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ISSN 1995-1892 (print)

ISSN 1680-0745 (online)

Cardiovascular Journal of Africa

www.cvja.co.za

CONTENTS

INDEXED AT SCISEARCH (SCI), PUBMED, PUBMED CENTRAL AND SABINET

Vol 27, No 2, MARCH/APRIL 2016

Editors

Editor-in-Chief

(South Africa)

Prof Pat Commerford

Guest Editor

prof karen sliwa

Assistant Editor

Prof JAMES KER (JUN)

Regional Editor

DR A Dzudie

Regional Editor (Kenya)

Dr F Bukachi

Regional Editor (South Africa)

PROF R DELPORT

Editorial Board

prof PA Brink

Experimental & Laboratory

Cardiology

PROF R DELPORT

Chemical Pathology

PROF MR ESSOP

Haemodynamics, Heart Failure

& Valvular Heart Disease

DR OB FAMILONI

Clinical Cardiology

DR V GRIGOROV

Invasive Cardiology & Heart

Failure

PROF J KER (SEN)

Hypertension, Cardiomyopathy,

Cardiovascular Physiology

DR J LAWRENSON

Paediatric Heart Disease

PROF A LOCHNER

Biochemistry/Laboratory

Science

PROF BM MAYOSI

Chronic Rheumatic Heart

Disease

DR MT MPE

Cardiomyopathy

PROF DP NAIDOO

Echocardiography

PROF B RAYNER

Hypertension/Society

PROF MM SATHEKGE

Nuclear Medicine/Society

PROF YK SEEDAT

Diabetes & Hypertension

PROF H DU T THERON

Invasive Cardiology

International

Advisory Board

PROF DAVID CELEMAJER

Australia (Clinical Cardiology)

PROF KEITH COPELIN FERDINAND

USA (General Cardiology)

DR SAMUEL KINGUE

Cameroon (General Cardiology)

DR GEORGE A MENSAH

USA (General Cardiology)

PROF WILLIAM NELSON

USA (Electrocardiology)

DR ULRICH VON OPPEL

Wales (Cardiovascular Surgery)

PROF PETER SCHWARTZ

Italy (Dysrhythmias)

PROF ERNST VON SCHWARZ

USA (Interventional Cardiology)

SUBJECT Editors

Nuclear Medicine and Imaging

DR MM SATHEKGE

Heart Failure

Dr g visagie

Paediatric

dr s brown

Paediatric Surgery

Dr Darshan Reddy

Renal Hypertension

dr brian rayner

Surgical

dr f aziz

Adult Surgery

dr j rossouw

Epidemiology and Preventionist

dr ap kengne

Pregnancy-associated Heart

Disease

Prof K Sliwa-hahnle

Editorial

59 Cardiovascular disease in pregnancy: the South African perspective

J Anthony • A Sarkin • K Sliwa

Cardiovascular Topics

60 The importance of cardiovascular pathology contributing to maternal death:

Confidential Enquiry into Maternal Deaths in South Africa, 2011–2013

P Soma-Pillay • J Seabe • K Sliwa

66 Electrocardiographic predictors of peripartum cardiomyopathy

KM Karaye • K Lindmark • MY Henein

Review Articles

71 Pre-eclampsia: its pathogenesis and pathophysiolgy

P Gathiram • J Moodley

79 Pre-conception counselling for key cardiovascular conditions in Africa: optimising

pregnancy outcomes

L Zühlke • L Acquah

84 Medical disease as a cause of maternal mortality: the pre-imminence of cardiovascular

pathology

AO Mocumbi • K Sliwa • P Soma-Pillay

89 Physiological changes in pregnancy

P Soma-Pillay • C Nelson-Piercy • H Tolppanen • A Mebazaa

95 Diagnosing cardiac disease during pregnancy: imaging modalities

NAB Ntusi • P Samuels • S Moosa • AO Mocumbi

104 Hypertensive disorders of pregnancy: what the physician needs to know

J Anthony • A Damasceno • D Ojjii