| FROM THE EDITOR'S DESK | 7 |
| LETTER TO THE EDITOR | 7 |
| CARDIOVASCULAR TOPICS | 8 |
| CEPHEUS SA: a South African survey on the under-treatment of hypercholesterolaemia | 8 |
| The R563Q mutation of the epithelial sodium channel beta-subunit is associated with hypertension | 15 |
| Echocardiographic findings in children with Marfan syndrome | 19 |
| The relationship between indices of iron status and selected anthropometric cardiovascular disease risk markers in an African population: the THUSA study | 23 |
| Effect of short-term isometric handgrip training on blood pressure in middle-aged females | 31 |
| Global cardiovascular risk profiles of untreated hypertensives in an urban, developing community in Africa | 35 |
| CASE REPORTS | 42 |
| Anomalous origin of the left pulmonary artery from the ascending aorta in two children | 42 |
| Isolated tricuspid valve prolapse: identification using two- and three-dimensional echocardiography and transoesophageal echocardiography | 46 |
| Double-chambered right ventricle: an uncommon congenital heart disease. Case report | 48 |
| CARDIO NEWS | 52 |
| INDUSTRY NEWS | 53 |
| DRUG TRENDS | 57 |
| Namibia becomes first country in Africa to launch dabigatran etexilate for atrial fibrillation | 57 |
| New insights and results from the RE-LY trial | 58 |