Background Image
Table of Contents Table of Contents
Previous Page  35 / 67 Next Page
Information
Show Menu
Previous Page 35 / 67 Next Page
Page Background

CARDIOVASCULAR JOURNAL OF AFRICA • Vol 24, No 2, March 2013

AFRICA

33

isolated aortic valvular lesion is not considered a definite RHD

case. That is why there was no patient with isolated aortic vulvlar

lesion seen in our study.

Conclusion

Rheumatic heart disease continues to be a major health problem

in cardiac patients presenting to Mulago Hospital. It accounts for

a large percentage of cardiovascular disease-related admissions

and is an important indication for cardiac surgery in Uganda.

Patients with newly diagnosed RHD in Mulago present with

an advanced disease pattern of clinically severe symptoms

associated with poor quality of life, moderate-to-severe form

of valvular lesions and high frequency of complications. All

these reflect a high burden of RHD in this country, a delayed

diagnosis and delayed seeking of medical services. Young

females accounted for the majority of the study population. The

majority of the newly diagnosed RHD patients required valvular

heart surgery, which is not yet available locally.

This study was supported by a postgraduate research grant from the Uganda

National Council for Science and Technology under the Millennium Science

Initiative and the Uganda Heart Institute. The expert technical assistance of

Sebatta Elias is gratefully acknowledged. Ms Mwesige Beatrice and Gladys

Kahima of the Echocardiography laboratory are also acknowledged.

References

1.

Carapetis JR, Steer AC, Mulholland EK, Weber M. The global burden

of group A streptococcal diseases.

Lancet Infect Dis

2005;

5

: 685–694.

2.

Nishimura RA, Carabello BA, Faxon DP, Freed MD, Lytle BW, O’Gara

PT,

et al

. ACC/AHA 2008 guidelines for the management of patients

with valvular heart disease.

J Am Coll Cardiol

2008;

52

(8): 676–685.

3.

Control of RF and RHD. Geneva, WHO, 1988 (WHO Technical Report

Series, No. 764).

4.

World Heart Federation: RHD in Africa.

www.worldheart.org

.

5.

Diagnosis and management of ARF and RHD, 2007 World Heart

Federation, updated Oct. 2008.

6.

Anonymous. Rheumatic fever and rheumatic heart disease.

World

Health Organ Tech Rep Ser

2004;

923

: 1–122.

7.

WHO. Rheumatic fever and rheumatic heart disease: report of a WHO

expert consultation. Geneva: World Health Organization, 2004.

8.

Li SQ, Guthridge S, d’Espaignet EBP. From infancy to young adult-

hood: health status in the Northern Territory, 2006: Department of

Health and Community Services; 2007.

9.

National Heart Foundation of Australia (NHFA) and the Cardiac

Society of Australia and New Zealand (CSANZ). Diagnosis and

management of acute rheumatic fever and rheumatic heart disease in

Australia – an evidence-based review, 2006.

10. Kayima J, Mungoma M, Mondo C, Freers J. The changing pattern of

cardiac disease in Africa: The Uganda experience.

Cardiovasc J Afr

2011;

22

(3): S9.

11. Carapetis JP, Cherian T. Standardization of epidemiologic protocols

for surveillance of post-streptococcal sequelae: acute rheumatic fever,

rheumatic heart disease and acute post-streptococcal glomerulonephri-

tis: National Institutes of Health and World Health Organization, 2006.

12. Picard MH, Adams D, Bierig M, Dent JM, Douglas PS, Gillam LD,

et

al.

American Society of Echocardiography recommendations for qual-

ity echocardiography laboratory operations.

J Am Soc Echocardiogr

2011;

24

(1):1–10.

13. Recommendations for chamber quantification: a report from the

American Society of Echocardiography’s Guidelines and Standards

Committee and the Chamber Quantification Writing Group

. J Am Soc

Echocardiogr

2005;

18

: 1440–1463.

14. Sliwa K, Carrington M, Mayosi B, Zigiriadis E, Mvungi R, Stewart

S. Incidence and characteristics of newly diagnosed rheumatic heart

disease in urban Africa adults: insights from the Heart of Soweto Study.

Eur Heart J

2010;

31

: 719–727.

15. Aurakzai H, Hameed S, Shahbaz A, Gohar S, Qureshi M, Khan H,

et

al

. ECHO profile of RHD at a tertiary cardiac centre.

J Ayub Med Coll

Abbottabad

2009;

21

(3): 122–126.

16. Murray CJ, Lopez AD (eds).

Global Health Statistics

. Cambridge:

Harvard University Press, 1996: 643–645.

17. Tantchou Tchoumi JC, Butera G. Rheumatic valvulopathies occur-

rence, pattern and follow up in rural area: the experience of Shisong

Hospital, Cameroon.

Bull Soc Pathol Exot

2009;

102

(3): 155–158.

18. Yuko-Jowi C, Bakari M. Echocardiographic pattern of juvenile rheu-

matic heart disease at the Kenyatta National Hospital, Nairobi.

East Afr

Med J

2005;

82

(10): 514–519.

19. Rowe JC, Bland EF, Sprague HB, White PD. The course of mitral

stenosis without surgery: 10 and 21-year perspectives

. Ann Int M

ed

1960;

52

: 741–749.

20. Saleb HK. Pattern of rheumatic heart disease in SouthernYemen.

Saudi

Med J

2007;

28

(1): 108–113.

21. Beaton A, Okello E, Batambuze W, Lwabi P, Mondo C, Sable C.

Rhuematic heart disease in Ugandan primary school children: Applying

the 2006 WHO/NIH consensus statement on echocardiography guide-

lines.

Cardiovasc J Afr

2011;

22

(3): S3.

22. Steer AC, Kado J, Jenney AW, Batzloff M, Waqatakirewa L, Mulholland

KE, Carapetis JR. Acute rheumatic fever and rheumatic heart disease

in Fiji: Prospective surveillance, 2005–2007

. Med J Afr

2009;

190

(3):

133–135.

23. Berger M, Haimowitz A, van Tosh A, Berdoff RL, Godberg E.

Quantitative assessment of pulmonary hypertention in patients with

tricuspid regurgitation using continous wave Doppler ultrasound.

J Am

Coll Cardiol

1985;

6

: 359–365.