AFRICA CARDIOVASCULAR JOURNAL OF AFRICA • SAHS Biennial Congress 16-18 September 2022 56 Submission ID: 1367 Introduction The impact of chronic kidney disease (CKD) and hemodialysis (HD) on heart function is not fully understood. Purpose: Assess the influence of different grades of chronic nephropathy and HD on the cardiac function using myocardial deformation: Longitudinal global strain (LGS) Methods Descriptive cross-sectional study conducted between January 2017 and January 2018, concerning patients followed for CKD sent for cardiac evaluation. The patients were classified into 3 subgroups (Control: without CKD; Medium to advanced CKD: stages 3, 4 or 5, and terminal CKD on HD. The systolic function of the LV was evaluated by echocardiography with the analysis of the LGS. Results The study included 100 patients, According to the subgroups: 33 did not have CKD (control), 27 had moderate to advanced CKD (stages 3, 4 or 5) and 40 had terminal CKD on HD. There was no significant difference in gender, age and LVEF among the groups. Compared to control group, the absolute value of SLG was decreased in the CKD groups, this decrease is parallel to the decline in renal function. In addition, compared to moderate CKD patients, LV systolic function was better in patients with CKD on HD. Conclusion Myocardial strain analysis is much more sensitive for predicting and detecting LV systolic dysfunction in patients with CKD. The decline in kidney function parallels the deterioration in heart function which may indicate that toxins play an important role in LV dysfunction, HD helps clarify toxins and improve LV function. Name: Presenting Author Information Article Category Abstract Title CHU Ibn Rochd, Casablanca, Morocco meryelmousaid@gmail.com English Abstract Basic Sciences Influence of different grades of CKD and HD on cardiac function using myocardial strain: Longitudinal Global Strain Author Affiliation: Email: Meriem EL Mousaid Authors Name & Surname Title Expertise Affiliation Email Country Meriem EL Mousaid Résidente Cardiologie CHU Ibn Rochd, Casablanca meryelmousaid@gmail.com Morocco Hatim Hajar Résidente Cardiologie CHU Ibn Rochd, Casablanca Morocco Hamdani Zeyneb Résidente Cardiologie CHU Ibn Rochd, Casablanca Morocco Habbal Rachida Professeur agrégée Cardiologie CHU Ibn Rochd, Casablanca Morocco POSTER PRESENTATION
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