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CARDIOVASCULAR JOURNAL OF AFRICA • Volume 30, No 5, September/October 2019

AFRICA

257

41

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Healthy food more important than type of diet to cut heart disease risk

Everyone knows that achieving or maintaining a healthy body

weight is one key to preventing cardiovascular disease. But

even experts don’t agree on the best way to achieve that goal,

with some recommending eliminating carbohydrates and

others emphasising reducing fats to lose weight. Few studies

have investigated the effects of these specific macronutrients

on cardiovascular health.

In a study, researchers at Beth Israel Deaconess Medical

Centre (BIDMC) examined the effects of three healthy

diets emphasising different macronutrients – carbohydrates,

proteins, or unsaturated fats – on a biomarker that directly

reflects heart injury. Using highly specific tests, the team

found that all three diets reduced heart cell damage and

inflammation, consistent with improved heart health.

‘It’s possible that macronutrients matter less than simply

eating healthy foods,’ said corresponding author Dr Stephen

Juraschek, assistant professor of medicine at BIDMC and

Harvard Medical School. ‘Our findings support flexibility

in food selection for people attempting to eat a healthier

diet and should make it easier. With the average American

eating fewer than two servings of fruit and vegetables a day,

the typical American diet is quite different from any of these

diets, which all included at least four to six servings of fruits

and vegetables a day.’

Juraschek and colleagues analysed stored blood samples

from 150 participants of the Optimal Macro-Nutrient

Intake Trial to Prevent Heart Disease (OmniHeart) trial, a

two-centre, in-patient feeding study conducted in Boston

and Baltimore between April 2003 and June 2005. The

average age among the study participants was 53.6 years,

and 55% were African American and 45% were women.

The participants, all of whom had elevated blood pressure,

but were not yet taking medications to control hypertension

or cholesterol, were fed each of three diets – emphasising

carbohydrates, protein, or unsaturated fat – for six weeks

with feeding periods separated by a wash-out period.

The diets were: a carbohydrate-rich diet similar to the

well-known DASH diet, with sugars, grains and starches

accounting for more than half of its calories; a protein-rich

diet with 10% of calories from carbohydrates replaced by

protein; and an unsaturated fat-rich diet with 10% of calories

from carbohydrates replaced by the healthy fats found in

avocados, fish and nuts. All three diets were low in unhealthy

saturated fat, cholesterol and sodium, while providing other

nutrients at recommended dietary levels.

The research team looked at the effects of each diet on

biomarkers measured at the end of each dietary period

compared to baseline and compared between diets.

All three healthy diets reduced heart injury and

inflammation and acted quickly within a six-week period.

However, changing the macronutrients of the diet did not

provide extra benefits. This is important for two reasons.

First, the effects of diet on heart injury are rapid and cardiac

injury can be reduced soon after adopting a healthy diet.

Second, it is not the type of diet that matters for cardiac

injury (high or low fat, high or low carb), but rather the

overall healthfulness of the diet.

‘There are multiple debates about dietary carbs and fat,

but the message from our data is clear: eating a balanced diet

rich in fruits and vegetables, lean meats, and high in fibre that

is restricted in red meats, sugary beverages, and sweets, will

not only improve cardiovascular risk factors, but also reduce

direct injury to the heart,’ said Juraschek. ‘Hopefully, these

findings will resonate with adults as they shop in grocery

stores and with health practitioners providing counsel in

clinics throughout the country.’

Source:

Medical Brief 2019