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CARDIOVASCULAR JOURNAL OF AFRICA • Volume 31, No 3, May/June 2020
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AFRICA
our study also has limitations, including: lack of prospective
registration, small study size, unconventional randomisation
approach and open study design. However, the primary purpose
of our study was to demonstrate feasibility, which we were
able to accomplish. Furthermore, our co-primary outcome
assessment was objectively measured and defined and therefore
less susceptible to detection bias.
We aim to use these data to catalyse a large-scale, multi-
level interventional study in Nigeria that tests the effects of
community health worker support and home blood pressure
monitoring together, rather than separately, to improve
hypertension treatment and control rates and reduce the burden
of hypertension-related diseases in Nigeria.
Study medications were donated by Micro nova Pharmaceuticals Nigeria Ind,
Limited as part of their educational grant.
References
1.
GBD 2013 Mortality and Causes of Death Collaborators. Global,
regional, and national age–sex specific all-cause and cause-specific
mortality for 240 causes of death, 1990–2013: a systematic analysis for
the Global Burden of Disease Study 2013.
Lancet
2014;
385
: 117–171.
2.
Adeloye D, Basquill C, Aderemi AV, Thompson JY, Obi FA. An esti-
mate of the prevalence of hypertension in Nigeria: a systematic review
and meta-analysis.
J Hypertens
2015;
33
: 230–242.
3.
Salako BL, Ogah OS, Adebiyi AA, Ojji DB, Ipadeola A, Nwafor CE.
Blood pressure control and left ventricular hypertrophy in hypertensive
Nigerians.
Ann Afr Med
2009;
8
(3): 156–162.
4.
Ojji DB, Alfa J, Ajayi SO, Mamven MH, Falase AO. Pattern of heart
failure in Abuja, Nigeria: an echocardiographic study.
Cardiovasc J Afr
2009;
20
: 349–352.
5.
Ogah OS, Stewart S, Falase AO, Akinyemi JO, Adegbite GD, Alabi AA,
et al.
Contemporary profile of acute heart failure in southern Nigeria.
Data from the Abeokuta Heart Failure Clinical Registry.
JACC Heart
Failure
2014;
2
: 250–259.
6.
Ulasi II, Ijoma CK. The enormity of chronic kidney disease in Nigeria:
the situation in a teaching hospital in South-East Nigeria.
J Trop Med
2010; 501957.
7.
Arogundade FA, Sanusi AA, Hassan MO, Akinsola A. The pattern,
clinical characteristics and outcomes of ESRD in Ile-Ife, Nigeria: is
there a change in trend?
Afr Health Sci
2011;
11
: 594–601.
8.
Ogun SA, Ojini FI, Ogungbo B, Kolapo KO, Danesi MA. Stroke in
South West Nigeria: a 10-year review.
Stroke
2005;
36
:1120–1122.
9.
Wahab KW. The burden of stroke in Nigeria.
Int J Stroke
2008;
3
:
290–292.
10. Svetkey LP, Pollak KI, Yancy WS, Dolor RJ, Batch BC, Samsa G,
et al
. Hypertension improvement project: randomized trial of qual-
ity improvement for physicians and lifestyle modification for patients.
Hypertension
2009;
54
: 1226.
11. Tucker KL, Sheppard JP, Stevens R, Bosworth HB, Bove A, Bray EP,
et al.
Self-monitoring of blood pressure in hypertension: A systematic
review and individual patient data meta-analysis.
PLoS Med
2017;
14
(9):
e1002389.