CARDIOVASCULAR JOURNAL OF AFRICA • Volume 34, No 2, May/June 2023 80 AFRICA 35. Dawn B, Guo Y, Rezazadeh A, Wang O-L, Stein AB, Hunt G, et al. Tumor necrosis factor-α does not modulate ischemia/reperfusion injury in naive myocardium but is essential for the development of late preconditioning. J Molec Cell Cardiol 2004; 37(1): 51–61. 36. Bolli R, Li Q-H, Tang X-L, Guo Y, Xuan Y-T, Rokosh G, et al. The late phase of preconditioning and its natural clinical application – gene therapy. Heart Fail Rev 2007; 12(3–4): 189–199. 37. Lecour S, Rochette L, Opie L. Free radicals trigger TNFα-induced cardioprotection. Cardiovasc Res 2005; 65(1): 239–243. 38. Pedretti S, Brulhart-Meynet M-C, Montecucco F, Lecour S, James RW, Frias MA. HDL protects against myocardial ischemia reperfusion injury via miR-34b and miR-337 expression which requires STAT3. PloS One 2019; 14(6). HeFSSA Specialist Treatment and Device Therapy Course 25–26 November 2022 Capital on Park Hotel, Sandton The inaugural HeFSSA specialist treatment and device therapy course was held in Sandton, Gauteng, on 25 and 26 November 2022. The meeting focused on the importance of a multi-therapy approach to heart failure treatment and demonstrations of practical and clinical application of guideline recommendations at a cardiologist level. In-room international faculty included Dr Anders Barasa (Rigshospitalet-Glostrup in Copenhagen, Denmark) as well as local expert faculty, namely: Prof Karen Sliwa, Prof Eric Klug, Prof Nash Ranjith, Prof Nqoba Tsabedze, Prof Ntobeko Ntusi, Dr Martin Mpe, Dr Jens Hitzeroth, Dr Vinod Thomas, Dr Farouk Mamdoo, Dr Andrew Thornton, Dr Tsungai Chipamaunga, Dr Philasande Mkoko and Dr Sandra Pretorius. The course accommodated 72 delegates affiliated with hospitals, universities and institutions in South Africa, and a few from Namibia and Zimbabwe. The HCP delegates were equally from the public and private sectors in South Africa. The inaugural HeFSSA heart failure specialist meeting equipped cardiologists in South Africa with the knowledge to treat heart failure by providing educational essentials to improve patient outcomes. The meeting allowed the heart failure community to share best practices and the benefits of their experience with peers. As a result, the academic programme focused intensely on the efficacy and outcomes of chronic heart failure treatment and device therapies by covering topics that inform diagnosis, imaging, pharmaceutical and device therapies, and lifestyle changes. Esteemed key opinion leaders from private and public sectors led these sessions, welcoming input, questions and deliberations from the delegates. The academic programme was highly beneficial to and attended by cardiologists, cardiology fellows, electrophysiologists, specialist physicians, clinical technicians and allied health professionals with a special interest in heart failure. The plenary sessions led to stimulating discussions where delegates and faculty could engage in high-impact learning, stimulating reflections and networking across specialities. • Plenary session 1 was chaired by Prof Karen Sliwa and included: an evaluation by Prof Eric Klug on the treatment success in heart failure; recommendations on diet and exercise for heart failure patients by Dr Sandra Pretorius; and a panel discussion led by Dr Martin Mpe, Prof Ntobeko Ntusi and Prof Eric Klug on the practical guidelines to prescribing HFrEF remodelling therapy. • Plenary session 2 covered three lectures chaired by Prof Eric Klug. The lectures unpacked the deliberations on ARNI as firstline therapy (Prof Nash Ranjith), insight into the prevention, treatment and early administration of SGLT2i (Prof Ntobeko Ntusi) and an outline on appropriate management of heart failure and arrhythmia in the peripartum period (Prof Karen Sliwa). • Plenary session 3 was chaired by Dr Martin Mpe. The session included the chronological perspective on landmark heart failure trials (1980–2022) by Dr Anders Barasa; an update on new concepts in cardiac resynchronisation delivered by Dr Vinod Thomas; and an integrated two-part talk on QRS duration versus QRS morphology in Dr Philasande Mkoko’s didactic lecture and Dr Andrew Thornton’s practical application and case presentations. Continued on page 88… From left to right: Dr Charle Viljoen, Dr Anders Barasa (international faculty, Denmark and Kenya), Dr Jens Hitzeroth, Dr Farouk Mamdoo, Dr Philasande Mkoko, Dr Vinod Thomas, Prof Nqoba Tsabedze (convener), Dr Chishala Chishala, Dr Tsungai Chipamaunga and Dr Martin Mpe.
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