AFRICA CARDIOVASCULAR JOURNAL OF AFRICA • SMC-PAFCIC Abstracts October 2022 50 we had an accuracy of 85.74%. The results of the other processing methods are resumed in table 1. Conclusion: Keyframe extraction using image processing seems to be efficient and can be used for a fully automated coronary angiogram analysis. Submission ID: 1634 EPIDEMIOLOGY AND PROGNOSIS OF COAGULASENEGATIVE STAPHYLOCOCCAL ENDOCARDITIS SAMIA EJJEBLI, ANAS MAAROUFI, GHALI BENNANI, MOHAMED KHALDI, SALIM AROUS MOROCCO Introduction: Coagulase-negative staphylococci (CoNS) is recognized as a common pathogen responsible for infective endocarditis IE occurs mostly in patients with intra cardiac devices or prosthetic valves. becoming an important cause of native valve endocarditis too (NVE). Virulence and antibiotic resistance of CoNS affects IEoutcome. Methods and Materials: The medical records of 115 patients clinically diagnosed with IE were reviewed for clinical and microbiology data admitted between January 2014 to december 2018. Blood cultures were detected by using Bactecaerobic / anaerobic /mycoticbottles. Results: There were 115 case of infective endocarditis admitted to our service during the period of study 26/115 cases were positive for bacterial pathogens. The isolates were identified as Coagulase negative staphylocciin 11 cases representing 9.5% of all IE, 45% were related to ICD (4 hemodialysis catheter in RA, 1 pacemaker), 9% were prosthetic Valve endocarditis, 45% were native valve endocarditis. 45% patients, isolates were resistant to methicillin and cephalosporin, with a higher rate in ICD IE (80%); tricuspid valve was the most involved 36%, vegetations were present in 81% cases, with one case of multiple abcesses, 54% patients required surgery, including almost all patients with ICD IE. Mortality rates were 9% related to advanced access dessimination, length of hospital stay were 41 days in cases related to resistant species and 29 days in sensible ones, vancomycin was used in 72% of cases. Conclusion: CoNS IE is mainly associated with ICD, surgical management improve prognosis and mortality is more related to virulence and local dessimination than resistance to Penincillin as long itis sensible to vancomycin. Submission ID: 1638 HIGH-GRADE ATRIO-VENTRICULAR BLOCK IN YOUNG SUBJECTS SECONDARY TO VAGAL HYPERACTIVITY (ABOUT 3 CASES) KARIM FATIHA, HAMINE YOUSRA, TLOHI IMANE, ELAMRAOUI ASMAA MOROCCO Introduction: Conduction disorders in young subjects can have several etiologies. Vagal hyperactivity, which corresponds to excessive activity of the parasympathetic system, is a frequent cause, hence the interest of exploring the autonomic nervous system (ANS) in young patients with conductive disorders. Patients and methods: We report the case of 3 young patients aged 22, 28 and 32 years, with no particular history, followed in the cardiology department at the Casablanca University Hospital. Who presents faintness and dizziness see and several episodes of syncope in two of these patients. The clinical examination is normal apart from arterial hypotension, the baseline ECG was normal in 2 patients and showing a BAV 2/1 in the 3rd patient. The holter ECG showed nocturnal 2/1 atrioventricular block (AVB). ANS tests include deep breathing, isometric contraction, hyperventilation, orthostatic test, and mental stress. Showed a very high vagal response, a normal central and peripheral alpha and beta sympathetic response and a severe decrease in supine blood pressure in all 3 patients Marked vagal hyperactivity is responsible for BAV. The patients were put under MHD and Ethyl-phenyl-ephrine with good evolution. Discussion: The parasympathetic innervation is distributed mainly to the sinus node, atrioventricular node and, to a lesser extent, to the biauricular and ventricular myocardium. The sympathetic innervation concerns the whole of the heart with a distribution as marked at the level of the ventricle as elsewhere. Parasympathetic modulation has a negative chronotropic effect. At rest, the HR is mainly under the vagal brake. Acetylcholine (ACh) released by parasympathetic neurons decreases the frequency of discharge at the level of the sinus node. It also has a negative effect on the release of norepinephrine and attenuates the response to adrenergic stimulation. Cardiovascular modulation by the parasympathetic system is very rapid, while that of the sympathetic system requires a longer time. Manifestations related to vagal hyperactivity can take many forms. The set of clinical manifestations is called vagal syndrome. Conclusion: Vagal hyperactivity is a common cause of high-grade BAV that needs to be explored by ANS tests for more adequate management. Submission ID: 1642 OUTCOMES IN ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION TREATED WITH PRIMARY PERCUTANEOUS CORONARY INTERVENTION OR PHARMACOINVASIVE STRATEGY IN A SINGLE TUNISIAN CENTER DERWICH MOHAMED, DENGUIR HICHEM, ABID SLIM, BATTRAWI AHMED TUNISIA Objective: The Primary angioplasty in myocardial infarction (PAMI) is the preferred reperfusion strategy for ST-segment elevation myocardial MODERATED POSTER SESSION
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