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CARDIOVASCULAR JOURNAL OF AFRICA • Volume 29, No 2, March/April 2018

AFRICA

117

Diagnostic facilities and challenges

Electrocardiography (ECG):

as shown in Table 2, ECG was

widely available in all African countries, although mainly in

secondary and tertiary health facilities. Signal-averaged ECG

(SA-ECG), which detects arrhythmogenic late potentials for the

diagnosis of arrhythmogenic right ventricular cardiomyopathy/

dysplasia (ARVC/D) was available only in South Africa and in

Maghreb.

Ambulatory ECG monitoring (24-hour Holter-ECG) and

exercise treadmill testing were not routinely performed in many

countries. These tests were available in only 76 and 61% of

the countries, respectively, and they were very expensive. For

instance, in Cameroon, they cost approximately US$180, about

2.7-fold higher than the minimum monthly wage.

Other diagnostic techniques: echocardiography was the most

commonly used imaging technique to rule out or confirm

structural heart diseases. Although widely available in Africa

(Table 2), its use was limited to tertiary centres in larger cities.

Tilt-testing

to rule out vaso-vagal syncope was available in only

six (18.2%) countries (Table 2).

Electrophysiological procedures (EP) for the diagnosis of

paroxysmal advanced heart blocks or tachyarrhythmias were

routinely performed only in countries from North Africa, Kenya,

Senegal and SouthAfrica. Other SSAcountries with implantation

activity were able to supply pacemaker implantations to only

patients with overt conduction system disturbances, excluding

the remaining population with unexplained syncope. A catheter

laboratory was not available in 19 (57.6%) countries (Fig. 1).

Drug challenge aims to unmask silent phenotypes of

inheritable arrhythmogenic diseases such as Brugada syndrome.

However, this test was largely unavailable in many countries of

SSA, with anecdotal reports on ajmaline or flecanide use in some

countries (Fig. 4).

Treatments

Anti-arrhythmia drugs: as shown in the Table 3, digoxin and

amiodarone were the most commonly usedmedications. Vaughan

William’s class I anti-arrhythmic drugs were in short supply,

apart from flecainide, which was present in about 50% of the

Fig. 1.

Availability of various cardiac arrhythmia services across the African continent. PMK = pacemaker; ICD = implantable cardio-

verter defibrillator; CRT = cardiac resynchronisation therapy. Ablation includes radiofrequency ablation for atrial flutter and

junctional tachycardia (simple ablation) as well as catherter ablation for atrial fibrillation (complex ablation).