CARDIOVASCULAR JOURNAL OF AFRICA • Vol 23, No 3, April 2012
AFRICA
159
33. Mittal P, Espinoza J, Hassan S, Kusanovic JP, Edwin SS, Nien JK,
et al
.
Placental growth hormone is increased in the maternal and fetal serum
of patients with preeclampsia.
J Matern Fetal Neonatal Med
2007;
20
:
651–659.
34. Robinson CJ, Johnson DD, Chang EY, Armstrong DM, Wang W.
Evaluation of placenta growth factor and soluble Fms-like tyrosine
kinase 1 receptor levels in mild and severe preeclampsia.
Am J Obstet
Gynecol
2006;
195
: 255–259.
35. Wikstrom AK, Larsson A, Eriksson UJ, Nash P, Norden-Lindeberg S,
Olovsson M. Placental growth factor and soluble FMS-like tyrosine
kinase-1 in early-onset and late-onset preeclampsia.
Obstet Gynecol
2007;
109
: 1368–1374.
36. Levine RJ, Qian C, Maynard SE, Yu KF, Epstein FH, Karumanchi SA.
Serum sFlt1 concentration during preeclampsia and mid trimester blood
pressure in healthy nulliparous women.
Am J Obstet Gynecol
2006;
194
: 1034–1041.
37. Shibata E, Rajakumar A, Powers RW, Larkin RW, Gilmour C, Bodnar
LM,
et al
. Soluble fms-like tyrosine kinase 1 is increased in preeclamp-
sia but not in normotensive pregnancies with small-for-gestational-age
neonates: relationship to circulating placental growth factor.
J Clin
Endocrinol Metab
2005;
90
: 4895–4903.
38. Maynard S, Epstein FH, Karumanchi SA. Preeclampsia and angiogenic
imbalance.
A Rev Med
2008;
59
: 61–78.
39. Savvidou MD, Yu CK, Harland LC, Hingorani AD, Nicolaides KH.
Maternal serum concentration of soluble fms-like tyrosine kinase 1 and
vascular endothelial growth factor in women with abnormal uterine
artery Doppler and in those with fetal growth restriction.
Am J Obstet
Gynecol
2006;
195
: 1668–1673.
40. Karumanchi SA, Bdolah Y. Hypoxia and sFlt-1 in preeclampsia: the
‘chicken-and-egg’ question.
Endocrinology
2004;
145
: 4835–4837.
41. Karumanchi SA, Epstein FH. Placental ischemia and soluble fms-like
tyrosine kinase 1: cause or consequence of preeclampsia?
Kidney Int
2007;
71
: 959–961.
42. Zhou Y, McMaster M, Woo K, Janatpour M, Perry J, Karpanen T,
et al
.
Vascular endothelial growth factor ligands and receptors that regulate
human cytotrophoblast survival are dysregulated in severe preeclampsia
and hemolysis, elevated liver enzymes, and low platelets syndrome.
Am
J Pathol
2002;
160
: 1405–1423.
43. Smith GC, Crossley JA, Aitken DA, Jenkins N, Lyall F, Cameron AD,
et al.
Circulating angiogenic factors in early pregnancy and the risk
of preeclampsia, intrauterine growth restriction, spontaneous preterm
birth, and stillbirth.
Obstet Gynecol
. 2007;
109
: 1316–1324.
44. Smith GC, Wear H. The perinatal implications of angiogenic factors.
Curr Opin Obstet Gynecol
2009;
21
: 111–116.
45. Hirokoshi K, Maeshima Y, Kobayashi K, Matsuura E, Sugiyama H,
Yamasaki Y,
et al.
Elevated serum sFlt-1/Ang-2 ratio in women with
preeclampsia.
Nephron
2007;
106
: c43–50.
46. Zhou CC, Ahmad S, Mi T, Abbasi S, Xia L, Day MC,
et al
.
Autoantibody from women with preeclampsia induces soluble Fms-like
tyrosine kinase-1 production via angiotensin type 1 receptor and
calcineurin/nuclear factor of activated T-cells signaling.
Hypertension
2008;
51
: 1010–1019.
47. Irani RA, Xia Y. The functional role of the renin-angiotensin system in
pregnancy and preeclampsia.
Placenta
2008;
29
: 763–771.
48. Anguiano-Robledo L, Reyes-Melchor PA, Bobadilla-Lugo RA, Perez-
Alvarez VM, Lopez-Sanchez P. Renal angiotensin-II receptors expres-
sion changes in a model of preeclampsia.
Hypertens Preg
2007;
26
:
151–161.
49. Hubel CA, Wallukat G, Wolf M, Herse F, Rajakumar A, Roberts JM,
et al.
Agonistic angiotensin II type 1 receptor autoantibodies in post-
partum women with a history of preeclampsia.
Hypertension
2007;
49
: 612–617.
50. Herse F, Verlohren S, Wenzel K, Pape J, Muller DN, Modrow S,
et al
.
Prevalence of agonistic autoantibodies against the angiotensin II type
1 receptor and soluble fms-like tyrosine kinase 1 in a gestational age-
matched case study.
Hypertension
2009;
53
: 393–398.
51. Roberts CB, Rom L, Moodley J, Pegoraro RJ. Hypertension-related
gene polymorphisms in pre-eclampsia, eclampsia and gestational
hypertension in black South African women.
J Hypertens
2004;
22
:
945–948.
52. WangY, GuY, Lewis DF. Endothelial angiotensin II generation induced
by placenta-derived factors from preeclampsia.
Reproduct Sci
2008;
15
: 932–938.
53. Doering TP, Haller NA, Montgomery MA, Freeman EJ, Hopkins MP.
The role of AT1 angiotensin receptor activation in the pathogenesis of
preeclampsia.
Am J Obstet Gynecol
1998;
178
: 1307–1312.
54. Smith RA, Baker PN. Risk factors, prevention and treatment of hyper-
tension in pregnancy.
Minerva Ginecolog
2005;
57
: 379–388.