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CARDIOVASCULAR JOURNAL OF AFRICA • Volume 31, No 6, November/December 2020

AFRICA

285

The authors of the PASCAR commentary (page 325) on the

recently published International Society of Hypertension (ISH)

global guidelines are to be congratulated on an important,

pragmatic and clinically useful commentary that should be read

by all who measure and treat the blood pressure of persons in

sub-Saharan Africa (SSA). They draw on their extensive clinical

experience and personal knowledge of the healthcare situation

in SSA to put the ISH guidelines in context for the continent.

They start with a brief but informative discussion for the

rationale and usefulness of guidelines and then go on to point

out where the guidelines need to be modified or altered by the

availability of testing devices and laboratory services. Importantly,

they point out that some of the medicines recommended for the

treatment of hypertension are not available in much of SSA

and those that are, such as intravenous nitrates, may require

scarce intensive-care facilities. In each instance the PASCAR

commentary offers clinically helpful comments and alternatives.

This commentary should be copied and made available to all

healthcare practitioners in SSA.

The value of a commentary such as that of PASCAR becomes

immediately apparent on reading the contribution of Hu and

colleagues (page 298) who measured uric acid (UA) levels in a

large cohort of hypertensive patients in China. They concluded

that high UA level could significantly increase stroke risk in

female hypertensive patients and that these patients may benefit

from managing UA at normal levels. The PASCAR commentary

offers explicit advice to the contrary. ‘The recommendation

for treating asymptomatic hyperuricaemia is considered very

controversial.’

The importance of establishing norms and values for

determination and description of disease states and metabolic

disturbance in populations in SSA is further illustrated by the

contribution of Tladi and colleagues (page 314). They studied

Batswana adults and determined demographic and anthropometric

measurements and other risk factors for the metabolic syndrome

in 384 men and 416 women in Gaborone and surrounding villages.

They concluded that there is a difference between the cut-off values

for Europeans and those determined for the Batswana in terms of

the definition of abdominal obesity in adults, and inconsistencies in

cut-off values used have the potential for undesirable consequences

for cardiovascular risk stratification.

From Abidjan, Yao and collaborators (page 319) report that

the prevalence of admission hyperglycaemia was 40.6% in a large

number of black Africans presenting with an acute coronary

syndrome (ACS). This study, carried out in a SSA population,

shows that in the acute phase of ACS, admission blood glucose

has a powerful prognostic value on mortality rate, in accordance

with studies conducted in the West.

The CVJA is privileged to be able to continue publishing these

and other articles, documenting and commenting on patterns of

cardiovascular disease in Africa.

Pat Commerford

Editor-in-Chief

From the Editor’s Desk

The management and staff of Clinics Cardive Publishing

(publishers of the

Cardiovascular Journal of Africa

and the

South African

Journal of Diabetes & Vascular Disease

) thank all our authors, reviewers and

clients for your continued support and collaboration.

We wish you a happy holiday season and a peaceful and prosperous new year.

Please note that our office will close on Tuesday 15 December

and open on Thursday 14 January 2021.

We look forward to being of service to you in the new year.