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CARDIOVASCULAR JOURNAL OF AFRICA • Volume 28, No 3, May/June 2017

140

AFRICA

strategies and action plans to reduce exposure to patients and

staff should be followed.

11

Institutional insensitivity should also

be addressed and the proper fundamental principles of radiation

protection should be rigidly applied.

The profession shouldbe concernedabout how interventionists

and young cardiologists with long careers ahead of them can

avoid the ravages of exposure to ionising radiation. Over a

lifetime, how much radiation exposure is acceptable and how

much are we at risk of the complications of prolonged and

recurrent exposure? The time to act is now.

References

1.

IRPA guiding principles for establishing a radiation protection

culture. URL: http://

http://www.irpa.net/members/IRPA-Guiding%20

Principles%20on%20RP%20Culture%20-2014%20.pdf.

2.

Vano E, Kleiman NJ, Duran A, Romano-Miller M, Rehani MM.

Radiation-associated lens opacities in catheterization personnel: results

of a survey and direct assessments.

J Vasc Interv Radiol

2013;

24

:

197–204.

3.

Roguin A, Goldstein J, Bar O. Brain tumours among interventional

cardiologists: a cause for alarm? Report of four new cases from two

cities and a review of the literature.

EuroIntervention

2012;

7

: 1081–1086.

4.

Roguin A, Goldstein J, Bar O. Brain malignancies and ionising radia-

tion: more cases reported.

EuroIntervention

2012;

8

: 169–170.

5.

Roguin A, Goldstein J, Bar O, Goldstein JA. Brain and neck tumors

among physicians performing interventional procedures.

Am J Cardiol

2013;

111

: 1368–1372.

6.

Picano E, Vano E, Domenici L,

et al

. Cancer and non-cancer brain

and eye effects of chronic low-dose ionizing radiation exposure.

BMC

Cancer

2012;

12

: 157.

7.

Marazziti D, Baroni S, Catena-Dell’Osso M,

et al

. Cognitive, psycho-

logical and psychiatric effects of ionizing radiation exposure.

Curr Med

Chem

2012;

19

: 1864–1869.

8.

Kumar G, Rab ST. Radiation safety for the interventional cardi-

ologist – a practical approach to protecting ourselves from the dangers

of ionizing radiation.

http://www.acc.org/latest-in-cardiology/arti-

cles/2015/12/31/10/12/radiation-safety-for-the-interventional-cardiolo-

gist.

9.

Leyton F, Canevero L, Dourado A,

et al.

Radiation risks and the

importance of radiological protection in interventional cardiology: a

systematic review.

Rev Bras Cardiol Invasiva

2014;

22

: 87–98.

10. Rose A, Ray W. Perception of radiation safety training among interven-

tionalists in South Africa.

Cardiovasc J Afr

2017; 196–200.

11. Fazel R, Gerber TC, Balter S,

et al

. Approaches to enhancing radia-

tion safety in cardiovascular imaging. A scientific statement from the

American Heart Association. Intervention.

Circulation

2014;

130

:

1730–1734.

Confidence Through Clinical

and Real World Experience

1-3

Millions of Patients Treated Across Multiple Indications

4

#1 NOAC prescribed by Cardiologists

*

*Impact RX Data Oct - Dec 2015

NOAC: Non Vitamin K Oral Anticoagulant

REFERENCES: 1.

Patel M.R., Mahaffey K.W., Garg J.

et al.

Rivaroxaban versus warfarin in non-valvular atrial fi brillation.

N Engl J Med

. 2011;365(10):883–91.

2.

Tamayo S., Peacock W.F., Patel M.R.,

et al.

Characterizing major bleeding in patients

with nonvalvular atrial fi brillation: A pharmacovigilance study of 27 467 patients taking rivaroxaban.

Clin Cardiol

. 2015;38(2):63–8.

3.

Camm A.J., Amarenco P., Haas S.

et al.

XANTUS: A Real-World, Prospective, Observational Study.

4.

Calculation

based on IMS Health MIDAS, Database: Monthly Sales December 2015.

S4 XARELTO

®

15: Each film-coated tablet contains rivaroxaban 15 mg. Reg. No: 46/8.2/0111; Namibia S2 : 12/8.2/0006; Botswana S2 : BOT1302296

S4 XARELTO

®

20: Each film-coated tablet contains rivaroxaban 20 mg. Reg. No: 46/8.2/0112; Namibia S2 : 12/8.2/0007; Botswana S2 : BOT1302297

PHARMACOLOGICAL CLASSIFICATION:

A.8.2 Anticoagulants.

INDICATIONS:

(1) Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (SPAF); (2) Treatment of deep vein thrombosis (DVT) and for the prevention

of recurrent deep vein thrombosis (DVT) and pulmonary embolism (PE); (3) Treatment of pulmonary embolism (PE) and for the prevention of recurrent pulmonary embolism (PE) and deep vein thrombosis (DVT).

HCR:

Bayer (Pty) Ltd, Co. Reg. No.:

1968/011192/07, 27 Wrench Road, Isando, 1609. Tel: +27 (0) 11 921 5044 Fax: +27 (0) 11 921 5041. For full prescribing information, refer to the package insert approved by the Medicines Regulatory Authority (MCC).

L.ZA.MKT.GM.01.2016.1265

© Bayer January 2016