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CARDIOVASCULAR JOURNAL OF AFRICA • Volume 27, No 4, July/August 2016

e16

AFRICA

structural and functional abnormalities, such as ventricular

dysfunction, valvular pathology, mural thrombosis, and atrial

septal defect or patent foramen ovale. The pocket is made deep

and lateral to allow the pump to be fixed below the diaphragm.

The outflow cannula is placed to the right of the sternal midline

with enough graft length to avoid any compression of the RV.

The management of bleeding is indivisibly linked to the risk

of thromboembolic events, and anticoagulation and antiplatelet

therapies seem to be the only methods for carefully managing

complication and individual risks. Further understanding of the

mechanisms underlying bleeding and novel strategies, such as

new anticoagulant drugs, are expected to play crucial roles in the

long-term management of cf-LVAD therapy.

1

Cardiac arrhythmia, such as ventricular arrhythmia, is also

a common issue in the early and late periods after cf-LVAD

implantation. Although such arrhythmias may not be lethal in

the presence of cf-LVAD, it could put patients at a risk of RVF.

1

Anti-arrhythmic medication, catheter ablation, intra-operative

cryoablation, and implantable cardioverter–defibrillator may be

employed to minimise the risk of recurrent arrhythmias.

1

End-organ function was restored one month after the

initiation of support.

1

These improvements persisted throughout

the support period; for example, the LV diastolic dimension

significantly decreased and the TR ratio reduced from 45 to 22%

at one month, except for the creatinine level.

1

Conclusion

The implantation of cf-LVAD, either as BTT or DT, remains a

critical treatment option for selected patients with end-stage HF.

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