CARDIOVASCULAR JOURNAL OF AFRICA • Volume 25, No 2, March/April 2014
AFRICA
49
of LVEF obtained by one operator is used, changes of more than
3% are of concern.
A limitation of this study was that most of the LVEFs fell
within the normal range.
Conclusion
The results of this study are consistent with reports that
software programs for processing GBP studies cannot be used
interchangeably and each department must establish its own
values for clinical decision-making. The software used to
calculate the result should be identified in the report. Studies
should be processed at least three times. The mean of the two
closest estimates would probably be the best representation of the
patient’s LVEF. Acquisition of GBP studies on different cameras
did not influence results.
References
1.
Hesse B, Lindhardt TB, Acampa W, Anagnostopoulos C, Ballinger
J, Bax JJ,
et al
. EANM/ESC guidelines for radionuclide imaging of
cardiac function
. Eur J Nucl Med Mol Imaging
2008;
35
(4): 851–885.
2.
Hendel RC, Berman DS, Di Carli MF, Heidenreich PA, Henkin RE,
Pellikka PA,
et al
. ACCF/ASNC/ACR/AHA/ASE/SCCT/SCMR/SNM
2009 appropriate use criteria for cardiac radionuclide imaging: A report
of the American College of Cardiology Foundation Appropriate Use
Criteria Task Force, the American Society of Nuclear Cardiology, the
American College of Radiology, the American Heart Association, the
American Society of Echocardiography, the Society of Cardiovascular
Computed Tomography, the Society for Cardiovascular Magnetic
Resonance, and the Society of Nuclear Medicine.
J Am Coll Cardiol
2009;
53
(23): 2201–2229.
3.
Hiscock SC, Evans MJ, Morton RJ, Hall DO. Investigation of normal
ranges for left ventricular ejection fraction in cardiac gated blood pool
imaging studies using different processing workstations
. Nucl Med
Commun
2008;
29
(2): 103–109.
4.
Skrypniuk JV, Bailey D, Cosgriff PS, Fleming JS, Houston AS, Jarritt
PH,
et al
. UK audit of left ventricular ejection fraction estimation from
equilibrium ECG gated blood pool images
. Nucl Med Commun
2005;
26
(3): 205–215.
5.
Fair JR, Heintz PH, TelepakRJ. Evaluation of new data processing algo-
rithms for planar gated ventriculography (MUGA).
J Appl Clin Med
Phys
2009;
10
(3): 173–179.
6.
PuchalAñé R, GuiraoMarín S, DomènechVilardell A, Rodríguez
Gassén A, BajénLázaro MT, RicartBrulles Y,
et al.
Calculation of
the left ventricular ejection fraction. Comparison between 4 different
instruments
. Rev Esp Med Nucl
2008;
27
(6): 418–423.
7.
Bailey EA, Bailey DL. Results from an Australian and New Zealand
audit of left ventricular ejection fraction from gated heart pool scan
analysis.
Nucl Med Commun
2012;
33
(1): 102–111.
8.
Scheiner J, Sinusas A, Wittry MD, Royal HD, Machac J, Balon HR,
et
al
. Society of Nuclear Medicine procedure guideline for gated equilib-
rium radionuclide ventriculography 2002.
docs/pg ch01 0403.pdf. (accessed 10 September 2009).
9.
Lauritsen JM, Bruus M. EpiData (version 3). A comprehensive tool for
validated entry and documentation of data. The EpiData Association,
Odense Denmark, 2003–2004.
10. Stata 11.1: StataCorp LP, 4905 Lakeway Station, TX 77845, USA.
11. Van Royen N, Jaffe CC, Krumholz HM, Johnson KM, Lynch PJ, Natale
D,
et al.
Comparison and reproducibility of visual echocardiographic
and quantitative radionuclide left ventricular ejection fractions
. Am J
Cardiol
1996;
77
(10): 843–850.
12. Pfisterer ME, Battler A, Zaret BL. Range of normal values for left and
right ventricular ejection fraction at rest and during exercise assessed
by radionuclide angiocardiography.
Eur Heart J
1985;
6
(8): 647–655.
13. HainsAD, Al-Khawaja I, Hinge DA, Lahiri A, Raftery EB. Radionuclide
left ventricular ejection fraction: a comparison of three methods
. Br
Heart J
1987;
53
(3): 242–246.
14. Castell-Conesa J, Aguadé-Bruix S, García-Burillo A, González JM,
Canela T, Oller G,
et al
. Reproducibility of measurements of left
ventricular function with gated myocardial perfusion SPECT and
comparison with blood pool radionuclide ventriculography.
Rev Esp
Cardiol
2004;
57
(10): 931–938.
15. Jannazzo A, Hoffman J, Lutz M. Monitoring of anthracycline-induced
cardiotoxicity.
Ann Pharmacother
2008;
42
(1): 99–104.
16. Valkoma R, Pauwels EKJ, Arnt JW. Nuclear medicine procedures. In:
Peckham M, Pinedo HM, Veronesi U.
Oxford Textbook of Oncology
.
Oxford: Oxford Medical, 1995; 1: 434. ISBN 0 19 262663 9.