CARDIOVASCULAR JOURNAL OF AFRICA • SMC-PAFCIC Abstracts October 2022 19 AFRICA after exclusion of coronary artery disease. LVEF was measured at enrollment and remeasured periodically during a mean follow-up of 26 ± 8 months. Patients were classified as responders, partial responders, or non-responders based on their LVEF recovery. Serious adverse cardiac events were also recorded during the follow-up period. Results Treatment of HF had a response rate of 22%, a partial response rate of 33%, and a nonresponse rate of 45%. Comparing responders, partial responders and non-responders, responders had a lower rate of cumulative cardiac events (8%, 22% and 44%, respectively; p 0.003) (Fig.1). The percentage of responders decreased with increasing time between the end of chemotherapy and the start of HF treatment; no complete recovery of LVEF was observed after 11 Submission ID: 1392 A SEVERE NON-ISCHEMIC HYPOKINETIC CARDIOMYOPATHY REVEALING AN AXIAL ANKYLOSING SPONDYLITIS: A CASE REPORT OUMAYMA HATTAB, NOHA EL OUAFI MOROCCO Background Ankylosing spondyloarthritis is a chronic rheumatis disease that affects the vertebral colon and sacroiliac joint primarily, and peripheral joints secondly. Meanwhile it can have an extra articular manifestations such as cardiac, pulmonary, ophthalmologic, and neurologic. Cardiovascular involvement is a well-known side effect of AS, associated to a higher mortality and morbidity rate, the disease spectrum is large, comprising aortitis, valvular heart disease, conduction abnormalities, and cardiomyopathy. Interestingly, dilated cardiomyopathy has been associated with ankylosing spondylitis and reported in only in a few cases in the literature, but the pathophysiological mechanisms of this association remain poorly understood. Here we report a case of a 50 year old male without additional cardiovascular risk factors who was admitted to our cardiology department to manage an acute heart failure, his routine blood test were normal, he had normal coronary arteries on cardiac catheterization and his transthoracic echocardiography showed a newly severe hypokinetic cardiomyopathy, further investigations revealed ankylosing spondyloarthritis (AS) fortuitously diagnosed. He responded well to diuretics and non-steroidal anti-inflammatory drugs. The patient reported an improvement in his cardiac and joints symptoms, and repeat echocardiography showed an improvement Submission ID: 1397 OSTIAL STENTING VERSUS LEFT MAIN CROSSOVER STENTIG IN ISOLATED OSTIAL LEFT ANTERIOR DESCENDING ARTERY DISEASE AHMED MAKNI, TARAK ELLOUZE, SALMA CHARFEDDINE, RANIA HAMMAMI, AFIF REKIK, AMINE BAHLOUL, SOUAD MALLEK, FATEN TRIKI, MOUNA HENTATI, AIMAN GHRAB, LEILA ABID TUNISIA Introduction: Ostial lesion of left anterior descending coronary artery (LAD) remains challenging because of the unpredictable involvement of distal left main coronary artery (LM) which has been already suggested in intravascular ultrasound studies . Objective: We evaluated the impact on short, mid and long-term outcomes of ostial LAD disease treated by means of ostial stenting (the floatingstent) or left main (LM)-to-LAD cross-over stenting Methods: We included all patients ,between the 1st October 2012 and the 1st May 2018, with significant and isolated stenosis of the ostial LAD (ostium or the first 3 mm at the origin of the LAD) objectified at the coronary angiography and treated by percutaneous coronary intervention (PCI). A stenosis of the ostial LAD was considered significant if it is judged to be ≥50% at the coronary angiography. The complexity of the lesions and coronary disease was evaluated months (Fig. 2). Conclusion AC-CMP early detection and appropriate HF treatment can lead to an improvement in LVEF and a decrease in cardiac events. This highlights the importance of establishing a monitoring pathway using biomarkers and echocardiography. of his ejection fraction. AS is part of the group of chronic inflammatory that can have many extra articular manifestations including the cardiac injuries with poor outcomes. This association which remain rare and not sufficiently studied. Among this case we aim is to highlight the cardiac injuries in patient with ankylosing spondylitis (AS). Figure 2: Percentage of Responders Based on Time between Anthracycline end and HF Therapy initiation MODERATED POSTER SESSION
RkJQdWJsaXNoZXIy NDIzNzc=