

CARDIOVASCULAR JOURNAL OF AFRICA • Volume 28, No 3, May/June 2017
AFRICA
149
Nigeria (28.4%), while overall obesity was highest in Cameroon
(53.6%) and lowest in Madagascar (10.0%) (
p
<
0.001). Details of
the cardiometabolic risk factors across the countries are shown
in Table 2.
When participants were assessed according to their hyperten-
sion status (Table 3), diabetes mellitus and hypercholesterolaemia
were more common among participants with hypertension (17.7
vs 10.0%;
p
=
0.010 and 25.8 vs 18.0%;
p
=
0.008, respectively)
than in normotensives. With regard to WC, 73.4% of women
had a WC
>
88 cm, most (79.4%) of whom were hypertensive,
opposed to 67.7% who were non-hypertensive (
p
=
0.004).
This difference was not statistically significant among the men.
Overall, participants with hypertension were more likely to be
overweight (33.2 vs 30.5%) and obese (42.5 vs 16.8%) (
p
<
0.001),
but reported lower smoking rates (15.0 vs 24.1%;
p
=
0.002).
Hypertensionand smokingweremore prevalent inparticipants
with diabetes (83.3 vs 71.9%;
p
=
0.010 and 19.7 vs 17.9%;
p
=
0.019, respectively). The distribution of other risk factors,
Table 1. General characteristics and overall profile of study population
Cameroon (
n
=
154) 17.9% Nigeria (
n
=
211) 25.9%
DRC (
n
=
239) 28.1% Madagascar (
n
=
240) 28.1%
Total (
n
=
844)
Variables
Male
(
n
=
54)
Female
(
n
=
100)
p
-value
Male
(
n
=
87)
Female
(
n
=
124)
p
-value
Male
(
n
=
116)
Female
(
n
=
123)
p
-value
Male
(
n
=
103)
Female
(
n
=
137)
p
-value
Male
(
n
=
360)
(42.6%)
Female
(
n
=
484)
(57.4%)
Total
(
n
=
844)
p
-value
Age (years)
51.5
±
9.7 56.4
±
11.2 0.009 50.3
±
13.2 48.8
±
11.3 0.369 56.7
±
11.2 55.7
±
12.9 0.532 51.4
±
10.0 49.5
±
9.9 0.147 52.8
±
11.5 52.3
±
11.8 52.6
±
11.7 0.512
BMI (kg/m
2
)
29.7
±
3.8 31.1
±
6.7 0.184 28.6
±
6.1 31.2
±
6.4 0.003 27.7
±
6.8 30.4
±
6.2 0.002 25.1
±
4.0 25.0
±
3.9 0.930 27.5
±
5.8 29.3
±
6.4 28.5
±
6.1 0.000
BMI category,
n
(%)
Normal
06 (11.1)
22 (22.0)
29 (33.4)
21 (16.8)
39 (33.6)
25 (20.4)
53 (51.4)
69 (50.4)
127 (35.3) 137 (28.3) 264 (31.3)
Overweight
22 (40.7)
23 (23.0) 0.005 27 (31.0)
32 (25.8) 0.007 38 (32.8)
37 (30.1) 0.005 40 (38.8)
54 (39.4) 0.983 127 (35.3) 146 (30.2) 273 (32.3) 0.000
Obese
26 (48.2)
43 (43.0)
28 (32.2)
59 (47.7)
38 (32.8)
50 (40.6)
10 (9.7)
14 (10.2)
102 (28.3) 166 (34.3) 268 (31.8)
Morbidly obese 00 (0.0)
12 (12.0)
03 (3.4)
12 (9.7)
01 (0.8)
11 (8.9)
00 (0.0)
00 (0.0)
04(1.1)
35 (7.2)
39 (4.6)
WC (cm)
101.2
±
12.8 102.7
±
16.1 0.559 91.2
±
11.5 97.4
±
15.4 0.001 97.7
±
17.9 99.9
±
14.5 0.279 91.2
±
11.2 88.4
±
10.5 0.049 94.8
±
14.5 96.6
±
15.1 95.8
±
14.8 0.071
HC (cm)
104.5
±
12.3 109.4
±
19.8 0.101 96.8
±
12.6 106.2
±
18.2 0.000 101.1
±
10.0 110.6
±
14.6 0.000 97.8
±
7.5 99.4
±
9.1 0.155 99.6
±
10.8 106.1
±
16.2 103.2
±
14.5 0.000
SBP (mmHg)
168.5
±
17.4 167.9
±
17.8 0.855 138.8
±
24.8 140.4
±
25.7 0.656 163.6
±
15.8 166.4
±
21.2 0.260 132.3
±
22.7 128.7
±
23.1 0.231 149.5
±
25.5 149.5
±
27.9 149.3
±
26.9 0.981
DBP (mmHg)
102.9
±
11.4 100.4
±
12.2 0.221 84.8
±
11.8 86.2
±
14.4 0.462 98.2
±
11.5 96.4
±
11.3 0.248 84.8
±
13.9 82.2
±
15.2 0.183 91.9
±
14.4 90.6
±
15.3 91.1
±
14.9 0.239
History of HTN,
n
(%)
Yes
01 (1.9)
05 (5.1) 0.423 50 (57.5)
82 (66.1) 0.248 81 (69.8)
93 (75.6) 0.383 38 (36.9)
55 (40.1) 0.688 170 (47.2) 235 (48.8) 405 (48.1) 0.729
No
53 (98.1)
93 (94.9)
37 (42.5)
42 (33.9)
35 (30.2)
30 (24.4)
65 (63.1)
82 (59.9)
190 (52.8) 247 (51.2) 437 (51.9)
History of DM,
n
(%)
Yes
06 (11.1)
09 (9.1) 0.778 10 (11.9)
12 (9.7) 0.820 11 (9.6)
14 (11.5) 0.677 06 (5.9)
02 (1.5) 0.077 33(9.3)
37(7.8)
70 (8.4)
0.452
No
48 (88.9)
90 (90.9)
74 (88.1) 104 (90.3)
104 (90.4) 108 (88.5)
97 (94.1) 135 (98.5)
323(90.7) 437(92.2) 760 (91.6)
FBS (mmol/l)
6.2
±
2.8 6.6
±
7.6 0.685 6.2
±
2.9 5.8
±
4.1 0.979 5.4
±
1.8 5.1
±
1.6 0.084 5.9
±
2.0 5.5
±
1.6 0.122 5.8
±
2.3 5.7
±
4.2 5.8
±
3.5 0.798
Lipid profile
TG (mmol/l)
2.4
±
10.0 0.9
±
0.5 0.144 6.8
±
5.8 5.8
±
4.1 0.173 1.1
±
0.6 1.0
±
0.4 0.266 2.1
±
1.4 1.4
±
0.8 0.000 2.9
±
5.3 2.2
±
2.8 2.5
±
4.1 0.019
HDL-C
(mmol/l)
1.2
±
0.5 1.3
±
0.7 0.560 2.6
±
1.1 2.9
±
1.2 0.075 1.2
±
0.3 1.4
±
0.5 0.000 1.3
±
0.6 1.5
±
0.3 0.052 1.6
±
0.9 1.8
±
0.9 1.7
±
0.9 0.004
LDL-C
(mmol/l)
2.8
±
0.8 2.5
±
0.8 0.027 6.1
±
3.3 6.5
±
3.4 0.412 2.8
±
1.2 2.9
±
1.2 0.349 2.5
±
0.8 2.7
±
0.9 0.085 3.4
±
2.3 3.6
±
2.4 3.5
±
2.4 0.436
TC (mmol/l)
4.4
±
0.9 4.2
±
0.9 0.317 8.8
±
4.5 9.2
±
4.8 0.549 4.5
±
0.9 4.7
±
1.1 0.154 4.8
±
0.9 4.9
±
1.1 0.360 5.5
±
2.8 5.7
±
3.0 5.6
±
3.0 0.471
Creatinine
(
µ
mol/l)
108.6
±
35.4 99.2
±
40.4 0.153 56.2
±
21.2 54.5
±
28.4 0.658 107.2
±
43.1 84.9
±
22.1 0.000 88.8
±
17.2 66.4
±
11.4 0.000 90.8
±
37.3 75.7
±
31.1 82.1
±
34.6 0.000
Uric acid (
µ
mol/l) 384.6
±
84.2 298.6
±
119.9
0.000 300.7
±
275.4
264.5
±
242.1
0.350 405.3
±
109.5
354.7
±
100.1
0.000 340.6
±
90.3 249.9
±
67.9 0.000 295.0
±
178.5
233.2
±
154.1
259.3
±
168.0
0.000
Alcohol intake,
n
(%)
Low–moderate 22 (46.8)
49 (75.3) 0.003
–
–
– 52 (70.3)
45 (91.8) 0.006 38 (76.0) 20 (100.0) 0.014 114 (65.9) 115 (85.1) 229 (74.4) 0.000
Excessive
25 (53.2)
16 (24.7)
22 (29.7)
04 (8.2)
12 (34.0)
00 (0.0)
59 (34.1)
20 (14.9)
79 (25.6)
Tobacco use,
n
(%)
Current
05 (9.3)
05 (5.1) 0.004 04 (4.6)
00 (0.0) 0.000 10 (8.7)
01 (0.8) 0.000 26 (25.2)
22 (16.1) 0.007 45 (12.5)
28 (5.7)
73 (8.7)
0.000
Former
08 (14.8)
02 (2.0)
17 (19.7)
00 (0.0)
14 (12.2)
01 (0.8)
19 (18.4)
12 (8.7)
58 (16.1)
15 (3.1)
73 (8.7)
Never
41 (75.9)
92 (92.9)
65 (75.7) 122 (100.0)
91 (79.1) 121 (98.4)
58 (56.3) 103 (75.2)
255 (71.4) 438 (91.2) 693 (82.6)
Employment,
n
(%)
Unemployed
0 (0.0)
14 (14.3)
01 (1.1)
06 (4.5)
12 (10.4)
16 (13.0)
02 (1.9)
06 (4.4)
15(4.1)
42(8.6)
57 (6.8)
Full time
24 (44.4)
22 (22.4)
22 (24.4)
44 (35.3)
60 (51.7)
18 (14.6)
52 (50.5)
71 (51.8)
158(43.5) 155(31.8) 313 (37.2) 0.000
Part time
05 (9.3)
02 (2.0) 0.000 03 (3.3)
01 (0.8) 0.010 01 (0.8)
00 (0.0) 0.000 07 (6.8)
06 (4.4) 0.001 16(4.4)
09(1.9)
25 (2.9)
Self-employed 13 (24.1)
09 (9.3)
46 (53.4)
50 (40.1)
24 (20.7)
18 (14.6)
29 (28.2)
24 (17.5)
112 (31.4) 101(21.4) 213 (25.3)
Housewife
00 (0.0)
44 (44.9)
00 (0.0)
09 (7.2)
00 (0.0)
63 (51.2)
00 (0.0)
19 (13.8)
01 (0.3)
135(27.8) 136 (16.2)
Retired
12 (22.2)
07 (7.1)
15 (17.8)
15 (12.1)
19 (16.4)
08 (6.5)
13 (12.6)
11 (8.0)
58 (16.3)
40(8.5)
98 (11.6)
Education,
n
(%)
None
01 (1.9)
15 (15.3)
01 (2.2)
11 (8.9)
02 (1.7)
18 (14.6)
00 (0.0)
01 (0.7)
04 (1.2)
45 (9.4)
49 (5.8)
Primary school
12 (22.2)
38 (38.7) 0.000 54 (61.1)
70 (56.9) 0.113 05 (4.3)
31 (25.2) 0.000 11 (10.7)
12 (8.8) 0.024 82 (22.8) 151 (31.4) 233 (27.7) 0.000
High school
18 (33.3)
25 (25.5)
09 (10.0)
14 (11.4)
40 (34.5)
42 (34.1)
19 (18.4)
51 (37.2)
86 (23.8) 132 (27.4) 218 (25.9)
Diploma
08 (14.8)
15 (15.3)
00 (0.0)
00 (0.0)
26 (22.4)
18 (14.6)
25 (24.3)
27 (19.7)
59 (16.4)
60 (12.5) 119 (14.1)
Degree
15 (27.8)
05 (5.2)
23 (26.7)
28 (22.8)
43 (37.1)
14 (11.4)
48 (46.6)
46 (33.6)
129 (35.8) 93 (19.3) 222 (26.5)
Residence,
n
(%)
Urban
47 (87.0)
81 (82.6) 0.643 45 (51.7)
70 (56.9) 0.484 113 (97.4) 120 (97.5) 0.942 71 (68.9) 100 (72.9) 0.565 276 (76.6) 371 (77.1) 647 (76.9) 0.988
Semi-urban
07 (13.0)
17 (17.4)
42 (48.3)
53 (43.1)
03 (2.6)
03 (2.5)
32 (31.1)
37 (27.1)
84 (23.4) 110 (22.9) 194 (23.1)
BMI
=
body mass index; WC
=
waist circumference; HC
=
hip circumference; SBP
=
systolic blood pressure; DBP
=
diastolic blood pressure; DM
=
diabetes mellitus; HTN
=
hypertension; FBS
=
fasting
blood sugar; TG
=
triglycerides; HDL-C
=
high-density lipoprotein cholesterol; LDL-C
=
low-density lipoprotein cholesterol; TC
=
total cholesterol; DRC
=
Democratic Republic of Congo;
p
-values are for comparison between gender among participating countries.