Cardiovascular Journal of Africa: Vol 26 No 4 (July/August 2015)

CARDIOVASCULAR JOURNAL OF AFRICA • Volume 26, No 4, July/August 2015

AFRICA

163

counts, and N:L ratios. When compared with pre-operative

values, the results indicated that CPB caused significantly

decreased lymphocyte counts and increased N:L ratios on

the first postoperative day. On the other hand, on the fifth

postoperative day, total leukocyte and neutrophil counts were

significantly increased in the CPB group.

From these results, the influence of CPB versus OPCAB on

changes in leukocyte counts after surgery was shown to be more

prominent in the early stages after surgery. In the CPB group,

the increase in N:L ratio was more pronounced than that in

the OPCAB group only on the first day after surgery. Although

we showed that pre-operative values were significantly different

from those measured on the first day after surgery, the effect

was transient. However, as the magnitude of the response of

peripheral leukocytes has been suggested to be related to cardiac

surgery, it could be postulated that this transient effect may be

greater when the patient undergoes CABG with CPB.

A limitation of this study was that C-reactive protein tests,

being an indicator of inflammation, were not done.

Conclusion

Our data showed that OPCAB compared with CPB could

favourably modify leukocyte count changes, including N:L ratio

in the peripheral blood stream during the postoperative period

of CABG surgery.

The authors are grateful for the cooperation of people who collected and

managed the database of our institution.

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