Background Image
Table of Contents Table of Contents
Previous Page  11 / 84 Next Page
Information
Show Menu
Previous Page 11 / 84 Next Page
Page Background

CARDIOVASCULAR JOURNAL OF AFRICA • Volume 29, No 2, March/April 2018

AFRICA

73

Prevalence, awareness, treatment and control of

hypertension, diabetes and hypercholesterolaemia

among adults in Dande municipality, Angola

João M Pedro, Miguel Brito, Henrique Barros

Abstract

Objectives:

To estimate the prevalence, awareness, treatment

and control of hypertension, diabetes and hypercholesterol-

aemia in an Angolan population aged 15 to 64 years and to

determine relationships with sociodemographic, behavioural

and anthropometric characteristics.

Methods:

A total of 2 354 individuals were assessed for behav-

ioural, sociodemographic and physical characteristics in a

cross-sectional, community-based survey. Post-stratification

survey weights were applied to obtain prevalence levels.

Adjusted odds ratios for each variable related to the condi-

tions were calculated using logistic regression models.

Results:

Overall, the prevalence of hypertension was 18.0%,

diabetes 9.2% and hypercholesterolaemia 4.0%. Among

hypertensive individuals, the awareness rate was 48.5%;

15.8% were on treatment and 9.1% had their blood pressure

controlled. Only 10.8% were aware they had diabetes, 4.5%

were on treatment and 2.7% were controlled. The awareness

level for hypercholesterolaemia was 4.2%, with 1.4% individu-

als on treatment and 1.4% controlled.

Conclusions:

The prevalence levels of hypertension and diabe-

tes, which were higher than previous findings for the region,

together with the observed low rates of awareness, treatment

and control of all conditions studied, constitute an additional

challenge to the regional health structures, which must rapidly

adapt to the epidemiological shift occurring in this population.

Keywords:

epidemiology, hypertension, diabetes, hypercholester-

olaemia, sub-Saharan Africa

Submitted 25/11/16, accepted 7/11/17

Published online 14/12/17

Cardiovasc J Afr

2017;

29

: 73–81

www.cvja.co.za

DOI: 10.5830/CVJA-2017-047

Cardiovasculardisease(CVD),amajorcauseof non-communicable

diseases (NCDs), was responsible for 17.5 million deaths

worldwide in 2012, most occurring in low- and middle-income

countries (LMIC). In Africa, the frequency of NCDs is rising

rapidly, reflecting the combined effect of population growth and

ageing, as well as nutritional and epidemiological transitions.

1

A large proportion of CVD is the result of exposure to

modifiable risk factors (tobacco and alcohol consumption,

unhealthy diet and physical inactivity), which influence metabolic

pathways and ultimately result in obesity, hypertension, diabetes or

hypercholesterolaemia.

1,2

Together, these known adverse conditions

explain approximately half of CVD cases, as demonstrated in the

MONICA project and the INTERHEART study.

3,4

Among the African population participating in the

INTERHEART study, five risk factors (smoking, diabetes,

hypertension, abdominal obesity and an elevated apolipoprotein

B to apolipoprotein A-1 ratio) accounted for 89.2% of the

population-attributable risk for the first myocardial infarction.

5

The same study suggested that uncontrolled major risk factors

have a larger impact on the burden of CVD in Africa than

elsewhere in the world.

5

If the current trends persist, the risk of dying from NCDs

will increase in the African region. However, this rising risk

could be reversed by reaching the proposed targets for six

behavioural and physiological risk factors (tobacco and alcohol

use, salt intake, obesity and increased blood pressure and glucose

levels) out of the nine global targets proposed by the World

Health Organisation (WHO) in the Global Action Plan for the

Prevention and Control of NCD 2013–2020.

6,7

To follow the achievement of those goals, there is a need for

sound and updated epidemiological data from all regions of the

world. The majority of published studies for the African region

are conducted at hospital services, which does not allow one

to detect risk factors, awareness rates and prevalence of such

conditions in the general population.

8-10

To provide core data on

established risk factors for the major NCDs within the context

of low-resource settings, WHO designed the STEPwise approach

to Surveillance (STEPS).

11

STEPS uses a modular structure with

standardised questions and protocols, allowing adjustment of its

application and appropriate comparisons across surveys.

11

In Angola, infectious disease and maternal and child health-

related problems remain the major causes of morbidity and

mortality.

12

However, an increased burden of NCDs has been

observed, particularly CVD, which was responsible for 9% of

adult deaths in 2013.

13

Beyond general vital statistics, specific

epidemiological information on CVD risk factors in Angola is

based on only four local studies published after 2000: a survey

of 667 adult students of Health Sciences in Lubango (prevalence

of hypertension of 23.5%),

14

a study conducted among 615

active employees of the University Agostinho Neto, Luanda

CISA, Centro de Investigação em Saúde de Angola, Caxito,

Angola

João M Pedro, BPharm, MEd,

joao.almeidapedro@cisacaxito.org

Miguel Brito, PhD

EPIUnit, Instituto de Saúde Pública, Universidade do Porto,

Porto, Portugal

João M Pedro, BPharm, MEd

Henrique Barros, MD, PhD

Escola Superior de Tecnologia da Saúde de Lisboa,

Instituto Politécnico de Lisboa, Lisboa, Portugal

Miguel Brito, PhD

Faculdade de Medicina, Universidade do Porto, Porto, Portugal

Henrique Barros, MD, PhD