CARDIOVASCULAR JOURNAL OF AFRICA • Volume 31, No 4, July/August 2020
AFRICA
195
30. Nyesigire Ruhinda E, Bajunirwe F, Kiwanuka J. Anaemia in
HIV-infected children: severity, types and effect on response to ART.
BMC Pediatr
2012;
12
: 170.
31. Assefa M, Abegaz WE, Shewamare A, Medhin G, Belay M. Prevalence
and correlates of anemia among HIV infected patients on highly active
anti-retroviral therapy at Zewditu Memorial Hospital, Ethiopia.
BMC
Hematol
2015;
15
: 6.
32. Cerrato E, D’Ascenzo F, Biondi-Zoccai G, Calcagno A, Frea S, Grosso
Marra W,
et al
. Cardiac dysfunction in pauci symptomatic human
immunodeficiency virus patients: a meta-analysis in the highly active
antiretroviral therapy era.
Eur Heart J
2013;
34
(19): 1432–1436.
33. Gundersen GH, Norekval TM, Haug HH, Skjetne K, Kleinau JO,
Graven T,
et al
. Adding point of care ultrasound to assess volume status
in heart failure patients in a nurse-led outpatient clinic. A randomised
study.
Heart
2016;
102
(1): 29–34.
34. Colquhoun SM, Carapetis JR, Kado JH, Reeves BM, Remenyi B, May
W,
et al
. Pilot study of nurse-led rheumatic heart disease echocardiog-
raphy screening in Fiji – a novel approach in a resource-poor setting.
Cardiol Young
2013;
23
(4): 546–552.
35. Diallo I, Meda N, Ouédraogo S, Poda A, Hema A, Sagna Y,
et al
.
Profiles of elderly people infected with HIV and response to antiretrovi-
ral treatment in Burkina Faso: a retrospective cohort study.
J Int Assoc
Provid AIDS Care
2017;
16
(4): 405–411.
36. Dillon DG, Gurdasani D, Riha J, Ekoru K, Asiki G, Mayanja BN,
et al
.; African Partnership for Chronic Disease Research (APCDR).
Association of HIV and ART with cardiometabolic traits in sub-
Saharan Africa: a systematic review and meta-analysis
. Int J Epidemiol
2013;
42
(6): 1754–1771.
37. Angkurawaranon C, Nitsch D, Larke N, Rehman AM, Smeeth L, Addo
J. Ecological study of HIV infection and hypertension in sub-Saharan
Africa: is there a double burden of disease?
PLoS One
2016;
11
(11):
e0166375.
Trust the
!
Original
S3 ISMO-20 R/7.1.4/136. Isosorbide-5-mononitrate 20 mg/tablet.
For full prescribing information, please refer to package insert.
Pharmaco Distribution (Pty) Ltd. 3 Sandown Valley Crescent, South Tower, 1st Floor, Sandton, 2196; PO Box 786522, Sandton, 2146, South Africa. Tel: + 27 11 784 0077.
Website:
www.pharmaco.co.za1
Long-term prophylaxis and management of
Angina Pectoris
2,3
=
100%
bioavailability
No first-pass metabolism
4
Twice daily
dosage regimen shown
to avoid withdrawal and tolerance
References: 1.
South African approved ISMO package insert.
2.
Ismo 20 Product Monograph (2015).
3.
Abshagen, U., 1992. Pharmacokinetics of isosorbide mononitrate.
The American Journal of Cardiology,
[online] 70(17), pp.G61-G66.
4.
Thadani U, Maranda CR, Amsterdam E, et al. Lack of Pharmacological Tolerance and Rebound
Angina Pectoris during Twice-daily Therapy with Isosorbide-5-Mononitrate.
Annals of Internal Medicine.
1994; 120:353-359. IS_0120.