at least three months. A 24-hour Holter ECG monitor was placed just before dialysis. After the examination of 24-hour Holter ECG, especially cardiac arrythmias, with clinical characteristics and biochemical data was analyzed. Results: 56 patients were retained. The average age was 49 ± 17.32 years, and women made up 54% of the workforce. The main comorbidity found was hypertension (24 patients, 43%). On Holter ECG ventricular extrasystoles (ESV) were present in 15.19% of cases. Supraventricular extrasystoles (ESSV) were found in 11.04% of patients with a significant correlation with electrolyte abnormalities generated by dialysis as a significant difference in serum potassium level change (5,66 VS 3,69 mEq/l: p<0.05). Other electrocardiographic abnormalities were captured in perhemodialysis (QTc interval lengthening, P wave duration shortening, PR interval lengthening). Conclusion: Through the results of our study of the arrhythmogenic profile of hemodialysis in ESRD, we underlined the “SAFETY” of hemodialysis, while the other electrocardiographic abnormalities that appeared during the dialysis session are the results of per-dialytic electrolyte disturbances, but without any generation of a serious cardiac arrhythmia, these detected abnormalities could allow nephrologists to modify dialysis prescription in response to minute-to-minute changes on dialysate. Submission ID: 1759 FEMALE PATIENTS WITH MYOCARDIAL INFARCTION AND NON OBSTRUCTIVE CORONARY ARTERIES (MINOCA): CLINICAL CHARACTERISTICS, IN-HOSPITAL COMPLICATIONS AND LONG-TERM MORTALITY AZAIEZ FARES, JAOUED FAKHER, KHALIFA ROUAIDA, DRISSA MARIEM, MLIK AHMED, LAGHA ELYES, BEN ROMDHANE RIM, BACHRAOUI KAOUTHER, TLILI RAMI, BEN AMEUR YOUSSEF TUNISIA Introduction: The clinical manifestations of myocardial infarction (MI) with normal arteries on angiography is known as myocardial infarction with nonobstructive coronary arteries (MINOCA). As compared to MI due to obstructive coronary artery disease (MI-CAD), female gender is over-represented in MINOCA. The aim of our study was to assess the clinical characteristics, in-hospital complications and long-term mortality of female patients with MINOCA compared to female patients with MI-CAD. Methods: This was a retrospective study of women hospitalized for MI at the cardiology department of Mongi Slim Hospital over a period of 2 years and 6 months (July 2019 - December 2021). All patients underwent clinical examination, echocardiography and coronarography. Results: We enrolled 191 patients in the study. The mean age was 61 years. An obstructive coronary due to atherosclerotic cause was found in 161 (84%) while MINOCA was found in 30 patients (16%). The mean age of the MINOCA group was 50 years significantly younger than the MI-CAD group (64 years) (p<0.05). Among risk factors, a significant difference was found in the MINOCA group compared to the CAD group concerning the history of hypertension (15 (50%) vs 114 (71%), p < 0.05 ), diabetes mellitus (5 (17%) vs 113 (70%), p <0.01) and dyslipidemia (3 (10%) vs 50 (31%), p< 0.05) while no significant difference was found in the history of smoking (8 (27%) vs 42 (26%)), obesity (7 (23%) vs 31 (19%)) and family CAD (4 (13%) vs 12 (7%)). 15 (50%) patients of the MINOCA group were postmenopausal on admission significantly less than the CAD group (140, 87%). ST segment elevation myocardial infarction was found in 8 (27%) cases in the MINOCA group and in 60 (36%) cases in the CAD group (p>0.05) with no significant difference. In-hospital complications in the MI-CAD group have been significantly higher than in the MINOCA group (39 (24%) vs 3 (10%) p<0.05). 6 cases of in-hospital mortality have been noted in the MICAD group while no death have been recorded in the MINOCA group. Concerning long term mortality, 13 deaths have been recorded in the MI-CAD group while no deaths in the MINOCA group were recorded. Conclusion: Presentation with MINOCA was more common in younger patients and tended to have fewer cardiac risk factors than patients with MI-CAD. Patients with MINOCA had different outcomes compared to MI-CAD patients, including lower in-hospital complications and better long-term mortality. Submission ID: 1761 MYOCARDIAL INFARCTION IN YOUNG WOMEN: CLINICAL PROFILE AND LONG TERM OUTCOMES AZAIEZ FARES, JAOUED FAKHER, KHALIFA ROUAIDA, DRISSA MARIEM, MLIK AHMED, LAGHA ELYES, BEN ROMDHANE RIM, BACHRAOUI KAOUTHER, TLILI RAMI, BEN AMEUR YOUSSEF TUNISIA Introduction: Myocardial infarction (MI) in young women is rare but its incidence is increasing and constitutes a challenging economic issue. Given that coronary artery disease in young women has epidemiological, clinical, and prognostic particularities, it would be important to identify them in order to be able to act in a more targeted manner in primary and secondary prevention and to improve therapeutic management. Our study aimed to determine the clinical, electrical, prevalence of in-hospital complications and long-term mortality in young women with acute myocardial infarction. Methods: This was a retrospective study including women aged between 18 and 50 years hospitalized for MI at the cardiology department of Mongi Slim Hospital over a period of 2 years and 6 months (July 2019 - December 2021). All patients underwent clinical examination, echocardiography and coronarography. Results: We enrolled 44 patients in the study. The mean age was 44years. The most frequent cardiovascular risk factors were hypertension (52%) followed by smoking (45%) and diabetes mellitus (43%). Dyslipidemia was noted in 23% (10 cases). Obesity was noted in 25% (11) patients. History of autoimmune disease was present in 11% (5). 12 patients (28%) were postmenopausal on admission. Typical angina was the main circumstance of MI in 40 (91%) patients associated with other signs in 10 (23%) cases. ST segment elevation myocardial infarction was reported in 15 (34%) cases. Inferior MI in 7 patients (16%) was the most common type, followed by anterior MI in 6 (14%) patients and non-ST segment elevation MI in 27 (61%). 25 patients (57%) had preserved left ventricular ejection fraction post MI. Concerning biological data, 9 patients (25%) had anemia and 6 (14%) had moderate chronic kidney disease. In-hospital complications occurred in 11% of cases (5 patients) and no inhospital mortality was noted. On long-term mortality, only one death was recorded. Conclusion: The incidence of MI in young women is rising along with rising lifestyle risk factors and higher rates of diabetes, hypertension and smoking. MODERATED POSTER SESSION
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