| EDITORIAL | 5 |
| CARDIOVASCULAR TOPICS | 11 |
| The simplified modification-of-diet-in-renal-disease equation as a predictor of renal function after coronary artery bypass graft surgery | 11 |
| Tracking of lipids in schoolchildren: a four-year follow-up, population-based study in Sousse (Tunisia) | 15 |
| The effect of ambient temperature on blood pressure in a rural West African adult population: a cross-sectional study | 19 |
| Relationship between left ventricular geometric pattern and systolic and diastolic function in treated Nigerian hypertensives | 23 |
| A prevalence of cardiometabolic risk factors among a rural Yoruba south-western Nigerian population: a population-based survey | 28 |
| Cardiac abnormalities and facial anthropometric measurements in children from the Free State and Northern Cape provinces of South Africa with chromosome 22q11.2 microdeletion | 34 |
| The effect of hypoxia-inducible factor 1-alpha on hypoxia-induced apoptosis in primary neonatal rat ventricular myocytes | 39 |
| Is fenofibrate a cost-saving treatment for middle-aged individuals with type 2 diabetes? A South African private-sector perspective | 45 |
| CASE REPORT | 49 |
| YOUR LIFE AND YOUR HEART | 52 |
| DRUG TRENDS | 51 |
| Insulin glargine and the risk of cancer | 51 |
| Treating hypertensive patients with coronary artery disease: renewed interest in INVEST | 55 |
| The ultimate anticoagulants | 57 |
| Stop press focus on RE-COVER study | 61 |
| 24-hour powerful blood pressure lowering – essential for target organ protection | 63 |
| More than 50% reduction in ischaemic stroke with rosuvastatin in JUPITER study | 66 |