CARDIOVASCULAR JOURNAL OF AFRICA • SMC-PAFCIC Abstracts October 2022 67 AFRICA Results: Neurological complications were: ischemic stroke in 65 patients, hemorrhagic stroke in 8 patients and cerebral abscess in 15 patients. There was no significant difference in age and sex between the 2 groups. Neurological complications occurred more frequently in prosthetic endocarditis (p = 0.04) than in native valve disease. The infectious syndrome was more observed in case of neurological complications (group 1: 97%, group 2 64.74%, p = 0.05). Staphylococcal endocarditis occur more in group 1 (40.78% versus 15.64%, p = 0.01). The presence of the vegetations ( 23,73%, versus 15%, p = 0.5), abscesses (10%, versus 8%, p = 0.6), severe regurgitation (23 .73%, versus 13%, p = 0.3 ) were more common in neurological complications. Prognosis was worser in case of neurological localizations with more occurrence of cardiac failure (40%, verus 12.55%, p = 0.04), more need to early surgery (50%, versus 41%, p = 0.6) and higher mortality (34.78%, versus 15.25%, p = 0.001) Conclusion: Neurological complications are as serious complication of IE and constitute a life-threatening condition. Their occurrence may change the management strategy. Submission ID: 1753 USEFULNESS OF 64-SLICE MULTIDETECTOR COMPUTED TOMOGRAPHY TO DETECT CORONARY DISEASE IN PATIENTS PRIOR TO CARDIAC VALVE SURGERY HOUDHAYFA HERMASSI, MERIEMDRISSA, NEYROUZ BENGAGI, FAKHER JAOUEDI, MOSLEM BEN ABDALLAH, SYRINE AOUJI, HICHEM MTIMET, HABIBA DRISSA TUNISIA Introduction: Preoperative identification of significant coronary artery disease (CAD) in patients prior to valve surgery requires systematic invasive coronary angiography. Purpose: The purpose of this current study was to evaluate wheither exclusion of CAD by multi-detector CT (MDCT) might potentially avoid systematic cardiac catheterization in patients prior to cardiac surgery. Methods: Thirty patients were included between june 2019 and 2021, they underwent 64-slice multi-detector computed tomography (MDCT) before invasive quantitative coronary. They were 19 females and 11 males, aged from 50 to 75 years, they were asymptomatic of chest pain but they have a cardiovascular risk factor. They were scheduled for surgical procedures: aortic valve replacement for severe aortic stenosis (15 patients), aortic root surgery and aortic valve replacement for aortic root aneurysm (5 patients) and mitral replacement for severe regurgitation (10 patients). They underwent 64-slice MDCT before invasive quantitative coronary. The MDCT showed a normal coronary artery in 16 patients, a non-significant stenosis in 7 patients ,and significant stenosis in7 patients; Coronary angiography confirmed the results of MDCT in 28 patients. Two patients and 8 segments were not correctly identified by MDCT because of artifact and especially due to severe calcifications which overestimate a moderate stenosis (< 50% by quantitative coronary angiography). Conclusion: 64-slice MDCT is potentially useful for detecting CAD in patients prior to valve surgery. By selecting only those patients with positive MDCT findings to undergo invasive coronary angiography, it could avoid cardiac catheterization in a large number of patients without CAD. Submission ID: 1754 ANGIOGRAPHIC FEATURES OF MYOCARDIAL INFARCTION IN YOUNG WOMEN AZAIEZ FARES, JAOUED FAKHER, KHALIFA ROUAIDA, DRISSA MARIEM, MLIK AHMED, LAGHA ELYES, BEN ROMDHANE RIM, BACHRAOUI KAOUTHER, TLILI RAMI, BEN AMEUR YOUSSEF TUNISIA Introduction: MI (myocardial infarction) in young women is rare .Though, there is limited data about MI in this category of patients. It has been observed that the angiographic profile of MI and its causes are quite different in young women as compared to older age. Our study was carried out to study the angiographic profile and etiologies of myocardial infarction in young women. Methods: This was a retrospective study of women aged between 18 and 50 years hospitalized for MI at the cardiology department of Mongi Slim Hospital over a period of 2 years and 6 months (July 2019 – December 2021). All patients underwent clinical examination, echocardiography and coronarography. Results: A total of 44 female patients were enrolled in our study. The mean age of presentation was 44.2 years. ST segment elevation myocardial infarction was reported in 15 cases (34%). Primary angioplasty was performed in 8 (53%) cases while thrombolysis was done in 7 patients (46%), out of which it was successful in 3 (20%) patients. An obstructive coronary finding due to an atherosclerotic cause was found in 25 cases (57%). A single-vessel disease predominated among 25 cases (57%). A coronary artery dissection was at the origin of MI in 11 (25%) patients. The left anterior descending artery was the most affected vessel by the coronary artery dissection in 7 (64%) cases. MI with normal or recanalized coronaries was present in 8 (18%) cases, 6 (75%) of whom underwent myocardial MRI. Myocarditis and MI with recanalized coronaries were found in 3 patients each, followed by TakoTsubo (1 patient) and Prinzmetal (1 patient). 27 (61%) patients had percutaneous coronary angioplasty and the rest of patients received medical treatment only. Conclusion: In our study, plaque-related MI, coronary artery dissection and myocarditis were the main causes of MI in young women. Nonatherosclerotic causes of MI should be investigated in patients without obstructive coronary since non-diagnosis can result in higher morbidity. Submission ID: 1756 CARDIAC ARRYTHMIAS IN HEMODIALYSIS PATIENTS MERIEM LAMHANI, M ELJAMILI, M ELHATTAOUI MOROCCO Background: Cardiac arrhythmias are frequently observed in patients with endstage renal disease on hemodialysis (ESRD), The most frequent cause of cardiac arrythmias death is ventricular arrhythmia which usually precedes by premature ventricular contraction (PVC) and are associated with high morbidity and mortality. The purpose of our study is to determine if hemodialysis is responsible for causing these potentially fatal cardiac arrhythmias, or is it the progression of chronic kidney disease itself with its complications on the cardiovascular system that is responsible for it. 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