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CARDIOVASCULAR JOURNAL OF AFRICA • Volume 29, No 1, January/February 2018

AFRICA

5

contribution of Gershlick

et al

.,

1

which may be recommended for

the formulation of solutions to enable prevention or reduction in

STEMI-related mortality and morbidity in South Africa.

References

1.

Gershlick AH, Banning AP, Myat A, Verheugt FW, Gersh BJ.

ST-segment elevation myocardial infarction 1: reperfusion therapy for

STEMI: is there still a role for thrombolysis in the era of primary percu-

taneous coronary intervention?

Lancet

2013;

382

(9892): 624–632. DOI:

10.1016/S0140-6736(13)61454-3.

2.

Ibanez B, James S, Agewall S,

et al

. 2017 ESC guidelines for the

management of acute myocardial infarction in patients presenting

with ST-segment elevation: the task force for the management of acute

myocardial infarction in patients presenting with ST-segment elevation

of the European Society of Cardiology (ESC).

Eur Heart J

2018;

39

:

119–177.

https://doi.org/10.1093/eurheartj/ehx393.

3.

Mortality and causes of death in South Africa, 2015: Findings from

death notification. Statistics South Africa. Statistical release P0309.3.

http://www.statssa.gov.za/publications/P03093/P030932015.pdf

4.

Mid-year population estimates 2015. Statistics South Africa. Statistical

release P0302.

https://www.statssa.gov.za/publications/P0302/

P03022015.pdf

5.

Use of health facilities and levels of selected health conditions in South

Africa: Findings from the General Household Survey, 2011. Statistics

South Africa. Report no. 03-00-05 (2011).

http://www.statssa.gov.za/

publications/Report-03-00-05/Report-03-00-052011.pdf

6.

Stassen W, Wallis LA, Lambert C, Castren M, Kurland L. Percutaenous

coronary intervention still not accessible for many South Africans.

Afr J Emerg Med

2017;

7

: 105–107.

http://dx.doi.org/10.1016/j.

afjem.2017.04.009.

7.

Baliga RR, Bahl VK, Alexander T, Mullasari A, Manga P, Dec GW,

Narula J. Management of STEMI in low- and middle-income countries.

Glob Heart

2014;

9

(4): 469–510. doi: 10.1016/j.gheart.2014.11.001.

Confidence Through Clinical and Real World Experience

1-3

Millions of Patients Treated Worldwide Across Multiple Indications

4

#1 Scripted Non-VKA Oral Anticoagulant by Cardiologists*

*Impact RX Data 2016

NOAC: Non Vitamin K Oral Anticoagulant

REFERENCES:

1. Patel M.R., Mahaffey K.W., Garg J.

et al

. Rivaroxaban versus warfarin in non-valvular atrial fi brillation.

N Engl J Med

. 2011;365(10):883–91. 2. Tamayo S., Peacock W.F., Patel M.R.,

et al

. Characterizing

major bleeding in patients with nonvalvular atrial fi brillation: A pharmacovigilance study of 27 467 patients taking rivaroxaban.

Clin Cardiol

. 2015;38(2):63–8. 3. Camm A.J., Amarenco P., Haas S.

et al

. XANTUS: A

Real-World, Prospective, Observational Study. 4. Calculation based on IMS Health MIDAS, Database: Monthly Sales January 2017.

S4 Xarelto 15: Each film-coated tablet contains rivaroxaban 15 mg. Reg. No: 46/8.2/0111; Namibia NS2 : 12/8.2/0006; S2 Botswana: BOT1302296; Zimbabwe: PP10 Reg. 2017/10.2/5363

S4 Xarelto 20: Each film-coated tablet contains rivaroxaban 20 mg. Reg. No: 46/8.2/0112;Namibia NS2 : 12/8.2/0007; S2 Botswana: BOT1302297; Zimbabwe: PP10 Reg. 2017/10.2/5364

PHARMACOLOGICAL CLASSIFICATION:

A.8.2 Anticoagulants.

INDICATIONS:

(1) Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (SPAF); (2) Treatment of deep vein thrombosis

(DVT) and for the prevention of recurrent deep vein thrombosis (DVT) and pulmonary embolism (PE); (3) Treatment of pulmonary embolism (PE) and for the prevention of recurrent pulmonary embolism (PE) and deep

vein thrombosis (DVT). For full prescribing information, refer to the package insert approved by the Medicines Regulatory Authority (MCC).

HCR:

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© Bayer June 2017